Publications by authors named "Michael Rehli"

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Lactic acid promotes an MDSC-like phenotype via HIF1α stabilization with impact on prognosis in renal cell carcinoma.
Nathalie Babl, Florian Voll, Agnieszka Martowicz, Christina Bruss, Marianna Maddaloni, Michael Rehli

Cancer Lett· December 2025

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Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury.
Julius C Fischer, Sascha Göttert, Maximilian Giller, Paul Heinrich, Kaiji Fan, Michael Rehli

Signal Transduct Target Ther· November 2025

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The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration.
Sascha Göttert, Erik Thiele Orberg, Kaiji Fan, Paul Heinrich, Diana M Matthe, Michael Rehli

Nat Commun· October 2025

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DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts.
Niklas Beumer, Charles D Imbusch, Tamara Kaufmann, Lisa Schmidleithner, Kathrin Gütter, Michael Rehli

Nat Immunol· August 2025

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Expansions of circulating plasmablasts producing commensal-reactive IgA antibodies are predictors for chronic GVHD.
Katharina M Habenicht, Jana Wanzek, Anna Bootz, Simon Schäfer, Lara Vollmer, Michael Rehli

Blood· June 2025

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ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune tolerance.
Philipp Stüve, Gloria J Godoy, Fernando N Ferreyra, Florencia Hellriegel, Fatima Boukhallouk, Michael Rehli

Mol Metab· April 2025

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Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy.
Jeremy G Baldwin, Christoph Heuser-Loy, Tanmoy Saha, Roland C Schelker, Dragana Slavkovic-Lukic, Michael Rehli

Cell· November 2024

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D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells.
Kathrin Hammon, Kathrin Renner, Michael Althammer, Florian Voll, Nathalie Babl, Michael Rehli

Haematologica· August 2024

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Single-cell chromatin accessibility and transposable element landscapes reveal shared features of tissue-residing immune cells.
Malte Simon, Philipp Stüve, Lisa Schmidleithner, Sebastian Bittner, Niklas Beumer, Michael Rehli

Immunity· August 2024

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STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia.
Alexander Fischer, Benjamín Hernández-Rodríguez, Roger Mulet-Lazaro, Margit Nuetzel, Fabian Hölzl, Michael Rehli

Cell Rep· August 2024

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LIM-domain-only 4 (LMO4) enhances CD8 T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
Roland C Schelker, Jessica Fioravanti, Fabio Mastrogiovanni, Jeremy G Baldwin, Nisha Rana, Michael Rehli

Signal Transduct Target Ther· August 2024

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Epigenetic alterations affecting hematopoietic regulatory networks as drivers of mixed myeloid/lymphoid leukemia.
Roger Mulet-Lazaro, Stanley van Herk, Margit Nuetzel, Aniko Sijs-Szabo, Noelia Díaz, Michael Rehli

Nat Commun· July 2024

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Oligoclonal CD4CXCR5 T cells with a cytotoxic phenotype appear in tonsils and blood.
Chunguang Liang, Silvia Spoerl, Yin Xiao, Katharina M Habenicht, Sigrun S Haeusl, Michael Rehli

Commun Biol· July 2024

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Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
Roland Windisch, Sarah Soliman, Adrian Hoffmann, Linping Chen-Wichmann, Anna Danese, Michael Rehli

Proc Natl Acad Sci U S A· June 2024

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Donor regulatory T cells rapidly adapt to recipient tissues to control murine acute graft-versus-host disease.
David J Dittmar, Franziska Pielmeier, Nicholas Strieder, Alexander Fischer, Michael Herbst, Michael Rehli

Nat Commun· April 2024

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The effector program of human CD8 T cells supports tissue remodeling.
Michael Delacher, Lisa Schmidleithner, Malte Simon, Philipp Stüve, Lieke Sanderink, Michael Rehli

J Exp Med· February 2024

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Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas.
Enrique Blanco-Carmona, Ashwin Narayanan, Inmaculada Hernandez, Juan C Nieto, Marc Elosua-Bayes, Michael Rehli

Cell Rep Med· November 2023

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Changes in adenoviral chromatin organization precede early gene activation upon infection.
Uwe Schwartz, Tetsuro Komatsu, Claudia Huber, Floriane Lagadec, Conradin Baumgartl, Michael Rehli

EMBO J· October 2023

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A multilocus genetic risk score for obesity: Association with BMI and metabolic alterations in a cohort with severe obesity.
Sabine Julia Maria Sag, Stephanie Mueller, Stefan Wallner, Christina Strack, Ute Hubauer, Michael Rehli

Medicine (Baltimore)· August 2023

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Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment.
Robert Schoeppe, Nathalie Babl, Sonja-Maria Decking, Gabriele Schönhammer, Andreas Siegmund, Michael Rehli

Front Oncol· January 2023

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Biosensors for inflammation as a strategy to engineer regulatory T cells for cell therapy.
Sebastian Bittner, Brigitte Ruhland, Veronika Hofmann, Lisa Schmidleithner, Kathrin Schambeck, Michael Rehli

Proc Natl Acad Sci U S A· October 2022

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Postmitotic differentiation of human monocytes requires cohesin-structured chromatin.
Julia Minderjahn, Alexander Fischer, Konstantin Maier, Karina Mendes, Margit Nuetzel, Michael Rehli

Nat Commun· July 2022

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Physiological levels of 25-hydroxyvitamin D induce a suppressive CD4 T cell phenotype not reflected in the epigenetic landscape.
Carina Matos, Kathrin Renner, Alice Peuker, Gabriele Schoenhammer, Laura Schreiber, Michael Rehli

Scand J Immunol· May 2022

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Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Antonio Sorrentino, Ayse Nur Menevse, Tillmann Michels, Valentina Volpin, Franziska Christine Durst, Michael Rehli

J Immunother Cancer· May 2022

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Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
Peter J Siska, Sonja-Maria Decking, Nathalie Babl, Carina Matos, Christina Bruss, Michael Rehli

J Clin Invest· November 2021

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