Publications by authors named "Jennifer A Perry"

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CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias.
Travis J Fleming, Mateusz Antoszewski, Sander Lambo, Michael C Gundry, Riccardo Piussi, Jennifer A Perry

Blood· December 2025

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Single Leg Landing Coordination Variability and Second Injury in Young Athletes After Primary Anterior Cruciate Ligament Reconstruction.
Jennifer A Perry, Jamie M Kronenberg, Staci M Thomas, Mark V Paterno, Robert A Siston

Med Sci Sports Exerc· December 2025

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CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias.
Travis J Fleming, Mateusz Antoszewski, Sander Lambo, Michael C Gundry, Riccardo Piussi, Jennifer A Perry

bioRxiv· December 2024

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Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias.
Min Chul Kwon, Jan Willem Thuring, Olivier Querolle, Xuedong Dai, Tinne Verhulst, Jennifer A Perry

Blood· September 2024

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Pharmacological targeting of the cancer epigenome.
Nathaniel W Mabe, Jennifer A Perry, Clare F Malone, Kimberly Stegmaier

Nat Cancer· June 2024

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Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML.
Wallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, Daniela V Wenge, Florian Perner, Jennifer A Perry

Blood· April 2024

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Inherent genome instability underlies trisomy 21-associated myeloid malignancies.
Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid

Leukemia· March 2024

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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
Ghayas C Issa, Ibrahim Aldoss, John DiPersio, Branko Cuglievan, Richard Stone, Jennifer A Perry

Nature· March 2023

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Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts.
Jana M Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Hannah J Uckelmann, Jennifer A Perry

Cancer Discov· July 2022

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Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts.
Florian Perner, Jayant Y Gadrey, Yijun Xiong, Charles Hatton, Benjamin K Eschle, Jennifer A Perry

Blood· October 2020

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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.
Andrei V Krivtsov, Kathryn Evans, Jayant Y Gadrey, Benjamin K Eschle, Charlie Hatton, Jennifer A Perry

Cancer Cell· December 2019

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Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors.
Shuai Liu, Hailemichael O Yosief, Lingling Dai, He Huang, Gagan Dhawan, Jennifer A Perry

J Med Chem· September 2018

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YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis.
Shuai Ye, Matthew A Lawlor, Adrian Rivera-Reyes, Shaun Egolf, Susan Chor, Jennifer A Perry

Cancer Res· May 2018

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The dTAG system for immediate and target-specific protein degradation.
Behnam Nabet, Justin M Roberts, Dennis L Buckley, Joshiawa Paulk, Shiva Dastjerdi, Jennifer A Perry

Nat Chem Biol· May 2018

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Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands.
Lara N Gechijian, Dennis L Buckley, Matthew A Lawlor, Jaime M Reyes, Joshiawa Paulk, Jennifer A Perry

Nat Chem Biol· April 2018

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Correction to 'Walking with wider steps changes foot placement control, increases kinematic variability and does not improve linear stability'.
Jennifer A Perry, Manoj Srinivasan

R Soc Open Sci· January 2018

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PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer.
Jessie Hao-Ru Hsu, Benjamin Hubbell-Engler, Guillaume Adelmant, Jialiang Huang, Cailin E Joyce, Jennifer A Perry

Cancer Res· September 2017

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Walking with wider steps changes foot placement control, increases kinematic variability and does not improve linear stability.
Jennifer A Perry, Manoj Srinivasan

R Soc Open Sci· September 2017

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Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.
Teru Hideshima, Jun Qi, Ronald M Paranal, Weiping Tang, Edward Greenberg, Jennifer A Perry

Proc Natl Acad Sci U S A· November 2016

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Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer.
Haikuo Zhang, Jun Qi, Jaime M Reyes, Lewyn Li, Prakash K Rao, Jennifer A Perry

Cancer Discov· September 2016

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Preclinical antitumor efficacy of selective exportin 1 inhibitors in glioblastoma.
Adam L Green, Shakti H Ramkissoon, Dilara McCauley, Kristen Jones, Jennifer A Perry

Neuro Oncol· May 2015

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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Jennifer A Perry, Adam Kiezun, Peter Tonzi, Eliezer M Van Allen, Scott L Carter

Proc Natl Acad Sci U S A· December 2014

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Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.
Wanli Tang, Judy Qiju Wu, Yanxiang Guo, David V Hansen, Jennifer A Perry

Mol Biol Cell· August 2008

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Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease.
Carl R Walkley, Rameez Qudsi, Vijay G Sankaran, Jennifer A Perry, Monica Gostissa

Genes Dev· June 2008

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Cdc25 and Wee1: analogous opposites?
Jennifer A Perry, Sally Kornbluth

Cell Div· May 2007

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