Publications by authors named "Modassir Choudhry"

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Clinical manufacture of CRISPR/Cas9-based cytokine-induced SH2 protein knock-out tumor-infiltrating lymphocytes for gastrointestinal cancers.
Matthew J Johnson, Darin Sumstad, Timothy D Folsom, Nicholas J Slipek, Anthony P DeFeo, Modassir Choudhry

Cytotherapy· October 2025

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Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial.
Emil Lou, Modassir S Choudhry, Timothy K Starr, Timothy D Folsom, Jason Bell

Lancet Oncol· May 2025

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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates.
Matthew J Johnson, Anthony P DeFeo, Nicholas J Slipek, Timothy D Folsom, Tom Henley, Modassir S Choudhry

J Vis Exp· May 2025

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Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair.
Beau R Webber, Matthew J Johnson, Joseph G Skeate, Nicholas J Slipek, Walker S Lahr, Modassir Choudhry

Nat Biomed Eng· December 2024

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A genetically engineered, stem-cell-derived cellular vaccine.
Amanda Cooper, Adam Sidaway, Abishek Chandrashekar, Elizabeth Latta, Krishnendu Chakraborty, Modassir Choudhry

Cell Rep Med· December 2022

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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Douglas C Palmer, Beau R Webber, Yogin Patel, Matthew J Johnson, Christine M Kariya, Modassir Choudhry

Med· October 2022

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Improved Genome Packaging Efficiency of Adeno-associated Virus Vectors Using Rep Hybrids.
Mario Mietzsch, Courtnee Eddington, Ariana Jose, Jane Hsi, Paul Chipman, Modassir Choudhry

J Virol· September 2021

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Virus Induced Lymphocytes (VIL) as a novel viral antigen-specific T cell therapy for COVID-19 and potential future pandemics.
Rohan Sivapalan, Jinyan Liu, Krishnendu Chakraborty, Elisa Arthofer, Modassir Choudhry

Sci Rep· July 2021

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Adeno-associated Virus (AAV) Capsid Chimeras with Enhanced Infectivity Reveal a Core Element in the AAV Genome Critical for both Cell Transduction and Capsid Assembly.
Lydia Viney, Tilmann Bürckstümmer, Courtnee Eddington, Mario Mietzsch, Modassir Choudhry

J Virol· March 2021

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Excision of an aneurysm of the left atrial appendage.
Parsia A Vagefi, Modassir Choudhry, Alan D Hilgenberg

J Thorac Cardiovasc Surg· March 2007

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