Publications by authors named "Michele Modugno"

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Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors.
Giovanni Cervi, Roberto D'Alessio, Simona Bindi, Laura Buffa, Alessia Burocchi, Michele Modugno

Eur J Med Chem· April 2024

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Mcl-1 antagonism is a potential therapeutic strategy in a subset of solid cancers.
Michele Modugno, Patrizia Banfi, Fabio Gasparri, Robert Borzilleri, Percy Carter

Exp Cell Res· March 2015

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Optimization of diarylthiazole B-raf inhibitors: identification of a compound endowed with high oral antitumor activity, mitigated hERG inhibition, and low paradoxical effect.
Maurizio Pulici, Gabriella Traquandi, Chiara Marchionni, Michele Modugno, Rosita Lupi

ChemMedChem· February 2015

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New resistance mechanisms for small molecule kinase inhibitors of Abl kinase.
Michele Modugno

Drug Discov Today Technol· March 2014

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Fault-tolerant almost exact state transmission.
Zhao-Ming Wang, Lian-Ao Wu, Michele Modugno, Wang Yao, Bin Shao

Sci Rep· November 2013

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Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists.
Gretchen M Schroeder, Donna Wei, Patrizia Banfi, Zhen-Wei Cai, Jonathan Lippy, Michele Modugno

Bioorg Med Chem Lett· June 2012

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Identification of a phenylacylsulfonamide series of dual Bcl-2/Bcl-xL antagonists.
Heidi L Perez, Patrizia Banfi, Jay Bertrand, Zhen-Wei Cai, James W Grebinski, Michele Modugno

Bioorg Med Chem Lett· June 2012

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Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase.
Claudia Perrera, Riccardo Colombo, Barbara Valsasina, Patrizia Carpinelli, Sonia Troiani, Michele Modugno

J Biol Chem· April 2010

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Anderson localization of a non-interacting Bose-Einstein condensate.
Giacomo Roati, Chiara D'Errico, Leonardo Fallani, Marco Fattori, Chiara Fort, Giovanni Modugno, Michele Modugno

Nature· June 2008

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Crystal structure of the T315I Abl mutant in complex with the aurora kinases inhibitor PHA-739358.
Michele Modugno, Elena Casale, Chiara Soncini, Pamela Rosettani, Riccardo Colombo

Cancer Res· September 2007

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A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors.
Fabrizio Manetti, Giada A Locatelli, Giovanni Maga, Silvia Schenone, Michele Modugno

J Med Chem· June 2006

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Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.
Fabio Carraro, Antonella Naldini, Annalisa Pucci, Giada A Locatelli, Giovanni Maga, Michele Modugno

J Med Chem· March 2006

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p53-dependent downregulation of metastasis-associated laminin receptor.
Michele Modugno, Elda Tagliabue, Elena Ardini, Valeria Berno, Enrico Galmozzi

Oncogene· October 2002

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Identification of a novel function for 67-kDa laminin receptor: increase in laminin degradation rate and release of motility fragments.
Elena Ardini, Barbara Sporchia, Loredano Pollegioni, Michele Modugno, Cristina Ghirelli

Cancer Res· March 2002

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