Publications by authors named "Michele Azada"

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Alectinib induced CNS radiation necrosis in an ALK+NSCLC patient with a remote (7 years) history of brain radiation.
Sai-Hong Ignatius Ou, Michael Weitz, John R Jalas, Daniel F Kelly, Vanessa Wong, Michele C Azada

Lung Cancer· June 2016

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ALK F1174V mutation confers sensitivity while ALK I1171 mutation confers resistance to alectinib. The importance of serial biopsy post progression.
Sai-Hong Ou, Jeffrey C Milliken, Michele C Azada, Vincent A Miller, Siraj M Ali

Lung Cancer· January 2016

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Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling.
Sai-Hong Ignatius Ou, Zachary R Chalmers, Michele C Azada, Jeffrey S Ross, Philip J Stephens

Lung Cancer· June 2015

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Radiation necrosis presenting as pseudoprogression (PsP) during alectinib treatment of previously radiated brain metastases in ALK-positive NSCLC: Implications for disease assessment and management.
Sai-Hong Ignatius Ou, Samuel J Klempner, Michele C Azada, Veronica Rausei-Mills, Christopher Duma

Lung Cancer· June 2015

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I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib.
Sai-Hong Ignatius Ou, Joel Greenbowe, Ziad U Khan, Michele C Azada, Jeffrey S Ross

Lung Cancer· May 2015

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Choroidal metastasis response to crizotinib in a ROS1-rearranged NSCLC patient.
Stephanie Lu, Michele C Azada, Sai-Hong Ignatius Ou

Lung Cancer· February 2015

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Alectinib induces a durable (>15 months) complete response in an ALK-positive non-small cell lung cancer patient who progressed on crizotinib with diffuse leptomeningeal carcinomatosis.
Sai-Hong Ignatius Ou, Karen R Sommers, Michele C Azada, Edward B Garon

Oncologist· February 2015

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Identification of a novel HIP1-ALK fusion variant in Non-Small-Cell Lung Cancer (NSCLC) and discovery of ALK I1171 (I1171N/S) mutations in two ALK-rearranged NSCLC patients with resistance to Alectinib.
Sai-Hong Ignatius Ou, Samuel J Klempner, Joel R Greenbowe, Michele Azada, Alexa B Schrock

J Thorac Oncol· December 2014

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Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.
Shirish M Gadgeel, Leena Gandhi, Gregory J Riely, Alberto A Chiappori, Howard L West, Michele C Azada

Lancet Oncol· September 2014

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Next-generation sequencing reveals a Novel NSCLC ALK F1174V mutation and confirms ALK G1202R mutation confers high-level resistance to alectinib (CH5424802/RO5424802) in ALK-rearranged NSCLC patients who progressed on crizotinib.
Sai-Hong Ignatius Ou, Michele Azada, David J Hsiang, June M Herman, Tatiana S Kain

J Thorac Oncol· April 2014

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Heart rate decrease during crizotinib treatment and potential correlation to clinical response.
Sai-Hong Ignatius Ou, Wilson P Tong, Michele Azada, Christina Siwak-Tapp, Joni Dy

Cancer· June 2013

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Asymptomatic profound sinus bradycardia (heart rate ≤45) in non-small cell lung cancer patients treated with crizotinib.
Sai-Hong Ignatius Ou, Michele Azada, Joni Dy, Jonathan A Stiber

J Thorac Oncol· December 2011

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