Publications by authors named "Michael P Carty"

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Canonical and Non-Canonical Roles of Human DNA Polymerase η.
Salma Bedaiwi, Anam Usmani, Michael P Carty

Genes (Basel)· September 2024

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Heterocyclic Iminoquinones and Quinones from the National Cancer Institute (NCI, USA) COMPARE Analysis.
Naemah Haji, Masoma Faizi, Panayiotis A Koutentis, Michael P Carty, Fawaz Aldabbagh

Molecules· July 2023

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DNA Damage Tolerance Pathways in Human Cells: A Potential Therapeutic Target.
Ashlynn Ai Li Ler, Michael P Carty

Front Oncol· February 2022

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N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines.
Jian Zhou, Arvind Negi, Styliana I Mirallai, Rolf Warta, Christel Herold-Mende, Michael P Carty

Bioorg Chem· March 2019

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Selective Methylmagnesium Chloride Mediated Acetylations of Isosorbide: A Route to Powerful Nitric Oxide Donor Furoxans.
Patrick Kielty, Dennis A Smith, Peter Cannon, Michael P Carty, Michael Kennedy

Org Lett· May 2018

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Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors.
Lee-Ann J Keane, Styliana I Mirallai, Martin Sweeney, Michael P Carty, Georgia A Zissimou

Molecules· March 2018

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Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition.
Martin Sweeney, Robert Coyle, Paul Kavanagh, Andrey A Berezin, Daniele Lo Re, Michael P Carty

Bioorg Med Chem· August 2016

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DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells.
Anna M Sokol, Séverine Cruet-Hennequart, Philippe Pasero, Michael P Carty

Sci Rep· November 2013

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Doxorubicin induces the DNA damage response in cultured human mesenchymal stem cells.
Séverine Cruet-Hennequart, Áine M Prendergast, Georgina Shaw, Frank P Barry, Michael P Carty

Int J Hematol· November 2012

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COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.
Vincent Fagan, Sarah Bonham, Michael P Carty, Patricia Saenz-Méndez, Leif A Eriksson

Bioorg Med Chem· May 2012

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Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation.
Áine M Prendergast, Séverine Cruet-Hennequart, Georgina Shaw, Frank P Barry, Michael P Carty

Cell Cycle· November 2011

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First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation towards normal and breast cancer cell lines.
Sarah Bonham, Liz O'Donovan, Michael P Carty, Fawaz Aldabbagh

Org Biomol Chem· October 2011

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Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.
Sandra Cuffe, Catherine M Dowling, James Claffey, Clara Pampillón, Megan Hogan, Michael P Carty

Prostate· February 2011

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Analysis of protein phosphorylation in cisplatin-treated human cells following annexin V-based separation and multi-antibody screening.
Elaine O'Meara, Séverine Cruet-Hennequart, Michael P Carty

Cancer Genomics Proteomics· January 2011

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Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents.
Eoin Moriarty, Miriam Carr, Sarah Bonham, Michael P Carty, Fawaz Aldabbagh

Eur J Med Chem· September 2010

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One-pot double intramolecular homolytic aromatic substitution routes to dialicyclic ring fused imidazobenzimidazolequinones and preliminary analysis of anticancer activity.
Vincent Fagan, Sarah Bonham, Michael P Carty, Fawaz Aldabbagh

Org Biomol Chem· July 2010

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DNA polymerase eta, a key protein in translesion synthesis in human cells.
Séverine Cruet-Hennequart, Kathleen Gallagher, Anna M Sokòl, Sangamitra Villalan, Aine M Prendergast, Michael P Carty

Subcell Biochem· June 2010

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Human mesenchymal stem cells (hMSCs) as targets of DNA damaging agents in cancer therapy.
Séverine Cruet-Hennequart, Aine M Prendergast, Frank P Barry, Michael P Carty

Curr Cancer Drug Targets· June 2010

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The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells.
Karen Fahey, Liz O'Donovan, Miriam Carr, Michael P Carty, Fawaz Aldabbagh

Eur J Med Chem· May 2010

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New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.
Renata Grzywa, Anna M Sokol, Marcin Sieńczyk, Magdalena Radziszewicz, Beata Kościołek, Michael P Carty

Bioorg Med Chem· April 2010

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Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis.
Holger Stephan, Claire Concannon, Elisabeth Kremmer, Michael P Carty, Heinz-Peter Nasheuer

Nucleic Acids Res· October 2009

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Characterization of the effects of cisplatin and carboplatin on cell cycle progression and DNA damage response activation in DNA polymerase eta-deficient human cells.
Séverine Cruet-Hennequart, Sangamitra Villalan, Agnieszka Kaczmarczyk, Elaine O'Meara, Anna M Sokol, Michael P Carty

Cell Cycle· September 2009

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First synthesis of N-[(aziridin-2-yl)methyl]benzimidazolequinone and analysis of toxicity towards normal and Fanconi anemia cells.
Liz O'Donovan, Michael P Carty, Fawaz Aldabbagh

Chem Commun (Camb)· November 2008

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Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin.
Séverine Cruet-Hennequart, Macdara T Glynn, Laura S Murillo, Seamus Coyne, Michael P Carty

DNA Repair (Amst)· April 2008

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The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.
Annabelle M Flanagan, Gerard Rafferty, Anne O'Neill, Leonie Rynne, Jack Kelly, Michael P Carty

Int J Mol Med· April 2007

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