Publications by authors named "Miljan Simonovic"

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Structural basis of Cas9 DNA interrogation with a 5' truncated sgRNA.
Kaitlyn A Kiernan, Jieun Kwon, Bradley J Merrill, Miljan Simonović

Nucleic Acids Res· January 2025

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Human selenocysteine synthase, SEPSECS, has evolved to optimize binding of a tRNA-based substrate.
Anupama K Puppala, Dylan Sosa, Jennifer Castillo Suchkou, Rachel L French, Malgorzata Dobosz-Bartoszek

Nucleic Acids Res· November 2024

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De novo missense variants in exon 9 of SEPHS1 cause a neurodevelopmental condition with developmental delay, poor growth, hypotonia, and dysmorphic features.
Sureni V Mullegama, Kaitlyn A Kiernan, Erin Torti, Ethan Pavlovsky, Nicholas Tilton

Am J Hum Genet· June 2024

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De novo missense variants in exon 9 of SEPHS1 cause a neurodevelopmental condition with developmental delay, poor growth, hypotonia, and dysmorphic features.
Sureni V Mullegama, Kaitlyn A Kiernan, Erin Torti, Ethan Pavlovsky, Nicholas Tilton

Am J Hum Genet· April 2024

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Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Anupama K Puppala, Jennifer Castillo Suchkou, Rachel L French, Kaitlyn A Kiernan, Miljan Simonović

Nucleic Acids Res· May 2023

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Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Tarek Hilal, Benjamin Y Killam, Milica Grozdanović, Malgorzata Dobosz-Bartoszek, Justus Loerke

Science· June 2022

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Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Xing Zhu, Ryan Clarke, Anupama K Puppala, Sagar Chittori, Alan Merk

Nat Struct Mol Biol· August 2019

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Human aminoacyl-tRNA synthetases in diseases of the nervous system.
Jana Ognjenović, Miljan Simonović

RNA Biol· November 2018

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On elongation factor eEFSec, its role and mechanism during selenium incorporation into nascent selenoproteins.
Miljan Simonović, Anupama K Puppala

Biochim Biophys Acta Gen Subj· November 2018

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Insights into substrate promiscuity of human seryl-tRNA synthetase.
Kaitlyn M Holman, Anupama K Puppala, Jonathan W Lee, Hyun Lee, Miljan Simonović

RNA· November 2017

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Selenoprotein Gene Nomenclature.
Vadim N Gladyshev, Elias S Arnér, Marla J Berry, Regina Brigelius-Flohé, Elspeth A Bruford

J Biol Chem· November 2016

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Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Malgorzata Dobosz-Bartoszek, Mark H Pinkerton, Zbyszek Otwinowski, Srinivas Chakravarthy, Dieter Söll

Nat Commun· October 2016

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Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Anupama K Puppala, Rachel L French, Doreen Matthies, Ulrich Baxa, Sriram Subramaniam

Sci Rep· August 2016

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The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Jana Ognjenović, Jiang Wu, Doreen Matthies, Ulrich Baxa, Sriram Subramaniam

Nucleic Acids Res· April 2016

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The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA.
Kaitlyn M Holman, Jiang Wu, Jiqiang Ling, Miljan Simonović

Nucleic Acids Res· February 2016

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Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Donald Gagné, Rachel L French, Chitra Narayanan, Miljan Simonović, Pratul K Agarwal

Structure· December 2015

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Selenoprotein biosynthesis defect causes progressive encephalopathy with elevated lactate.
Anna-Kaisa Anttonen, Taru Hilander, Tarja Linnankivi, Pirjo Isohanni, Rachel L French

Neurology· July 2015

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Interactions of epigallo-catechin 3-gallate and ovalbumin, the major allergen of egg white.
Jana Ognjenović, Marija Stojadinović, Miloš Milčić, Danijela Apostolović, Jelena Vesić

Food Chem· December 2014

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Structural asymmetry of the terminal catalytic complex in selenocysteine synthesis.
Rachel L French, Nirupama Gupta, Paul R Copeland, Miljan Simonović

J Biol Chem· October 2014

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The synthesis of methylated, phosphorylated, and phosphonated 3'-aminoacyl-tRNA(Sec) mimics.
Lukas Rigger, Rachel L Schmidt, Kaitlyn M Holman, Miljan Simonović, Ronald Micura

Chemistry· November 2013

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Synthesis and decoding of selenocysteine and human health.
Rachel L Schmidt, Miljan Simonović

Croat Med J· December 2012

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The mechanism of pre-transfer editing in yeast mitochondrial threonyl-tRNA synthetase.
Jiqiang Ling, Kaitlyn M Peterson, Ivana Simonovic, Dieter Söll, Miljan Simonovic

J Biol Chem· August 2012

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Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Jiqiang Ling, Kaitlyn M Peterson, Ivana Simonović, Chris Cho, Dieter Söll

Proc Natl Acad Sci U S A· February 2012

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An unusual tRNAThr derived from tRNAHis reassigns in yeast mitochondria the CUN codons to threonine.
Dan Su, Allyson Lieberman, B Franz Lang, Miljan Simonovic, Dieter Söll

Nucleic Acids Res· June 2011

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Human SepSecS or SLA/LP: selenocysteine formation and autoimmune hepatitis.
Sotiria Palioura, Johannes Herkel, Miljan Simonović, Ansgar W Lohse, Dieter Söll

Biol Chem· July 2010

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