Publications by authors named "Michael Whitfield"

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Sclerotic GVHD and scleroderma share dysregulated gene expression that is ameliorated by EREG therapeutic antibody.
Nathan M Newton, Kriti Agrawal, Anahi V Odell, Timothy Tracy, Craig Hackett, Michael Whitfield

Blood· December 2025

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RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis.
Rezvan Parvizi, Zhiyun Gong, Helen C Jarnagin, Diana M Toledo, Tamar R Abel, Michael L Whitfield

Ann Rheum Dis· December 2025

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Multimodal Analyses of Early, Untreated SSc Skin Identify a Proinflammatory Vascular Niche of Macrophage-Fibroblast Signaling.
Helen C Jarnagin, Rezvan Parvizi, Zhiyun Gong, Rosemary Gedert, Xianying Xing, Michael L Whitfield

JCI Insight· December 2025

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Anti-CD206 CAR T Cell Treatment Restores Fibrosis-Induced Loss of Dermal White Adipose Tissue.
Chanhyuk Park, Asmaa O Mohamed, Helen C Jarnagin, Rajan Bhandari, Jason Gunn, Michael L Whitfield

bioRxiv· October 2025

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Geographic Clustering of Systemic Sclerosis in Areas of Environmental Pollution.
Noelle N Kosarek, Megan E Romano, Erika L Moen, Robert W Simms, Ashleigh Erickson, Michael L Whitfield

Arthritis Care Res (Hoboken)· July 2025

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T Cells Enhance Tissue Complexity and Function to Study Fibrosis in 3D Skin-Like Tissue Models.
Isha Singh, Madeline Morrisson, Sasha Shenk, Helen Jarnagin, Johanna Hauer, Michael L Whitfield

Tissue Eng Part C Methods· July 2025

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Mycophenolate mofetil directly modulates myeloid viability and pro-fibrotic activation of human macrophages.
Emily A Morris, Rezvan Parvizi, Nicole M Orzechowski, Michael L Whitfield, Patricia A Pioli

Rheumatology (Oxford)· May 2025

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Comparative Effectiveness of mRNA-1273 and BNT162b2 COVID-19 Vaccines Among Adults with Underlying Medical Conditions: Systematic Literature Review and Pairwise Meta-Analysis Using GRADE.
Xuan Wang, Ankit Pahwa, Mary T Bausch-Jurken, Anushri Chitkara, Pawana Sharma, Michael Gordon Whitfield

Adv Ther· May 2025

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Publisher Correction: An international perspective on the future of systemic sclerosis research.
David J Abraham, Carol M Black, Christopher P Denton, Jörg H W Distler, Robyn Domsic, Michael L Whitfield

Nat Rev Rheumatol· April 2025

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An international perspective on the future of systemic sclerosis research.
David J Abraham, Carol M Black, Christopher P Denton, Jörg H W Distler, Robyn Domsic, Michael L Whitfield

Nat Rev Rheumatol· March 2025

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Prediction of pyrazinamide resistance in using structure-based machine-learning approaches.
Joshua J Carter, Timothy M Walker, A Sarah Walker, Michael G Whitfield, Glenn P Morlock

JAC Antimicrob Resist· April 2024

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Single-cell epigenomic dysregulation of Systemic Sclerosis fibroblasts via CREB1/EGR1 axis in self-assembled human skin equivalents.
Tamar R Abel, Noelle N Kosarek, Rezvan Parvizi, Helen Jarnagin, Gretel M Torres, Michael L Whitfield

bioRxiv· March 2024

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Bedaquiline for treatment of non-tuberculous mycobacteria (NTM): a systematic review and meta-analysis.
Shatha Omar, Michael G Whitfield, Margaret B Nolan, Justice T Ngom, Nabila Ismail

J Antimicrob Chemother· February 2024

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Gene Expression Signatures in Inflammatory and Sclerotic Morphea Skin and Sera Distinguish Morphea from Systemic Sclerosis.
Henry W Chen, Jane L Zhu, Viktor Martyanov, Lam C Tsoi, Michael E Johnson, Michael Whitfield

J Invest Dermatol· October 2023

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CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma.
Gretel M Torres, Helen C Jarnagin, Chanhyuk Park, Heetaek Yang, Noelle N Kosarek, Michael L Whitfield

bioRxiv· August 2023

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Clinical Phenotypes of Patients With Systemic Sclerosis With Distinct Molecular Signatures in Skin.
Monica Yang, Vivien Goh, Jungwha Lee, Monica Espinoza, Yiwei Yuan, Michael L Whitfield

Arthritis Care Res (Hoboken)· July 2023

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CXCL9 Links Skin Inflammation and Fibrosis through CXCR3-Dependent Upregulation of Col1a1 in Fibroblasts.
Jillian M Richmond, Dhrumil Patel, Tomoya Watanabe, Henry W Chen, Viktor Martyanov, Michael L Whitfield

J Invest Dermatol· July 2023

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Senescent Cells Accumulate in Systemic Sclerosis Skin.
Bo Shi, Pei-Suen Tsou, Feiyang Ma, Michael P Mariani, Megan N Mattichak, Michael L Whitfield

J Invest Dermatol· April 2023

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Advances in biological and targeted therapies for systemic sclerosis.
Erica Mulcaire-Jones, Andrea Hsiu Ling Low, Robyn Domsic, Michael L Whitfield, Dinesh Khanna

Expert Opin Biol Ther· April 2023

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Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation.
Jonathan JH Bray, Mazhar Warraich, Michael G Whitfield, Christina Udani Peter, Ranu Baral

Cochrane Database Syst Rev· March 2023

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Human dermal fibroblast-derived exosomes induce macrophage activation in systemic sclerosis.
Rajan Bhandari, Heetaek Yang, Noelle N Kosarek, Avi E Smith, Jonathan A Garlick, Michael L Whitfield

Rheumatology (Oxford)· February 2023

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A genomic meta-analysis of clinical variables and their association with intrinsic molecular subsets in systemic sclerosis.
Jennifer M Franks, Diana M Toledo, Viktor Martyanov, Yue Wang, Suiyuan Huang, Michael L Whitfield

Rheumatology (Oxford)· December 2022

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Machine-learning classification identifies patients with early systemic sclerosis as abatacept responders via CD28 pathway modulation.
Bhaven K Mehta, Monica E Espinoza, Jennifer M Franks, Yiwei Yuan, Yue Wang, Michael L Whitfield

JCI Insight· December 2022

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Self-Assembled Human Skin Equivalents Model Macrophage Activation of Cutaneous Fibrogenesis in Systemic Sclerosis.
Mengqi Huang, Avi Smith, Matthew Watson, Rajan Bhandari, Lauren M Baugh, Michael L Whitfield

Arthritis Rheumatol· July 2022

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Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial.
Lorinda Chung, Cathie Spino, Richard McLain, Sindhu R Johnson, Christopher P Denton, Michael L Whitfield

Lancet Rheumatol· December 2020

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