Publications by authors named "Michael Thomenius"

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Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies.
John W Lampe, Joshua S Alford, P Ann Boriak-Sjodin, Dorothy Brach, Kat Cosmopoulos, Michael J Thomenius

ACS Med Chem Lett· October 2021

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Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
Michael J Thomenius, Jennifer Totman, Darren Harvey, Lorna H Mitchell, Thomas V Riera

PLoS One· December 2018

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EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL.
Dorothy Brach, Danielle Johnston-Blackwell, Allison Drew, Trupti Lingaraj, Vinny Motwani, Michael J Thomenius

Mol Cancer Ther· November 2017

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Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Lorna H Mitchell, P Ann Boriack-Sjodin, Sherri Smith, Michael Thomenius, Nathalie Rioux

ACS Med Chem Lett· February 2016

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Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability.
Sarah R Horn, Michael J Thomenius, Erika Segear Johnson, Christopher D Freel, Judy Q Wu

Mol Biol Cell· April 2011

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Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc.
Chih-Sheng Yang, Michael J Thomenius, Eugene C Gan, Wanli Tang, Christopher D Freel

EMBO J· September 2010

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Mitochondrial localization of Reaper to promote inhibitors of apoptosis protein degradation conferred by GH3 domain-lipid interactions.
Christopher D Freel, D Ashley Richardson, Michael J Thomenius, Eugene C Gan, Sarah R Horn

J Biol Chem· January 2008

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Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis.
Seth S Margolis, Jennifer A Perry, Craig M Forester, Leta K Nutt, Yanxiang Guo, Michael J Thomenius

Cell· November 2006

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Transition state stabilization by six arginines clustered in the active site of creatine kinase.
Michael J Jourden, Paul R Geiss, Michael J Thomenius, Lindsay A Horst, Melissa M Barty

Biochim Biophys Acta· August 2005

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Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance.
Michael J Thomenius, Clark W Distelhorst

J Cell Sci· November 2003

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Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals.
Zhengqi Wang, Michael H Malone, Michael J Thomenius, Fei Zhong, Fang Xu

J Biol Chem· July 2003

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Asparagine 285 plays a key role in transition state stabilization in rabbit muscle creatine kinase.
Charles L Borders, Katherine M MacGregor, Paul L Edmiston, Elikem R K Gbeddy, Michael J Thomenius

Protein Sci· March 2003

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Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins.
Michael J Thomenius, Nancy S Wang, Edmunds Z Reineks, Zhengqi Wang, Clark W Distelhorst

J Biol Chem· February 2003

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