Publications by authors named "Michael Waterman"

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RNA Secondary Structures with Given Motif Specification: Combinatorics and Algorithms.
Ricky X F Chen, Christian M Reidys, Michael S Waterman

Bull Math Biol· February 2023

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Levenshtein Distance, Sequence Comparison and Biological Database Search.
Bonnie Berger, Michael S Waterman, Yun William Yu

IEEE Trans Inf Theory· June 2021

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Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.
David C Lamb, Tatiana Y Hargrove, Bin Zhao, Zdzislaw Wawrzak, Jared V Goldstone, Michael R Waterman

Mol Biol Evol· March 2021

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Multiscale Feedback Loops in SARS-CoV-2 Viral Evolution.
Christopher Barrett, Andrei C Bura, Qijun He, Fenix W Huang, Thomas J X Li, Michael S Waterman

J Comput Biol· March 2021

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A new statistic for efficient detection of repetitive sequences.
Sijie Chen, Yixin Chen, Fengzhu Sun, Michael S Waterman, Xuegong Zhang

Bioinformatics· November 2019

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Benchmarking of alignment-free sequence comparison methods.
Andrzej Zielezinski, Hani Z Girgis, Guillaume Bernard, Chris-Andre Leimeister, Kujin Tang, Michael S Waterman

Genome Biol· July 2019

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CYP51 as drug targets for fungi and protozoan parasites: past, present and future.
Galina I Lepesheva, Laura Friggeri, Michael R Waterman

Parasitology· December 2018

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Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51.
Tatiana Y Hargrove, Zdzislaw Wawrzak, Paxtyn M Fisher, Stella A Child, W David Nes, Michael R Waterman

J Biol Chem· December 2018

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Generalized correlation measure using count statistics for gene expression data with ordered samples.
Y X Rachel Wang, Ke Liu, Elizabeth Theusch, Jerome I Rotter, Marisa W Medina, Michael S Waterman

Bioinformatics· February 2018

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Optimal choice of word length when comparing two Markov sequences using a χ -statistic.
Xin Bai, Kujin Tang, Jie Ren, Michael Waterman, Fengzhu Sun

BMC Genomics· October 2017

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CAFE: aCcelerated Alignment-FrEe sequence analysis.
Yang Young Lu, Kujin Tang, Jie Ren, Jed A Fuhrman, Michael S Waterman

Nucleic Acids Res· July 2017

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Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia.
Chunxue Wang, Pradeep S Pallan, Wei Zhang, Li Lei, Francis K Yoshimoto, Michael R Waterman

J Biol Chem· June 2017

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Recent Structural Insights into Cytochrome P450 Function.
F Peter Guengerich, Michael R Waterman, Martin Egli

Trends Pharmacol Sci· August 2016

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Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design.
Tatiana Y Hargrove, Laura Friggeri, Zdzislaw Wawrzak, Suneethi Sivakumaran, Eugenia M Yazlovitskaya, Michael R Waterman

J Lipid Res· August 2016

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Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.
Jared V Goldstone, Munirathinam Sundaramoorthy, Bin Zhao, Michael R Waterman, John J Stegeman

Mol Phylogenet Evol· January 2016

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VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.
Galina I Lepesheva, Tatiana Y Hargrove, Girish Rachakonda, Zdzislaw Wawrzak, Sébastien Pomel, Michael R Waterman

J Infect Dis· November 2015

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Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia.
Pradeep S Pallan, Li Lei, Chunxue Wang, Michael R Waterman, F Peter Guengerich

Mol Endocrinol· September 2015

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Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE.
Pradeep S Pallan, Chunxue Wang, Li Lei, Francis K Yoshimoto, Richard J Auchus, Michael R Waterman

J Biol Chem· May 2015

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Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 and its absence in cytochrome P450 17A2.
Pradeep S Pallan, Leslie D Nagy, Li Lei, Eric Gonzalez, Valerie M Kramlinger, Michael R Waterman

J Biol Chem· February 2015

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Gene coexpression measures in large heterogeneous samples using count statistics.
Y X Rachel Wang, Michael S Waterman, Haiyan Huang

Proc Natl Acad Sci U S A· November 2014

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Structural basis for rational design of inhibitors targeting Trypanosoma cruzi sterol 14α-demethylase: two regions of the enzyme molecule potentiate its inhibition.
Laura Friggeri, Tatiana Y Hargrove, Girish Rachakonda, Amanda D Williams, Zdzislaw Wawrzak, Michael R Waterman

J Med Chem· August 2014

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DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections.
Chun-Chi Liu, Yu-Ting Tseng, Wenyuan Li, Chia-Yu Wu, Ilya Mayzus, Michael Waterman

Nucleic Acids Res· July 2014

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New developments of alignment-free sequence comparison: measures, statistics and next-generation sequencing.
Kai Song, Jie Ren, Gesine Reinert, Minghua Deng, Michael S Waterman

Brief Bioinform· May 2014

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Complexes of Trypanosoma cruzi sterol 14α-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: structural basis for pathogen selectivity.
Tatiana Y Hargrove, Zdzislaw Wawrzak, Paul W Alexander, Jason H Chaplin, Martine Keenan, Michael R Waterman

J Biol Chem· November 2013

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A geometric interpretation for local alignment-free sequence comparison.
Ehsan Behnam, Michael S Waterman, Andrew D Smith

J Comput Biol· July 2013

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