Publications by authors named "Mikhail Hammond"

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Precision-activated T-cell engagers targeting HER2 or EGFR and CD3 mitigate on-target, off-tumor toxicity for immunotherapy in solid tumors.
Fiore Cattaruzza, Ayesha Nazeer, Milton To, Mikhail Hammond, Caitlin Koski

Nat Cancer· April 2023

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Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs.
K C Nicolaou, Santhosh Reddy Rekula, S Mothish Kumar, Ananda Rao Podilapu, Ryan P Matuszak, Mikhail Hammond

J Org Chem· February 2021

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Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis.
K C Nicolaou, Saiyong Pan, Kiran K Pulukuri, Qiuji Ye, Stephan Rigol, Mikhail Hammond

J Org Chem· February 2021

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Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues.
K C Nicolaou, Yogesh G Shelke, Balu D Dherange, Aaron Kempema, Baiwei Lin, Mikhail Hammond

J Org Chem· March 2020

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Total Synthesis and Biological Evaluation of Tiancimycins A and B, Yangpumicin A, and Related Anthraquinone-Fused Enediyne Antitumor Antibiotics.
K C Nicolaou, Dipendu Das, Yong Lu, Subhrajit Rout, Emmanuel N Pitsinos, Mikhail Hammond

J Am Chem Soc· February 2020

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