Publications by authors named "Miriam Verwei"

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The effect of chitosan on the bioaccessibility and intestinal permeability of acyclovir.
Marlies Kubbinga, Patrick Augustijns, Mauricio A García, Christian Heinen, Heleen M Wortelboer, Miriam Verwei

Eur J Pharm Biopharm· March 2019

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Evaluation of two dynamic in vitro models simulating fasted and fed state conditions in the upper gastrointestinal tract (TIM-1 and tiny-TIM) for investigating the bioaccessibility of pharmaceutical compounds from oral dosage forms.
Miriam Verwei, Mans Minekus, Evelijn Zeijdner, Ronald Schilderink, Robert Havenaar

Int J Pharm· February 2016

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Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling.
Jochem Louisse, Sieto Bosgra, Bas J Blaauboer, Ivonne M C M Rietjens, Miriam Verwei

Arch Toxicol· July 2015

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Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.
Sieto Bosgra, Evita van de Steeg, Maria L Vlaming, Kitty C Verhoeckx, Maarten T Huisman, Miriam Verwei

Eur J Pharm Sci· December 2014

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A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices.
Joost Westerhout, Evita van de Steeg, Dimitri Grossouw, Evelijn E Zeijdner, Cyrille A M Krul, Miriam Verwei

Eur J Pharm Sci· October 2014

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In vitro models for the prediction of in vivo performance of oral dosage forms.
Edmund S Kostewicz, Bertil Abrahamsson, Marcus Brewster, Joachim Brouwers, James Butler, Miriam Verwei

Eur J Pharm Sci· June 2014

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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Miriam Verwei

Arch Toxicol· January 2013

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Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation.
Jochem Louisse, Miriam Verwei, Ruud A Woutersen, Bas J Blaauboer, Ivonne M C M Rietjens

Expert Opin Drug Metab Toxicol· January 2012

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Relative developmental toxicity potencies of retinoids in the embryonic stem cell test compared with their relative potencies in in vivo and two other in vitro assays for developmental toxicity.
Jochem Louisse, Süleyman Gönen, Ivonne M C M Rietjens, Miriam Verwei

Toxicol Lett· May 2011

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The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man.
Jochem Louisse, Esther de Jong, Johannes J M van de Sandt, Bas J Blaauboer, Ruud A Woutersen, Miriam Verwei

Toxicol Sci· December 2010

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Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites.
Jochem Louisse, Yanqing Bai, Miriam Verwei, Johannes J M van de Sandt, Bas J Blaauboer

Toxicol Appl Pharmacol· June 2010

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Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared with the in vivo potency of their parent compounds.
Esther de Jong, Jochem Louisse, Miriam Verwei, Bas J Blaauboer, Johannes J M van de Sandt

Toxicol Sci· July 2009

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A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop.
Philip Marx-Stoelting, Els Adriaens, Hans-Jürgen Ahr, Susanne Bremer, Bernward Garthoff, Miriam Verwei

Altern Lab Anim· July 2009

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Predicted serum folate concentrations based on in vitro studies and kinetic modeling are consistent with measured folate concentrations in humans.
Miriam Verwei, Andreas P Freidig, Robert Havenaar, John P Groten

J Nutr· December 2006

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Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling.
Miriam Verwei, Johan A van Burgsteden, Cyrille A M Krul, Johannes J M van de Sandt, Andreas P Freidig

Toxicol Lett· August 2006

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Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells.
Miriam Verwei, Henk van den Berg, Robert Havenaar, John P Groten

Eur J Nutr· June 2005

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The binding of folic acid and 5-methyltetrahydrofolate to folate-binding proteins during gastric passage differs in a dynamic in vitro gastrointestinal model.
Miriam Verwei, Karin Arkbåge, Hans Mocking, Robert Havenaar, John Groten

J Nutr· January 2004

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Bioaccessibility of folic acid and (6S)-5-methyltetrahydrofolate decreases after the addition of folate-binding protein to yogurt as studied in a dynamic in vitro gastrointestinal model.
Karin Arkbåge, Miriam Verwei, Robert Havenaar, Cornelia Witthöft

J Nutr· November 2003

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Folic acid and 5-methyltetrahydrofolate in fortified milk are bioaccessible as determined in a dynamic in vitro gastrointestinal model.
Miriam Verwei, Karin Arkbåge, Robert Havenaar, Henk van den Berg, Cornelia Witthöft

J Nutr· July 2003

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