Publications by authors named "Mitchell Reff"

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A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity.
Jianying Dong, Arlene Sereno, Dikran Aivazian, Emma Langley, Brian R Miller, Mitchell E Reff

MAbs· December 2011

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Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
Lin Zhang, Junhua Fan, Jer-Hong Chong, Angela Cesena, Betty Y Y Tam, Mitchell Reff

Bioorg Med Chem Lett· September 2011

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Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity.
Jianying Dong, Arlene Sereno, William B Snyder, Brian R Miller, Susan Tamraz, Mitchell Reff

J Biol Chem· February 2011

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Combination of two insulin-like growth factor-I receptor inhibitory antibodies targeting distinct epitopes leads to an enhanced antitumor response.
Jianying Dong, Stephen J Demarest, Arlene Sereno, Susan Tamraz, Emma Langley, Mitchell E Reff

Mol Cancer Ther· September 2010

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Conserved amino acid networks involved in antibody variable domain interactions.
Norman Wang, William F Smith, Brian R Miller, Dikran Aivazian, Alexey A Lugovskoy, Mitchell E Reff

Proteins· July 2009

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Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.
Adam Doern, Xianjun Cao, Arlene Sereno, Christopher L Reyes, Angelina Altshuler, Mitchell E Reff

J Biol Chem· April 2009

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Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Bruno Figueroa, Eric Ailor, Douglas Osborne, J Marie Hardwick, Mitchell Reff

Biotechnol Bioeng· July 2007

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Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy.
Matvey Lukashev, Doreen LePage, Cheryl Wilson, Véronique Bailly, Ellen Garber, Mitchell Reff

Cancer Res· October 2006

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Novel antibody hinge regions for efficient production of CH2 domain-deleted antibodies.
Scott M Glaser, Ina E Hughes, Jennifer R Hopp, Karen Hathaway, Daniel Perret, Mitchell E Reff

J Biol Chem· December 2005

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Anti-CD23 monoclonal antibody, lumiliximab, inhibited allergen-induced responses in antigen-presenting cells and T cells from atopic subjects.
Jill A Poole, Jianfeng Meng, Mitchell Reff, Mary C Spellman, Lanny J Rosenwasser

J Allergy Clin Immunol· October 2005

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Future of monoclonal antibodies in the treatment of hematologic malignancies.
Mitchell E Reff, Kandasamy Hariharan, Gary Braslawsky

Cancer Control· June 2002

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Anti-CD23 monoclonal antibody inhibits germline Cepsilon transcription in B cells.
Shingo Yabuuchi, Takehiko Nakamura, William S Kloetzer, Mitchell E Reff

Int Immunopharmacol· March 2002

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