Publications by authors named "Mike Hayashi"

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Albumin-Mediated Uptake Improves Human Clearance Prediction for Hepatic Uptake Transporter Substrates Aiding a Mechanistic In Vitro-In Vivo Extrapolation (IVIVE) Strategy in Discovery Research.
Na Li, Akshay Badrinarayanan, Kazuya Ishida, Xingwen Li, John Roberts, Mike Hayashi

AAPS J· November 2020

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Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes.
Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi

Drug Metab Dispos· October 2020

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Enhanced detection and characterization of glutathione-trapped reactive metabolites by pseudo-MS(3) transition using a linear ion trap mass spectrometer.
Xiaochun Zhu, Mike Hayashi, Raju Subramanian

Chem Res Toxicol· September 2012

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Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs.
Yang Xu, Yihong Zhou, Mike Hayashi, Magang Shou, Gary L Skiles

Drug Metab Dispos· July 2011

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In vitro metabolism of the novel, highly selective oral angiogenesis inhibitor motesanib diphosphate in preclinical species and in humans.
Chun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi

Drug Metab Dispos· July 2009

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Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction.
Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey

Drug Metab Dispos· November 2008

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