Publications by authors named "Michael Properzi"

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Physical activity as a modifiable risk factor in preclinical Alzheimer's disease.
Wai-Ying Wendy Yau, Dylan R Kirn, Jennifer S Rabin, Michael J Properzi, Aaron P Schultz

Nat Med· December 2025

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Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test.
Jessie Fanglu Fu, Talia Robinson, Marina Rodriguez Alonso, Adela Francis Malave, Roos J Jutten, Michael J Properzi

Ann Clin Transl Neurol· November 2025

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Blood-based Transcriptomics Reveal Sex- and Amyloid-Modulated Biology of Plasma pTau217 in Preclinical Alzheimer's Disease.
Mabel Seto, Hannah M Klinger, Michelle Clifton, Vaibhav A Janve, Jane A Brown, Michael Properzi

bioRxiv· November 2025

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Independent effects of white matter lesion volume and APOE ɛ4 on ARIA-H in A4 Study.
Zahra Shirzadi, Aaron P Schultz, Nazila Loghmani, Hyun-Sik Yang, Jeremy Ford, Michael Properzi

Alzheimers Dement· October 2025

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Plasma Phosphorylated Tau181 as a Biomarker for Alzheimer's Disease Co-Pathology in Lewy Body Disease.
Rong Ye, Pia Kivisäkk, Anna Goodheart, Hadia Fatima, Erin Peterec, Michael Properzi

Mov Disord· September 2025

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Estimating the preclinical Alzheimer's disease course with multimodal data.
Diana L Townsend, Michael J Properzi, Tobey J Betthauser, Hannah M Klinger, Rory Boyle

Alzheimers Dement· September 2025

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The Mobile Toolbox for remote, self-administered cognitive assessment in older adults: associations with in-clinic cognitive testing and Alzheimer's disease biomarkers.
Roos J Jutten, Jessa E Burling, Elliott Slade, Jackson C Thompson, Jessie Fanglu Fu, Michael J Properzi

Alzheimers Dement (Amst)· August 2025

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BrainAge moderates associations between Alzheimer's disease biomarkers and cognitive decline: a meta-analysis across A4/LEARN, HABS and ADNI cohorts.
Jorge Garcia Condado, Hannah M Klinger, Colin Birkenbihl, Madison Cuppels, Annie Liu, Michael J Properzi

medRxiv· July 2025

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Relationship between BrainAge Polygenetic Risk Score and plasma biomarkers in the A4/LEARN studies.
Jorge Garcia Condado, Mabel Seto, Madison Cuppels, Colin Birkenbihl, Hannah M Klinger, Michael J Properzi

medRxiv· July 2025

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Sex Differences in Longitudinal Tau-PET in Preclinical Alzheimer Disease: A Meta-Analysis.
Gillian T Coughlan, Hannah M Klinger, Rory Boyle, Tobey J Betthauser, Alexa Pichet Binette, Michael J Properzi

JAMA Neurol· March 2025

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Associations between hormone therapy use and tau accumulation in brain regions vulnerable to Alzheimer's disease.
Gillian T Coughlan, Zoe Rubinstein, Hannah Klinger, Kelly A Lopez, Stephaine Hsieh, Michael Properzi

Sci Adv· March 2025

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Rethinking the residual approach: leveraging statistical learning to operationalize cognitive resilience in Alzheimer's disease.
Colin Birkenbihl, Madison Cuppels, Rory T Boyle, Hannah M Klinger, Oliver Langford, Michael J Properzi

Brain Inform· January 2025

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Latent change-on-change between amyloid accumulation and cognitive decline.
Hannah M Klinger, Brian C Healy, Bernard J Hanseeuw, Rich N Jones, Rory Boyle, Michael J Properzi

Alzheimers Dement· December 2024

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Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease.
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael J Properzi

Nat Med· October 2024

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Rethinking the residual approach: Leveraging machine learning to operationalize cognitive resilience in Alzheimer's disease.
Colin Birkenbihl, Madison Cuppels, Rory T Boyle, Hannah M Klinger, Oliver Langford, Michael J Properzi

medRxiv· September 2024

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Vascular contributions to cognitive decline: Beyond amyloid and tau in the Harvard Aging Brain Study.
Zahra Shirzadi, Rory Boyle, Wai-Ying W Yau, Gillian Coughlan, Jessie Fanglu Fu, Michael J Properzi

J Cereb Blood Flow Metab· August 2024

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Change in Depressive Symptoms and Longitudinal Regional Amyloid Accumulation in Unimpaired Older Adults.
Catherine E Munro, Michelle Farrell, Bernard Hanseeuw, Dorene M Rentz, Rachel Buckley, Michael Properzi

JAMA Netw Open· August 2024

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Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau, and neurodegeneration.
Rory Boyle, Diana L Townsend, Hannah M Klinger, Catherine E Scanlon, Ziwen Yuan, Michael J Properzi

Alzheimers Res Ther· July 2024

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Differential Vulnerability of Hippocampal Subfields to Amyloid and Tau Deposition in the Lewy Body Diseases.
Rong Ye, Anna E Goodheart, Joseph J Locascio, Erin Peterec, Michael Properzi

Neurology· June 2024

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Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the performance-based Harvard Automated Phone Task.
Mark A Dubbelman, Ibai Diez, Christopher Gonzalez, Rebecca E Amariglio, J Alex Becker, Michael J Properzi

Front Aging Neurosci· June 2024

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Increased intraindividual variability in reaction time performance is associated with emerging cognitive decline in cognitively unimpaired adults.
Roos J Jutten, Rebecca E Amariglio, Paul Maruff, Michael J Properzi, Dorene M Rentz

Neuropsychology· February 2024

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Capturing learning curves with the multiday Boston Remote Assessment of Neurocognitive Health (BRANCH): Feasibility, reliability, and validity.
Emma L Weizenbaum, Daniel Soberanes, Stephanie Hsieh, Cassidy P Molinare, Rachel F Buckley, Michael J Properzi

Neuropsychology· February 2024

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Longitudinal associations of apathy and regional tau in mild cognitive impairment and dementia: Findings from the Alzheimer's Disease Neuroimaging Initiative.
Pranitha Y Premnath, Joseph J Locascio, Kayden J Mimmack, Christopher Gonzalez, Michael J Properzi

Alzheimers Dement (N Y)· February 2024

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Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults.
Bernard J Hanseeuw, Heidi I L Jacobs, Aaron P Schultz, Rachel F Buckley, Michelle E Farrell, Michael Properzi

Neurology· December 2023

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Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
Hyun-Sik Yang, Ling Teng, Daniel Kang, Vilas Menon, Tian Ge, Michael Properzi

Nat Commun· November 2023

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