Publications by authors named "Sarah Bonham"

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A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding.
Chen-Yi Wang, Martin Philpott, Darragh P O'Brien, Anne Ndungu, Jessica Malzahn, Sarah Bonham

Commun Med (Lond)· July 2025

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Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors.
M Letizia Lo Faro, Kaithlyn Rozenberg, Honglei Huang, Sergei Maslau, Sarah Bonham

Kidney Int Rep· May 2024

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Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
Grigory Ryzhakov, Hannah Almuttaqi, Alastair L Corbin, Dorothée L Berthold, Tariq Khoyratty, Sarah Bonham

Nat Commun· November 2021

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Proteomic analysis of machine perfusion solution from brain dead donor kidneys reveals that elevated complement, cytoskeleton and lipid metabolism proteins are associated with 1-year outcome.
L Leonie van Leeuwen, Nora A Spraakman, Aukje Brat, Honglei Huang, Adam M Thorne, Sarah Bonham

Transpl Int· September 2021

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Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis.
Matteo Vecellio, Liye Chen, Carla J Cohen, Adrian Cortes, Yan Li, Sarah Bonham

Arthritis Rheumatol· June 2021

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LARP1 isoform expression in human cancer cell lines.
Hagen Schwenzer, Mai Abdel Mouti, Pia Neubert, Josephine Morris, Joanne Stockton, Sarah Bonham

RNA Biol· February 2021

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Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300.
Lynn M Williams, Fiona E McCann, Marisa A Cabrita, Thomas Layton, Adam Cribbs, Sarah Bonham

Proc Natl Acad Sci U S A· August 2020

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Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570: A Paradigmatic Example of Unspecific Protein Cross-linking with Michael Acceptor Motif-Containing Drugs.
Jennifer A Ward, Adan Pinto-Fernandez, Loïc Cornelissen, Sarah Bonham, Laura Díaz-Sáez

J Med Chem· April 2020

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Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity.
Yurena Vivas-García, Paola Falletta, Jana Liebing, Pakavarin Louphrasitthiphol, Yongmei Feng, Sarah Bonham

Mol Cell· January 2020

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BMP signaling inhibition in secondary cells remodels the seminal proteome and self and rival ejaculate functions.
Ben R Hopkins, Irem Sepil, Sarah Bonham, Thomas Miller, Philip D Charles

Proc Natl Acad Sci U S A· December 2019

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Regulation of the endosomal SNX27-retromer by OTULIN.
Aurelia Stangl, Paul R Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison

Nat Commun· September 2019

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Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells.
David G Saliba, Pablo F Céspedes-Donoso, Štefan Bálint, Ewoud B Compeer, Kseniya Korobchevskaya, Sarah Bonham

Elife· August 2019

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MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Pia-Amata Leimbacher, Samuel E Jones, Ann-Marie K Shorrocks, Mara de Marco Zompit, Matthew Day, Sarah Bonham

Mol Cell· May 2019

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Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Saleta Vazquez-Rodriguez, Miranda Wright, Catherine M Rogers, Adam P Cribbs, Srikannathasan Velupillai, Sarah Bonham

Angew Chem Int Ed Engl· January 2019

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53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Hind Ghezraoui, Catarina Oliveira, Jordan R Becker, Kirstin Bilham, Daniela Moralli, Sarah Bonham

Nature· August 2018

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Cardiac Dysfunction and Metabolic Inflexibility in a Mouse Model of Diabetes Without Dyslipidemia.
Maria Rohm, Dragana Savic, Vicky Ball, M Kate Curtis, Sarah Bonham

Diabetes· June 2018

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A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Aurelia Weber, Paul R Elliott, Adan Pinto-Fernandez, Sarah Bonham, Benedikt M Kessler

Cell Chem Biol· October 2017

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Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.
Qian Wang, Tanja Grkovic, Josep Font, Sarah Bonham, Rebecca H Pouwer

ACS Chem Biol· June 2014

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COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.
Vincent Fagan, Sarah Bonham, Michael P Carty, Patricia Saenz-Méndez, Leif A Eriksson

Bioorg Med Chem· May 2012

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First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation towards normal and breast cancer cell lines.
Sarah Bonham, Liz O'Donovan, Michael P Carty, Fawaz Aldabbagh

Org Biomol Chem· October 2011

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Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents.
Eoin Moriarty, Miriam Carr, Sarah Bonham, Michael P Carty, Fawaz Aldabbagh

Eur J Med Chem· September 2010

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One-pot double intramolecular homolytic aromatic substitution routes to dialicyclic ring fused imidazobenzimidazolequinones and preliminary analysis of anticancer activity.
Vincent Fagan, Sarah Bonham, Michael P Carty, Fawaz Aldabbagh

Org Biomol Chem· July 2010

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El Niño-Southern Oscillation, Pliocene climate and equifinality.
Sarah G Bonham, Alan M Haywood, Daniel J Lunt, Mathew Collins, Ulrich Salzmann

Philos Trans A Math Phys Eng Sci· January 2009

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