Publications by authors named "Michelle Gleave"

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A single-center, open-label study investigating the excretion balance, pharmacokinetics, metabolism, and absolute bioavailability of a single oral dose of [C]-labeled idasanutlin and an intravenous tracer dose of [C]-labeled idasanutlin in a single cohort of patients with solid tumors.
Zsuzsanna Pápai, Lin-Chi Chen, Daniel Da Costa, Steven Blotner, Faye Vazvaei, Michelle Gleave

Cancer Chemother Pharmacol· July 2019

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Simultaneous qualitative and quantitative metabolism data generation: a convenient marriage?
Angus N R Nedderman, Mark E Savage, Michelle Gleave, Julian J Haynes

Bioanalysis· May 2012

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The strengths of mass spectrometry are not just sensitivity and selectivity.
Michelle Gleave

Bioanalysis· February 2011

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Excretion and metabolism of lersivirine (5-{[3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a next-generation non-nucleoside reverse transcriptase inhibitor, after administration of [14C]Lersivirine to healthy volunteers.
Manoli Vourvahis, Michelle Gleave, Angus N R Nedderman, Ruth Hyland, Iain Gardner

Drug Metab Dispos· May 2010

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In vitro screening techniques for reactive metabolites for minimizing bioactivation potential in drug discovery.
Chandra Prakash, Raman Sharma, Michelle Gleave, Angus Nedderman

Curr Drug Metab· November 2008

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Evolution of an open-access quantitative bioanalytical mass spectrometry service in a drug discovery environment.
Patricia Wright, Christophe Chassaing, Nigel Cussans, Drew Gibson, Caroline Green, Michelle Gleave

Biomed Chromatogr· August 2006

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