Publications by authors named "Mirja Rotinen"

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ONECUT2: a validated drug target and lineage plasticity driver in prostate cancer and other malignancies.
Michael R Freeman, Lillian M Perez, Qian Yang, Chen Qian, Ramachandran Murali, Mirja Rotinen

Endocr Relat Cancer· November 2025

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ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer.
Mirian Gutiérrez, Irene Zamora, Raquel Iriarte, María José Pajares, Qian Yang, Mirja Rotinen

Mol Med· June 2025

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ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity.
Irene Zamora, Mirian Gutiérrez, Alex Pascual, María J Pajares, Miguel Barajas, Mirja Rotinen

Cell Oncol (Dordr)· February 2025

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ONECUT2 acts as a lineage plasticity driver in adenocarcinoma as well as neuroendocrine variants of prostate cancer.
Chen Qian, Qian Yang, Mirja Rotinen, Rongrong Huang, Hyoyoung Kim

Nucleic Acids Res· July 2024

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Actionable Driver Events in Small Cell Lung Cancer.
Mirian Gutiérrez, Irene Zamora, Michael R Freeman, Ignacio J Encío, Mirja Rotinen

Int J Mol Sci· December 2023

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ONECUT2 Activates Diverse Resistance Drivers of Androgen Receptor-Independent Heterogeneity in Prostate Cancer.
Chen Qian, Qian Yang, Mirja Rotinen, Rongrong Huang, Hyoyoung Kim

bioRxiv· October 2023

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Targeting Key Players of Neuroendocrine Differentiation in Prostate Cancer.
Irene Zamora, Michael R Freeman, Ignacio J Encío, Mirja Rotinen

Int J Mol Sci· September 2023

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Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer.
Julie Suan-Wei Yang, Chen Qian, Sungyong You, Mirja Rotinen, Edwin M Posadas

Am J Clin Exp Urol· August 2021

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Cutting down on lung cancer: Ecliptasaponin A is a novel therapeutic agent.
Mirja Rotinen, Ignacio Encío

Ann Transl Med· July 2020

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27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells.
Shweta Dambal, Mahmoud Alfaqih, Sergio Sanders, Erick Maravilla, Adela Ramirez-Torres, Mirja Rotinen

Mol Cancer Res· May 2020

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"Defining the Independence of the Liver Circadian Clock" & "BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis".
Mirja Rotinen

Front Neurosci· February 2020

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ONECUT2 as a new therapeutic target in androgen receptor-indifferent prostate cancer.
Michael R Freeman, Mirja Rotinen, Sungyong You

Transl Cancer Res· November 2019

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Meeting report: Metastasis Research Society (MRS) 17th Biennial conference and associated Young Investigator Satellite Meeting (YISM) on cancer metastasis.
Thomas Beadnell, Lucia Borriello, Jessica Christenson, Jaime Fornetti, Ian Guldner, Mirja Rotinen

Clin Exp Metastasis· April 2019

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ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.
Mirja Rotinen, Sungyong You, Julie Yang, Simon G Coetzee, Mariana Reis-Sobreiro

Nat Med· December 2018

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Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.
Mariana Reis-Sobreiro, Jie-Fu Chen, Tatiana Novitskaya, Sungyong You, Samantha Morley, Mirja Rotinen

Cancer Res· November 2018

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Changes in gene expression profiling of apoptotic genes in neuroblastoma cell lines upon retinoic acid treatment.
Jon Celay, Idoia Blanco, Paula Lázcoz, Mirja Rotinen, Javier S Castresana

PLoS One· November 2013

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Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.
Dolores Di Vizio, Matteo Morello, Andrew C Dudley, Peter W Schow, Rosalyn M Adam, Mirja Rotinen

Am J Pathol· November 2012

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Regulation of 17β-hydroxysteroid dehydrogenases in cancer: regulating steroid receptor at pre-receptor stage.
Mirja Rotinen, Joaquín Villar, Ignacio Encío

J Physiol Biochem· September 2012

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Transcriptional regulation of type 11 17β-hydroxysteroid dehydrogenase expression in prostate cancer cells.
Mirja Rotinen, Joaquín Villar, Jon Celay, Irantzu Serrano, Vicente Notario

Mol Cell Endocrinol· June 2011

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Type 10 17β-hydroxysteroid dehydrogenase expression is regulated by C/EBPβ in HepG2 cells.
Mirja Rotinen, Joaquín Villar, Jon Celay, Ignacio Encío

J Steroid Biochem Mol Biol· October 2010

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Estradiol induces type 8 17beta-hydroxysteroid dehydrogenase expression: crosstalk between estrogen receptor alpha and C/EBPbeta.
Mirja Rotinen, Jon Celay, Marta M Alonso, Aranzazu Arrazola, Ignacio Encio

J Endocrinol· January 2009

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Transcriptional regulation of the human type 8 17beta-hydroxysteroid dehydrogenase gene by C/EBPbeta.
Joaquín Villar, Jon Celay, Marta M Alonso, Mirja Rotinen, Carlos de Miguel

J Steroid Biochem Mol Biol· November 2007

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