Publications by authors named "Michael Welsh"

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Topical mutant allele-specific siRNA delivery for treatment of Meesmann epithelial corneal dystrophy and elucidation of disease biomarkers.
Andrew McLain, Suzanne R Saffie-Siebert, Nadia Sukusu Nielsen, Benjamin Patterson, Carsten Scavenius, Michael Welsh

J Control Release· December 2025

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Host-specific microbiomes of blow flies: ecological drivers and implications for pathogen carriage.
Aram Mikaelyan, Joseph Receveur, Kadie Bernstein, Nicholas J Babcock, Jennifer L Pechal, Michael V Welsh

Front Immunol· December 2025

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A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults.
Jordan L Schultz, Phillip E Gander, Craig D Workman, Laura L Boles Ponto, Stephen Cross, Michael J Welsh

J Parkinsons Dis· November 2025

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Molecular Prosthetics and CFTR Modulators Additively Increase Secretory HCO Flux in Cystic Fibrosis Airway Epithelia.
Nohemy Celis, Danforth P Miller, Thomas E Tarara, Jeffry G Weers, Ian M Thornell, Michael J Welsh

ACS Chem Biol· November 2025

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Risk assessment for vaccination programmes in a pandemic. A Swedish model for efficacy and safety during COVID-19.
Gerhard Wikstöm, Michael Welsh

Ups J Med Sci· November 2025

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Does a lack of juveniles indicate a threat? Understanding body size distributions in a group of long-lived vertebrates.
Donald T McKnight, Deborah S Bower, Ellen Ariel, Stephen Beatty, Simon Clulow, Michael A Welsh

J Anim Ecol· October 2025

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Rewriting the Chapter on Cystic Fibrosis: The 2025 Lasker-DeBakey Clinical Medical Research Award.
Michael J Welsh

JAMA· October 2025

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Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Michael Welsh

Mol Oncol· October 2025

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SwsB Acts as a Muramic-δ-lactam Cyclase in Spore Peptidoglycan Synthesis.
Madison E Hopkins, Zachary Yasinov, Mark J Fakler, Grace E Wilde, Katherine G Wetmore, Michael A Welsh

Biochemistry· September 2025

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Molecular prosthetics for CFTR designed for anion selectivity outperform amphotericin B in cultured cystic fibrosis airway epithelia.
Jonnathan P Marin-Toledo, Daniel Greenan, Nohemy Celis, Laura Haske, Agnieszka Lewandowska, Michael J Welsh

bioRxiv· August 2025

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Molecular prosthetics and CFTR modulators additively increase secretory HCO flux in cystic fibrosis airway epithelia.
Nohemy Celis, Danforth P Miller, Thomas E Tarara, Jeffry G Weers, Ian M Thornell, Michael J Welsh

bioRxiv· June 2025

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Do pulmonary ionocytes absorb chloride or secrete chloride?
Ian M Thornell, Lei Lei, Paul B McCray, Michael J Welsh

Am J Physiol Cell Physiol· February 2025

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The oxygen level in air directs airway epithelial cell differentiation by controlling mitochondrial citrate export.
Bo Ram Kim, Adam J Rauckhorst, Michael S Chimenti, Tayyab Rehman, Henry L Keen, Michael J Welsh

Sci Adv· January 2025

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The arc of discovery, from the description of cystic fibrosis to effective treatments.
Michael J Welsh

J Clin Invest· October 2024

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Development and Initial Characterization of Pigs with Mutations and Primary Ciliary Dyskinesia.
Mahmoud A Abou Alaiwa, Brie M Hilkin, Margaret P Price, Nicholas D Gansemer, Michael R Rector, Michael J Welsh

bioRxiv· August 2024

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Epithelial responses to CFTR modulators are improved by inflammatory cytokines and impaired by antiinflammatory drugs.
Tayyab Rehman, Alejandro A Pezzulo, Andrew L Thurman, Rachel L Zemans, Michael J Welsh

JCI Insight· June 2024

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Arteriovenous metabolomics in pigs reveals CFTR regulation of metabolism in multiple organs.
Hosung Bae, Bo Ram Kim, Sunhee Jung, Johnny Le, Dana van der Heide, Michael J Welsh

J Clin Invest· May 2024

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A pilot dose-finding study of Terazosin in humans.
Jordan L Schultz, Phillip E Gander, Craig D Workman, Laura L Ponto, Stephen Cross, Michael J Welsh

medRxiv· May 2024

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Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage.
Akansha Jain, Bo Ram Kim, Wenjie Yu, Thomas O Moninger, Philip H Karp, Michael J Welsh

Proc Natl Acad Sci U S A· March 2024

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A model for stimulation of enzyme activity by a competitive inhibitor based on the interaction of terazosin and phosphoglycerate kinase 1.
Mitchell J Riley, Colleen C Mitchell, Sarah E Ernst, Eric B Taylor, Michael J Welsh

Proc Natl Acad Sci U S A· February 2024

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Injectable long-acting ivacaftor-loaded poly (lactide-co-glycolide) microparticle formulations for the treatment of cystic fibrosis: In vitro characterization and in vivo pharmacokinetics in mice.
David S Nakhla, Aml I Mekkawy, Youssef W Naguib, Aaron D Silva, Dylan Gao, Michael J Welsh

Int J Pharm· January 2024

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CFTR-rich ionocytes mediate chloride absorption across airway epithelia.
Lei Lei, Soumba Traore, Guillermo S Romano Ibarra, Philip H Karp, Tayyab Rehman, Michael J Welsh

J Clin Invest· October 2023

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Novel hybrid silicon-lipid nanoparticles deliver a siRNA to cure autosomal dominant osteopetrosis in mice. Implications for gene therapy in humans.
Antonio Maurizi, Piergiorgio Patrizii, Anna Teti, Flavia Maria Sutera, Paulina Baran-Rachwalska, Michael Welsh

Mol Ther Nucleic Acids· September 2023

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Implications of Pediatric Artificial Intelligence Challenges for Artificial Intelligence Education and Curriculum Development.
Dana Alkhulaifat, Patricia Rafful, Vahid Khalkhali, Michael Welsh, Susan T Sotardi

J Am Coll Radiol· August 2023

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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Yi Jin, Yindi Ding, Mark Richards, Mika Kaakinen, Wolfgang Giese, Michael Welsh, Lena Claesson-Welsh

Nat Cardiovasc Res· December 2022

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