Publications by authors named "Mikhail Levit"

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Basic Science and Pathogenesis.
Aurore Delvenne, Marianna Rizzo, Bailin Zhang, Mikhail Levit, Henrik Zetterberg

Alzheimers Dement· December 2025

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Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis.
Matija Zelic, Anna Blazier, Fabrizio Pontarelli, Michael LaMorte, Jeremy Huang, Mikhail Levit

Immunity· April 2025

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Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.
Wanwisa Promsote, Ling Xu, Jason Hataye, Giulia Fabozzi, Kylie March, Mikhail Levit

Nat Commun· June 2023

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Publisher Correction: A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Edward Seung, Zhen Xing, Lan Wu, Ercole Rao, Virna Cortez-Retamozo, Mikhail Levit

Nature· April 2022

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A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Edward Seung, Zhen Xing, Lan Wu, Ercole Rao, Virna Cortez-Retamozo, Mikhail Levit

Nature· March 2022

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Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Christian Hotz, Timothy R Wagenaar, Friederike Gieseke, Dinesh S Bangari, Michelle Callahan, Mikhail Levit

Sci Transl Med· September 2021

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SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models.
Maysoun Shomali, Jane Cheng, Fangxian Sun, Malvika Koundinya, Zhuyan Guo, Mikhail N Levit

Mol Cancer Ther· February 2021

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Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model.
Claude Barberis, Paul Erdman, Mark Czekaj, Luke Fire, James Pribish, Mikhail Levit

Bioorg Med Chem Lett· December 2020

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Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade.
Rita Greco, Hongjing Qu, Hui Qu, Joachim Theilhaber, Gary Shapiro, Mikhail Levit

Oncoimmunology· September 2020

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Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer.
Youssef El-Ahmad, Michel Tabart, Frank Halley, Victor Certal, Fabienne Thompson, Mikhail Levit

J Med Chem· January 2020

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Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors - Lead optimization - Part III.
Claude Barberis, James Pribish, Elina Tserlin, Alexandre Gross, Mark Czekaj, Mikhail Levit

Bioorg Med Chem Lett· February 2019

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Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation.
Zhihu Ding, Chaomei Shi, Lan Jiang, Tatiana Tolstykh, Hui Cao, Mikhail Levit

Oncotarget· December 2017

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Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification - Part II.
Claude Barberis, Neil Moorcroft, James Pribish, Elina Tserlin, Alexandre Gross, Mikhail Levit

Bioorg Med Chem Lett· October 2017

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Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I.
Claude Barberis, Neil Moorcroft, Chris Arendt, Mikhail Levit, Sandra Moreno-Mazza

Bioorg Med Chem Lett· October 2017

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Concomitant Inhibition of PI3Kβ and BRAF or MEK in PTEN-Deficient/BRAF-Mutant Melanoma Treatment: Preclinical Assessment of SAR260301 Oral PI3Kβ-Selective Inhibitor.
Hélène Bonnevaux, Olivier Lemaitre, Loic Vincent, Mikhail N Levit, Fanny Windenberger

Mol Cancer Ther· July 2016

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PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.
Zhuyan Guo, Anlai Wang, Weidong Zhang, Mikhail Levit, Qiang Gao

Blood· September 2014

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Use of carboxylated cellulose nanofibrils-filled magnetic chitosan hydrogel beads as adsorbents for Pb(II).
Yiming Zhou, Shiyu Fu, Liangliang Zhang, Huaiyu Zhan, Mikhail V Levit

Carbohydr Polym· January 2014

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SAR103168: a tyrosine kinase inhibitor with therapeutic potential in myeloid leukemias.
Bernard Bourrié, Diana L Brassard, Sylvie Cosnier-Pucheu, Asher Zilberstein, Kin Yu, Mikhail Levit

Leuk Lymphoma· July 2013

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Organization of the receptor-kinase signaling array that regulates Escherichia coli chemotaxis.
Mikhail N Levit, Thorsten W Grebe, Jeffry B Stock

J Biol Chem· September 2002

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Subunit organization in a soluble complex of tar, CheW, and CheA by electron microscopy.
Noreen R Francis, Mikhail N Levit, Tanvir R Shaikh, Linda A Melanson, Jeffry B Stock

J Biol Chem· September 2002

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Receptor methylation controls the magnitude of stimulus-response coupling in bacterial chemotaxis.
Mikhail N Levit, Jeffry B Stock

J Biol Chem· September 2002

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Information processing in bacterial chemotaxis.
Jeffry B Stock, Mikhail N Levit, Peter M Wolanin

Sci STKE· May 2002

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Interactions between Escherichia coli nucleoside-diphosphate kinase and DNA.
Mikhail N Levit, Bozena M Abramczyk, Jeffry B Stock, Edith H Postel

J Biol Chem· February 2002

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