Publications by authors named "Michael Rout"

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Karyopherins remodel the dynamic organization of the nuclear pore complex transport barrier.
Toshiya Kozai, Javier Fernandez-Martinez, Larisa E Kapinos, Paola Gallardo, Trevor van Eeuwen, Michael P Rout

Nat Cell Biol· December 2025

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Breaking Barriers: Respiratory Viral Strategies Targeting the Host's Nuclear Pore Complex and Nuclear Transport Pathways.
Yael Udi, John D Aitchison, Michael P Rout, Samson Obado

Mol Biol Cell· November 2025

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Rapid DNA Cleavage by the LINE-1 Endonuclease Proximal to DNA Ends and at Mismatches.
Bryant D Miller, Benedict A Smail, Trevor Van Eeuwen, Hanna Kodama, Kazuma Kondo, Michael P Rout

J Biol Chem· November 2025

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Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.
Barak Raveh, Roi Eliasian, Shaked Rashkovits, Daniel Russel, Ryo Hayama, Michael P Rout

Proc Natl Acad Sci U S A· October 2025

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The Strange Case of the Noncanonical Lamina: Deep Divisions in Nuclear Organisation?
Mark C Field, Michael P Rout

Subcell Biochem· September 2025

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Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies.
Natalia E Ketaren, Peter C Fridy, Vladimir Malashkevich, Tanmoy Sanyal, Marc Brillantes, Michael P Rout

Structure· April 2025

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Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex.
Tiffany Ge, Donna Garvey Brickner, Kara Zehr, D Jake VanBelzen, Wenzhu Zhang, Michael P Rout

Mol Cell· March 2025

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Phosphate-dependent nuclear export via a non-classical NES class recognized by exportin Msn5.
Ho Yee Joyce Fung, Sanraj R Mittal, Ashley B Niesman, Jenny Jiou, Binita Shakya, Michael P Rout

Nat Commun· March 2025

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Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.
Barak Raveh, Roi Eliasian, Shaked Rashkovits, Daniel Russel, Ryo Hayama, Michael P Rout

bioRxiv· February 2025

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A lineage-specific protein network at the trypanosome nuclear envelope.
Erin R Butterfield, Samson O Obado, Simon R Scutts, Wenzhu Zhang, Brian T Chait, Michael P Rout

Nucleus· December 2024

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Nanobodies: From High-Throughput Identification to Therapeutic Development.
Peter C Fridy, Michael P Rout, Natalia E Ketaren

Mol Cell Proteomics· December 2024

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A new generation of nanobody research tools using improved mass spectrometry-based discovery methods.
Peter C Fridy, Ryan J Farrell, Kelly R Molloy, Sarah Keegan, Junjie Wang, Michael P Rout

J Biol Chem· September 2024

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Phosphate-dependent nuclear export via a novel NES class recognized by exportin Msn5.
Ho Yee Joyce Fung, Sanraj R Mittal, Ashley B Niesman, Jenny Jiou, Binita Shakya, Michael P Rout

bioRxiv· August 2024

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Development and Characterization of 50 nanometer diameter Genetically Encoded Multimeric Nanoparticles.
Cindy M Hernandez, David C Duran-Chaparro, Trevor van Eeuwen, Michael P Rout, Liam J Holt

bioRxiv· July 2024

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Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus.
Natalia E Ketaren, Fred D Mast, Peter C Fridy, Jean Paul Olivier, Tanmoy Sanyal, Michael P Rout

Elife· May 2024

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Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex.
Tiffany Ge, Donna Garvey Brickner, Kara Zehr, D Jake VanBelzen, Wenzhu Zhang, Michael P Rout

bioRxiv· May 2024

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The Molecular Architecture of the Nuclear Basket.
Digvijay Singh, Neelesh Soni, Joshua Hutchings, Ignacia Echeverria, Farhaz Shaikh, Michael P Rout

bioRxiv· March 2024

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Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Eric T Baldwin, Trevor van Eeuwen, David Hoyos, Arthur Zalevsky, Egor P Tchesnokov, Michael P Rout

Nature· February 2024

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Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus.
Natalia E Ketaren, Fred D Mast, Peter C Fridy, Jean Paul Olivier, Tanmoy Sanyal, Michael P Rout

bioRxiv· January 2024

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Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin.
Sanjeev K Choudhry, Maxwell L Neal, Song Li, Arti T Navare, Trevor Van Eeuwen, Michael P Rout

J Cell Biol· September 2023

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Implications of a multiscale structure of the yeast nuclear pore complex.
Christopher W Akey, Ignacia Echeverria, Christna Ouch, Ilona Nudelman, Yi Shi, Michael P Rout

Mol Cell· September 2023

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Dynamic molecular mechanism of the nuclear pore complex permeability barrier.
Toshiya Kozai, Javier Fernandez-Martinez, Trevor van Eeuwen, Paola Gallardo, Larisa E Kapinos, Michael P Rout

bioRxiv· April 2023

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Improving the hole picture: towards a consensus on the mechanism of nuclear transport.
David Cowburn, Michael Rout

Biochem Soc Trans· April 2023

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