Publications by authors named "Michael Waterfield"

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A balancing act in the control of self-antigen expression.
Michael R Waterfield, Mark S Anderson

Nat Immunol· September 2024

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Aire in Autoimmunity.
Corey N Miller, Michael R Waterfield, James M Gardner, Mark S Anderson

Annu Rev Immunol· June 2024

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Ikaros is a principal regulator of Aire mTEC homeostasis, thymic mimetic cell diversity, and central tolerance.
Jun Hyung Sin, Juliana Sucharov, Sujit Kashyap, Yi Wang, Irina Proekt, Michael R Waterfield

Sci Immunol· October 2023

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Republication: Targeting PI3KC2β Impairs Proliferation and Survival in Acute Leukemia, Brain Tumours and Neuroendocrine Tumours.
Danielle Boller, Kathrin T Doepfner, Angela DE Laurentiis, Ana S Guerreiro, Marin Marinov, Michael D Waterfield

Anticancer Res· June 2022

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ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8 T Cell Effector and Memory Responses.
Jun Hyung Sin, Sujit Kashyap, Dante Acenas, Jessica T Cortez, James Lee, Michael R Waterfield

J Immunol· March 2022

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Gene Expression Meta-Analysis Reveals Concordance in Gene Activation, Pathway, and Cell-Type Enrichment in Dermatomyositis Target Tissues.
Jessica Neely, Dmitry Rychkov, Manish Paranjpe, Michael Waterfield, Susan Kim

ACR Open Rheumatol· December 2019

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The epigenetic regulator ATF7ip inhibits expression, regulating Th17 responses.
Jun Hyung Sin, Cassandra Zuckerman, Jessica T Cortez, Walter L Eckalbar, David J Erle, Michael R Waterfield

J Exp Med· September 2019

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Analysis of pulmonary features and treatment approaches in the COPA syndrome.
Jessica L Tsui, Oscar A Estrada, Zimu Deng, Kristin M Wang, Christopher S Law, Michael R Waterfield

ERJ Open Res· April 2018

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Identification of a novel cis-regulatory element essential for immune tolerance.
Taylor N LaFlam, Grégory Seumois, Corey N Miller, Wint Lwin, Kayla J Fasano, Michael Waterfield

J Exp Med· November 2015

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COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.
Levi B Watkin, Birthe Jessen, Wojciech Wiszniewski, Timothy J Vece, Max Jan, Michael R Waterfield

Nat Genet· June 2015

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The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.
Michael Waterfield, Imran S Khan, Jessica T Cortez, Una Fan, Todd Metzger

Nat Immunol· March 2014

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Functional proteomic analysis of long-term growth factor stimulation and receptor tyrosine kinase coactivation in Swiss 3T3 fibroblasts.
Kohji Nagano, Akunna Akpan, Gayathri Warnasuriya, Steven Corless, Nick Totty, Michael Waterfield

Mol Cell Proteomics· December 2012

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Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours.
Danielle Boller, Kathrin T Doepfner, Angela De Laurentiis, Ana S Guerreiro, Marin Marinov, Michael D Waterfield

Anticancer Res· August 2012

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Autoimmunity's collateral damage: Immunodeficiency hints at autoreactivity to cytokines.
Michael Waterfield, Mark S Anderson

Nat Med· September 2011

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Clues to immune tolerance: the monogenic autoimmune syndromes.
Michael Waterfield, Mark S Anderson

Ann N Y Acad Sci· December 2010

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Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells.
Hong-Lin Chan, Hsiu-Chuan Chou, MaCarmen Duran, Jana Gruenewald, Michael D Waterfield

J Biol Chem· February 2010

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mTORbeta splicing isoform promotes cell proliferation and tumorigenesis.
Ganna Panasyuk, Ivan Nemazanyy, Aleksander Zhyvoloup, Valeriy Filonenko, Derek Davies, Michael Waterfield

J Biol Chem· November 2009

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Structural analysis of PI3-kinase isoforms: identification of residues enabling selective inhibition by small molecule ATP-competitive inhibitors.
Marketa J Zvelebil, Michael D Waterfield, Stephen J Shuttleworth

Arch Biochem Biophys· September 2008

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A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding.
Harold B J Jefferies, Frank T Cooke, Parmjit Jat, Christine Boucheron, Tomonobu Koizumi, Michael D Waterfield

EMBO Rep· February 2008

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Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors.
Masahiko Hayakawa, Ken-Ichi Kawaguchi, Hiroyuki Kaizawa, Tomonobu Koizumi, Takahide Ohishi, Michael D Waterfield

Bioorg Med Chem· September 2007

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Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis.
Eleonora Jovceva, Martin R Larsen, Michael D Waterfield, Buzz Baum, John F Timms

J Cell Sci· June 2007

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Exploring the specificity of the PI3K family inhibitor LY294002.
Severine I Gharbi, Marketa J Zvelebil, Stephen J Shuttleworth, Tim Hancox, Nahid Saghir, Michael D Waterfield

Biochem J· May 2007

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Synthesis and biological evaluation of pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as novel PI3 kinase p110alpha inhibitors.
Masahiko Hayakawa, Hiroyuki Kaizawa, Hiroyuki Moritomo, Tomonobu Koizumi, Takahide Ohishi, Michael D Waterfield

Bioorg Med Chem Lett· May 2007

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Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Alison Maloney, Paul A Clarke, Soren Naaby-Hansen, Rob Stein, Jens-Oliver Koopman, Michael Waterfield

Cancer Res· April 2007

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Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.
Masahiko Hayakawa, Hiroyuki Kaizawa, Ken-Ichi Kawaguchi, Noriko Ishikawa, Tomonobu Koizumi, Michael D Waterfield

Bioorg Med Chem· January 2007

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