Publications by authors named "MoonSook Lee"

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Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking.
Zhenqiu Huang, Shixiang Sun, Moonsook Lee, Alexander Y Maslov, Miao Shi, Spencer Waldman, Ava Marsh, Taha Siddiqui, Xiao Dong, Yakov Peter

Nat Genet· April 2022

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Single-cell analysis of the somatic mutational landscape in human chondrocytes during aging and in osteoarthritis.
Peijun Ren, Chen Zheng, Yidan Pang, Yu Qiang, Shixiang Sun, Moonsook Lee

Nat Aging· December 2025

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The Somatic Aneuploidy Landscape of Adult Glia Reveals 16p as a Hotspot and Differentiates Mosaicism in Normal Glia from Chromosomal Instability in Glioblastoma.
Cristina Montagna, Olivia Albert, Shixiang Sun, Jhih-Rong Lin, Moonsook Lee

Res Sq· November 2025

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Divergent accumulation patterns of SNVs and INDELs reveal negative selection in noncancerous cells.
Lei Zhang, Moonsook Lee, Xiaoxiao Hao, Xiao Ma, Chuwei Xia

Innovation (Camb)· October 2025

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Effects of aquarobics on back pain, sleep, and memory in older women with chronic pain.
MoonSook Lee, Jiyoun Kim

Medicine (Baltimore)· September 2025

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Uniquely high spontaneous mutational load in blood cells of XP-C patients.
Gordon Fan-Huang, Elizabeth L Schmidt, Moonsook Lee, Shixiang Sun, Christina Boull

bioRxiv· July 2025

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Negative selection allows human primary fibroblasts to tolerate high somatic mutation loads induced by N-ethyl-N-nitrosourea.
Ronald Cutler, Johanna Heid, Shixiang Sun, Moonsook Lee, Alexander Y Maslov

bioRxiv· May 2025

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Blood and Bone-Derived DNA Methylation Ages Predict Mortality After Geriatric Hip Fracture: A Pilot Study.
Sandip P Tarpada, Johanna Heid, Shixiang Sun, Moonsook Lee, Alexander Maslov

J Bone Joint Surg Am· February 2025

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Concurrent analysis of genome and transcriptome in one single cell.
Johanna Heid, Ronald Cutler, Moonsook Lee, Jan Vijg, Alexander Y Maslov

BMC Res Notes· September 2024

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Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts to Tolerate High Levels of Somatic Mutations.
Lei Zhang, Moonsook Lee, Xiaoxiao Hao, Joseph Ehlert, Zhongxuan Chi

bioRxiv· May 2024

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Analyzing somatic mutations by single-cell whole-genome sequencing.
Lei Zhang, Moonsook Lee, Alexander Y Maslov, Cristina Montagna, Jan Vijg

Nat Protoc· February 2024

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Concurrent analysis of genome and transcriptome in one single cell.
Johanna Heid, Ronald Cutler, Moonsook Lee, Jan Vijg, Alexander Y Maslov

Res Sq· August 2023

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Analysis of Somatic Mutations in Senescent Cells Using Single-Cell Whole-Genome Sequencing.
Lei Zhang, Marco De Cecco, Moonsook Lee, Xiaoxiao Hao, Alexander Y Maslov

Aging Biol· June 2023

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Expression of retrotransposons contributes to aging in Drosophila.
Blair K Schneider, Shixiang Sun, Moonsook Lee, Wenge Li, Nicholas Skvir

Genetics· May 2023

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Single-molecule, quantitative detection of low-abundance somatic mutations by high-throughput sequencing.
Alexander Y Maslov, Sergey Makhortov, Shixiang Sun, Johanna Heid, Xiao Dong, Moonsook Lee

Sci Adv· April 2022

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Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers.
Shixiang Sun, Kristina Brazhnik, Moonsook Lee, Alexander Y Maslov, Yi Zhang

J Clin Invest· March 2022

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Maintenance of genome sequence integrity in long- and short-lived rodent species.
Lei Zhang, Xiao Dong, Xiao Tian, Moonsook Lee, Julia Ablaeva, Sang-Goo Lee

Sci Adv· October 2021

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A workflow for simultaneous DNA copy number and methylome analysis of inner cell mass and trophectoderm cells from human blastocysts.
Meir Olcha, Xiao Dong, Heather Feil, Xiaoxiao Hao, Moonsook Lee

Fertil Steril· June 2021

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FOXO3a acts to suppress DNA double-strand break-induced mutations.
Ryan R White, Alexander Y Maslov, Moonsook Lee, Samantha E Wilner, Matthew Levy

Aging Cell· September 2020

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A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses.
Grasiella A Andriani, Elaine Maggi, Daniel Piqué, Samuel E Zimmerman, Moonsook Lee

Sci Rep· July 2019

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Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan.
Lei Zhang, Xiao Dong, Moonsook Lee, Alexander Y Maslov, Tao Wang

Proc Natl Acad Sci U S A· April 2019

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Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung.
Xiao Dong, Miao Shi, Moonsook Lee, Rafael Toro, Silvia Gravina

Epigenetics· February 2019

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Bleomycin-induced genome structural variations in normal, non-tumor cells.
Wilber Quispe-Tintaya, Moonsook Lee, Xiao Dong, Daniel A Weiser, Jan Vijg

Sci Rep· November 2018

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Accurate identification of single-nucleotide variants in whole-genome-amplified single cells.
Xiao Dong, Lei Zhang, Brandon Milholland, Moonsook Lee, Alexander Y Maslov

Nat Methods· May 2017

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Quantitative detection of low-abundance somatic structural variants in normal cells by high-throughput sequencing.
Wilber Quispe-Tintaya, Tatyana Gorbacheva, Moonsook Lee, Sergei Makhortov, Vasily N Popov

Nat Methods· July 2016

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