Publications by authors named "Moran Rubinstein"

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Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy.
JiaJie Teoh, Jane Simko, Chad R Camp, Christine J Liu, Wanqi Wang, Moran Rubinstein

Brain· November 2025

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A mouse model of GRIN2D developmental and epileptic encephalopathy recapitulates the human disease.
Mor Yam, Jolan Nassir, Danielle Galber, Shir Quinn, Roni Gal, Moran Rubinstein

Brain· April 2025

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Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy.
Shir Quinn, Nan Zhang, Timothy A Fenton, Marina Brusel, Preethi Muruganandam, Moran Rubinstein

Biochim Biophys Acta Mol Basis Dis· June 2024

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Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome.
Ana Ricobaraza, Maria Bunuales, Manuela Gonzalez-Aparicio, Saja Fadila, Moran Rubinstein

J Mol Med (Berl)· December 2023

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Viral vector-mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome.
Saja Fadila, Bertrand Beucher, Iria González Dopeso-Reyes, Anat Mavashov, Marina Brusel, Moran Rubinstein

J Clin Invest· June 2023

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Heat-induced seizures, premature mortality, and hyperactivity in a novel nonsense model for Dravet syndrome.
Anat Mavashov, Marina Brusel, Jiaxing Liu, Victoria Woytowicz, Haneui Bae, Moran Rubinstein

Front Cell Neurosci· May 2023

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Acute effect of antiseizure drugs on background oscillations in Dravet syndrome mouse model.
Shir Quinn, Marina Brusel, Mor Ovadia, Moran Rubinstein

Front Pharmacol· March 2023

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Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies.
Gidon Karmon, Shlomo Sragovich, Gal Hacohen-Kleiman, Inbar Ben-Horin-Hazak, Petr Kasparek, Moran Rubinstein

Biol Psychiatry· July 2022

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Functional Investigation of a Neuronal Microcircuit in the CA1 Area of the Hippocampus Reveals Synaptic Dysfunction in Dravet Syndrome Mice.
Yael Almog, Anat Mavashov, Marina Brusel, Moran Rubinstein

Front Mol Neurosci· March 2022

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Transfer of to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations.
Lucia Mora-Jimenez, Miguel Valencia, Rocio Sanchez-Carpintero, Jan Tønnesen, Saja Fadila, Moran Rubinstein

Mol Ther Nucleic Acids· September 2021

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Reprogramming of two induced pluripotent stem cell lines from a heterozygous GRIN2D developmental and epileptic encephalopathy (DEE) patient (BGUi011-A) and from a healthy family relative (BGUi012-A).
Tatiana Rabinski, Sivan T Sagiv, Moran Hausman-Kedem, Aviva Fattal-Valevski, Moran Rubinstein

Stem Cell Res· March 2021

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Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome.
Yael Almog, Saja Fadila, Marina Brusel, Anat Mavashov, Karen Anderson, Moran Rubinstein

Neurobiol Dis· January 2021

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Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1a Dravet syndrome mouse model.
Saja Fadila, Shir Quinn, Ana Turchetti Maia, Daniel Yakubovich, Mor Ovadia, Moran Rubinstein

Epilepsia· October 2020

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Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses.
Prathamesh T Nadar-Ponniah, Shahar Taiber, Michal Caspi, Tal Koffler-Brill, Amiel A Dror, Moran Rubinstein

Front Cell Dev Biol· July 2020

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In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations.
Andreea Nissenkorn, Yael Almog, Inbar Adler, Mary Safrin, Marina Brusel, Moran Rubinstein

PLoS One· November 2019

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Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility.
Boaz Styr, Nir Gonen, Daniel Zarhin, Antonella Ruggiero, Refaela Atsmon, Moran Rubinstein

Neuron· June 2019

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Lithium reduces the span of G protein-activated K (GIRK) channel inhibition in hippocampal neurons.
Nathan Dascal, Moran Rubinstein

Bipolar Disord· November 2017

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A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.
Daniel Yakubovich, Shai Berlin, Uri Kahanovitch, Moran Rubinstein, Isabella Farhy-Tselnicker

PLoS Comput Biol· November 2015

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Dissecting the phenotypes of Dravet syndrome by gene deletion.
Moran Rubinstein, Sung Han, Chao Tai, Ruth E Westenbroek, Avery Hunker

Brain· August 2015

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Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.
Moran Rubinstein, Ruth E Westenbroek, Frank H Yu, Christina J Jones, Todd Scheuer

Neurobiol Dis· January 2015

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Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.
Uri Kahanovitch, Vladimir Tsemakhovich, Shai Berlin, Moran Rubinstein, Boaz Styr

J Physiol· December 2014

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Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures.
Je-Hyun Baek, Moran Rubinstein, Todd Scheuer, James S Trimmer

J Biol Chem· May 2014

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G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK).
Shai Berlin, Tal Keren-Raifman, Ruth Castel, Moran Rubinstein, Carmen W Dessauer

J Biol Chem· February 2010

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Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma.
Moran Rubinstein, Sagit Peleg, Shai Berlin, Dovrat Brass, Tal Keren-Raifman

J Physiol· July 2009

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Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes.
Moran Rubinstein, Sagit Peleg, Shai Berlin, Dovrat Brass, Nathan Dascal

J Physiol· May 2007

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