Publications by authors named "Milan Fabry"

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CDK2-based CDK7 mimic as a tool for structural analysis: Biochemical validation and crystal structure with SY5609.
Jana Škerlová, Veronika Krejčiříková, Miroslav Peřina, Veronika Vojáčková, Milan Fábry

Int J Biol Macromol· March 2025

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Using environment-sensitive tetramethylated thiophene-BODIPY fluorophores in DNA probes for studying effector-induced conformational changes of protein-DNA complexes.
Markéta Šoltysová, Pedro Güixens-Gallardo, Irena Sieglová, Anna Soldánová, Veronika Krejčiříková

RSC Chem Biol· March 2025

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Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function.
Markéta Šoltysová, Jana Škerlová, Petr Pachl, Karel Škubník, Milan Fábry

Nucleic Acids Res· July 2024

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An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans.
Zuzana Matoušková, Katarína Orsághová, Pavel Srb, Jana Pytelková, Zdeněk Kukačka

Int J Mol Sci· February 2024

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Tumor-specific targeting of polymer drug delivery systems with recombinant proteins bound via tris(nitrilotriacetic acid).
Michal Pechar, Vlastimil Král, Lucie Kracíková, Ladislav Androvič, Eliška Hrdá

Int J Pharm· December 2023

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Multivalency of nucleosome recognition by LEDGF.
Eliška Koutná, Vanda Lux, Tomáš Kouba, Jana Škerlová, Jiří Nováček

Nucleic Acids Res· October 2023

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Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
Jan Skácel, Stefan Djukic, Ondřej Baszczyňski, Filip Kalčic, Tadeáš Bílek

J Med Chem· May 2023

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Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family.
Markéta Šoltysová, Irena Sieglová, Milan Fábry, Jiří Brynda, Jana Škerlová

Acta Crystallogr D Struct Biol· November 2021

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A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Katerina Cermakova, Jonas Demeulemeester, Vanda Lux, Monika Nedomova, Seth R Goldman, Milan Fabry

Science· November 2021

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Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells.
Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Celeste Abreu, Kateřina Krejčová

Biomedicines· November 2021

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Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.
Michael Kugler, Jan Nekvinda, Josef Holub, Suzan El Anwar, Viswanath Das

Chembiochem· September 2021

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Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
Bohumír Grüner, Michael Kugler, Suzan El Anwar, Josef Holub, Jan Nekvinda

Chempluschem· March 2021

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Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
Bohumír Grüner, Michael Kugler, Suzan El Anwar, Josef Holub, Jan Nekvinda

Chempluschem· March 2021

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N-Glycosylation can selectively block or foster different receptor-ligand binding modes.
Joni Vuorio, Jana Škerlová, Milan Fábry, Václav Veverka, Ilpo Vattulainen

Sci Rep· March 2021

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Molecular Mechanism of LEDGF/p75 Dimerization.
Vanda Lux, Tine Brouns, Kateřina Čermáková, Pavel Srb, Milan Fábry

Structure· December 2020

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The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX.
Michael Kugler, Josef Holub, Jiří Brynda, Klára Pospíšilová, Suzan El Anwar

J Enzyme Inhib Med Chem· December 2020

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Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
Jana Dvořanová, Michael Kugler, Josef Holub, Václav Šícha, Viswanath Das

Eur J Med Chem· August 2020

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Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
Kateřina Macháčková, Květoslava Mlčochová, Pavlo Potalitsyn, Kateřina Hanková, Ondřej Socha

J Biol Chem· November 2019

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Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX.
Bohumír Grüner, Jiří Brynda, Viswanath Das, Václav Šícha, Jana Štěpánková

J Med Chem· November 2019

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Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site.
Petr Man, Milan Fábry, Irena Sieglová, Daniel Kavan, Petr Novák

Biochim Biophys Acta Proteins Proteom· April 2019

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Polymer Cancerostatics Targeted by Recombinant Antibody Fragments to GD2-Positive Tumor Cells.
Robert Pola, Vlastimil Král, Sergey K Filippov, Leonid Kaberov, Tomáš Etrych

Biomacromolecules· January 2019

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Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Subhalakshmi Sharma, Kateřina Čermáková, Jan De Rijck, Jonas Demeulemeester, Milan Fábry

Proc Natl Acad Sci U S A· July 2018

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Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Aleš Hnízda, Milan Fábry, Takaya Moriyama, Petr Pachl, Michael Kugler

Leukemia· June 2018

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A new approach to CAR T-cell gene engineering and cultivation using piggyBac transposon in the presence of IL-4, IL-7 and IL-21.
Pavlína Ptáčková, Jan Musil, Martin Štach, Petr Lesný, Šárka Němečková

Cytotherapy· April 2018

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Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation.
Kateřina Macháčková, Martina Chrudinová, Jelena Radosavljević, Pavlo Potalitsyn, Květoslava Křížková

Biochemistry· April 2018

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