Publications by authors named "Molly Hood"

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Discovery of vimseltinib (DCC-3014), a highly selective CSF1R switch-control kinase inhibitor, in clinical development for the treatment of Tenosynovial Giant Cell Tumor (TGCT).
Timothy M Caldwell, Yu Mi Ahn, Stacie L Bulfer, Cynthia B Leary, Molly M Hood

Bioorg Med Chem Lett· October 2022

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Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors.
Timothy M Caldwell, Michael D Kaufman, Scott C Wise, Yu Mi Ahn, Molly M Hood

Bioorg Med Chem Lett· October 2022

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Collagen and soy peptides attenuate contractile loss from UVA damage and enhance the antioxidant capacity of dermal fibroblasts.
Sophia Y Zhang, Molly Hood, Iris X Zhang, Clark L Chen, Lynn L Zhang

J Cosmet Dermatol· July 2021

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The combination of wheat peptides and fucoidan protects against chronic superficial gastritis and alters gut microbiota: a double-blinded, placebo-controlled study.
Juntao Kan, Junrui Cheng, Leiming Xu, Molly Hood, Dingfu Zhong

Eur J Nutr· June 2020

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A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis.
Liang Chen, Chun Hu, Molly Hood, Xue Zhang, Lu Zhang

Nutrients· April 2020

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An Integrated Approach Exploring the Synergistic Mechanism of Herbal Pairs in a Botanical Dietary Supplement: A Case Study of a Liver Protection Health Food.
Liang Chen, Chun Hu, Molly Hood, Juntao Kan, Xiaona Gan

Int J Genomics· April 2020

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Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study.
John F Rebhun, Qin Du, Molly Hood, Hailing Guo, Kelly M Glynn

J Tradit Complement Med· July 2019

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Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants.
Bryan D Smith, Michael D Kaufman, Wei-Ping Lu, Anu Gupta, Cynthia B Leary, Molly M Hood

Cancer Cell· May 2019

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The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2 Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.
Allison S Harney, George S Karagiannis, Jeanine Pignatelli, Bryan D Smith, Ece Kadioglu, Molly M Hood

Mol Cancer Ther· November 2017

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A Novel Combination of Wheat Peptides and Fucoidan Attenuates Ethanol-Induced Gastric Mucosal Damage through Anti-Oxidant, Anti-Inflammatory, and Pro-Survival Mechanisms.
Juntao Kan, Molly Hood, Charlie Burns, Jeff Scholten, Jennifer Chuang

Nutrients· September 2017

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Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.
Bryan D Smith, Michael D Kaufman, Cynthia B Leary, Benjamin A Turner, Scott C Wise, Molly M Hood

Mol Cancer Ther· September 2015

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Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells.
James R Henry, Michael D Kaufman, Sheng-Bin Peng, Yu Mi Ahn, Timothy M Caldwell, Molly M Hood

J Med Chem· May 2015

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Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036.
Wayne W Chan, Scott C Wise, Michael D Kaufman, Yu Mi Ahn, Carol L Ensinger, Molly M Hood

Cancer Cell· April 2011

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Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region.
Yu Mi Ahn, Michael Clare, Carol L Ensinger, Molly M Hood, John W Lord

Bioorg Med Chem Lett· October 2010

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The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Lain-Yen Hu, Peter A Boxer, Suzanne R Kesten, Huangshu J Lei, David J Wustrow, Molly Hood

Bioorg Med Chem Lett· May 2006

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