Publications by authors named "Miles Piper"

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IL15/IL15Ra complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to expand progenitor TCF1+ CD8 T cells.
Miles Piper, Chloe A Hodgson, Jacob Gadwa, Maureen Hoen, Michael W Knitz

Mol Cancer Ther· September 2025

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Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment.
Jacob Gadwa, Justin Yu, Miles Piper, Michael W Knitz, Laurel B Darragh

J Immunother Cancer· January 2025

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IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells.
Miles Piper, Jacob Gadwa, Chloe Hodgson, Michael Knitz, Elliott Yee

bioRxiv· September 2024

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Publisher Correction: A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Laurel B Darragh, Michael M Knitz, Junxiao Hu, Eric T Clambey, Jennifer Backus, Miles Piper

Nat Cancer· January 2024

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Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Jesus Amo-Aparicio, Adrian Dominguez, Shaikh M Atif, Alberto Dinarello, Tania Azam, Miles Piper

Cancer Res Commun· September 2023

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Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC.
Jacob Gadwa, Maria Amann, Thomas E Bickett, Michael W Knitz, Laurel B Darragh, Miles Piper

Cell Rep Med· August 2023

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Vasculitis, CA19-9, and Perineural Invasion Differentially Predict Response and Surgical Outcome in Pancreatic Ductal Adenocarcinoma.
Miles Piper, Richard Blake Ross, Junxiao Hu, Shuichi Watanabe, Michael Knitz

Int J Radiat Oncol Biol Phys· July 2023

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Immune Resistance Mechanisms and the Road to Personalized Immunotherapy.
Miles Piper, Harriet Kluger, Eytan Ruppin, Siwen Hu-Lieskovan

Am Soc Clin Oncol Educ Book· June 2023

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Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis.
Miles Piper, Maureen Hoen, Laurel B Darragh, Michael W Knitz, Diemmy Nguyen

Cancer Cell· May 2023

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Author Correction: A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Laurel B Darragh, Michael M Knitz, Junxiao Hu, Eric T Clambey, Jennifer Backus, Miles Piper

Nat Cancer· January 2023

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A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Laurel B Darragh, Michael M Knitz, Junxiao Hu, Eric T Clambey, Jennifer Backus, Miles Piper

Nat Cancer· November 2022

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EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Shilpa Bhatia, Diemmy Nguyen, Laurel B Darragh, Benjamin Van Court, Jaspreet Sharma, Miles Piper

Nat Commun· June 2022

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Loss of cancer cell STAT1 improves response to radiation therapy and promotes T cell activation in head and neck squamous cell carcinoma.
Michael W Knitz, Laurel B Darragh, Thomas E Bickett, Shilpa Bhatia, Sanjana Bukkapatnam, Miles Piper

Cancer Immunol Immunother· May 2022

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Dichotomous effects of cellular expression of STAT3 on tumor growth of HNSCC.
Thomas E Bickett, Michael W Knitz, Miles Piper, Ayman J Oweida, Jacob Gadwa

Mol Ther· March 2022

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Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma.
Miles Piper, Benjamin Van Court, Adam Mueller, Shuichi Watanabe, Thomas Bickett

Clin Cancer Res· March 2022

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FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC.
Thomas E Bickett, Michael Knitz, Laurel B Darragh, Shilpa Bhatia, Benjamin Van Court, Miles Piper

Clin Cancer Res· November 2021

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Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.
Adam C Mueller, Miles Piper, Andrew Goodspeed, Shiv Bhuvane, Jason S Williams

Cancer Res· June 2021

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Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide.
Ayman J Oweida, Adam C Mueller, Miles Piper, Dallin Milner, Benjamin Van Court

Cancer Immunol Immunother· April 2021

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Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis.
Michael W Knitz, Thomas E Bickett, Laurel B Darragh, Ayman J Oweida, Shilpa Bhatia, Miles Piper

J Immunother Cancer· April 2021

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Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer.
Jacob Gadwa, Thomas E Bickett, Laurel B Darragh, Michael William Knitz, Shilpa Bhatia, Miles Piper

J Immunother Cancer· March 2021

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The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.
Shilpa Bhatia, Sanjana Bukkapatnam, Benjamin Van Court, Andy Phan, Ayman Oweida, Miles Piper

Mol Carcinog· September 2020

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The interplay between cancer associated fibroblasts and immune cells in the context of radiation therapy.
Miles Piper, Adam C Mueller, Sana D Karam

Mol Carcinog· July 2020

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