Publications by authors named "Michael P Hart"

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Insertion of rare autism variants in synaptic genes induce novel behavioral phenotypes in C. elegans.
Dustin Haskell, William R Haury, Myra M Granato, Brandon L Bastien, Michael P Hart

bioRxiv· December 2025

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Variation in Social Feeding Behaviors and Interactions Among .
Dustin Haskell, Jhelaine Palo, Reina F H Eugene, Christopher R L Large, Michael P Hart

Ecol Evol· November 2025

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Multiple autism genes influence GABA neuron remodeling via distinct developmental trajectories.
Kristi Zoga, Sophia Villiere, Vina Tikiyani, Andrea F Edwards-Cintron, Pranav Thokachichu, Michael P Hart

Genetics· October 2025

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Functional comparison of control and 3' deletion human isoforms in .
Dustin Haskell, Michael P Hart

bioRxiv· September 2025

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Multiple autism genes influence GABA neuron remodeling via distinct developmental trajectories.
Kristi Zoga, Sophia Villiere, Vina Tikiyani, Andrea F Edwards-Cintron, Pranav Thokachichu, Michael P Hart

bioRxiv· June 2025

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nlr-1/CNTNAP regulates dopamine circuit structure and foraging behaviors in C. elegans.
Brandon L Bastien, William R Haury, William R Smisko, Michael P Hart

Commun Biol· October 2024

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Conserved autism-associated genes tune social feeding behavior in C. elegans.
Mara H Cowen, Dustin Haskell, Kristi Zoga, Kirthi C Reddy, Sreekanth H Chalasani, Michael P Hart

Nat Commun· October 2024

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Neurexin drives Caenorhabditis elegans avoidance behavior independently of its post-synaptic binding partner neuroligin.
Caroline S Muirhead, Kirthi C Reddy, Sophia Guerra, Michael Rieger, Michael P Hart

G3 (Bethesda)· August 2024

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Structural neuroplasticity after sleep loss modifies behavior and requires neurexin and neuroligin.
Mara H Cowen, David M Raizen, Michael P Hart

iScience· April 2024

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Conserved autism-associated genes tune social feeding behavior in .
Mara H Cowen, Kirthi C Reddy, Sreekanth H Chalasani, Michael P Hart

bioRxiv· December 2023

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Distinct neurexin isoforms cooperate to initiate and maintain foraging activity.
Brandon L Bastien, Mara H Cowen, Michael P Hart

Transl Psychiatry· November 2023

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CAJAL enables analysis and integration of single-cell morphological data using metric geometry.
Kiya W Govek, Patrick Nicodemus, Yuxuan Lin, Jake Crawford, Artur B Saturnino, Michael P Hart

Nat Commun· June 2023

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Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms.
Fusun Doldur-Balli, Toshihiro Imamura, Olivia J Veatch, Naihua N Gong, Diane C Lim, Michael P Hart

Sleep Med Rev· April 2022

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Stress-Induced Neuron Remodeling Reveals Differential Interplay Between Neurexin and Environmental Factors in .
Michael P Hart

Genetics· December 2019

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Neurexin controls plasticity of a mature, sexually dimorphic neuron.
Michael P Hart, Oliver Hobert

Nature· January 2018

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Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation.
Alyssa N Coyne, Shizuka B Yamada, Bhavani Bagevalu Siddegowda, Patricia S Estes, Benjamin L Zaepfel, Michael P Hart

Hum Mol Genet· December 2015

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Sexual Dimorphism: Mystery Neurons Control Sex-Specific Behavioral Plasticity.
Michael P Hart, Oliver Hobert

Curr Biol· December 2015

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Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions.
Michael P Hart, Johannes Brettschneider, Virginia M Y Lee, John Q Trojanowski, Aaron D Gitler

Acta Neuropathol· August 2012

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Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.
Julien Couthouis, Michael P Hart, Renske Erion, Oliver D King, Zamia Diaz

Hum Mol Genet· July 2012

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ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications.
Michael P Hart, Aaron D Gitler

J Neurosci· July 2012

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A yeast functional screen predicts new candidate ALS disease genes.
Julien Couthouis, Michael P Hart, James Shorter, Mariely DeJesus-Hernandez, Renske Erion

Proc Natl Acad Sci U S A· December 2011

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A yeast model for polyalanine-expansion aggregation and toxicity.
Catherine A Konopka, Melissa N Locke, Pamela S Gallagher, Ngan Pham, Michael P Hart

Mol Biol Cell· June 2011

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Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS.
Zhihui Sun, Zamia Diaz, Xiaodong Fang, Michael P Hart, Alessandra Chesi

PLoS Biol· April 2011

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TDP-43 toxicity in yeast.
Maria Armakola, Michael P Hart, Aaron D Gitler

Methods· March 2011

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Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson

Nature· August 2010

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