Publications by authors named "Mu-Fa Zou"

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Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.
Mu-Fa Zou, Jianjing Cao, Ara M Abramyan, Theresa Kopajtic, Claudio Zanettini

J Med Chem· December 2017

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Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs.
Danielle Krout, Akula Bala Pramod, Rejwi Acharya Dahal, Michael J Tomlinson, Babita Sharma, Mu-Fa Zou

Biochem Pharmacol· October 2017

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Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D Receptor (DR) Biased Agonism.
Alessandro Bonifazi, Hideaki Yano, Michael P Ellenberger, Ludovic Muller, Vivek Kumar, Mu-Fa Zou

J Med Chem· April 2017

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Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.
Mu-Fa Zou, Thomas M Keck, Vivek Kumar, Prashant Donthamsetti, Mayako Michino

J Med Chem· April 2016

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Membrane potential shapes regulation of dopamine transporter trafficking at the plasma membrane.
Ben D Richardson, Kaustuv Saha, Danielle Krout, Elizabeth Cabrera, Bruce Felts, Mu-Fa Zou

Nat Commun· January 2016

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2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter.
Takato Hiranita, Derek S Wilkinson, Weimin C Hong, Mu-Fa Zou, Theresa A Kopajtic

J Pharmacol Exp Ther· May 2014

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A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats.
Thomas M Keck, Mu-Fa Zou, Guo-Hua Bi, Hai-Ying Zhang, Xiao-Fei Wang

Addict Biol· March 2014

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Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change.
Gianluigi Tanda, Su Min Li, Maddalena Mereu, Alexandra M Thomas, Aaron L Ebbs, Mu-Fa Zou

Psychopharmacology (Berl)· September 2013

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Metabotropic glutamate receptor 5 negative allosteric modulators as novel tools for in vivo investigation.
Thomas M Keck, Mu-Fa Zou, Peng Zhang, Rebecca P Rutledge, Amy Hauck Newman

ACS Med Chem Lett· July 2012

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Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists.
Anushka B P Fernando, Daina Economidou, David E Theobald, Mu-Fa Zou, Amy H Newman

Psychopharmacology (Berl)· January 2012

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Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells.
Linda Wildling, Christian Rankl, Thomas Haselgrübler, Hermann J Gruber, Marion Holy, Mu-Fa Zou

J Biol Chem· January 2012

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Design and synthesis of substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5.
Mu-Fa Zou, Jianjing Cao, Alice L Rodriguez, P Jeffrey Conn, Amy Hauck Newman

Bioorg Med Chem Lett· May 2011

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Structure-activity relationships in a novel series of 7-substituted-aryl quinolines and 5-substituted-aryl benzothiazoles at the metabotropic glutamate receptor subtype 5.
Peng Zhang, Mu-Fa Zou, Alice L Rodriguez, P Jeffrey Conn, Amy Hauck Newman

Bioorg Med Chem· May 2010

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Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.
Santosh S Kulkarni, Mu-Fa Zou, Jianjing Cao, Jeffrey R Deschamps, Alice L Rodriguez

J Med Chem· June 2009

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Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs.
Jacob Eriksen, Søren G F Rasmussen, Trine Nygaard Rasmussen, Christian Bjerggaard Vaegter, Joo Hwan Cha, Mu-Fa Zou

J Neurosci· May 2009

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Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites.
M Laura Parnas, Jon D Gaffaney, Mu Fa Zou, John R Lever, Amy Hauck Newman

Mol Pharmacol· April 2008

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Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.
Claus J Loland, Rajeev I Desai, Mu-Fa Zou, Jianjing Cao, Peter Grundt

Mol Pharmacol· March 2008

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Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.
Mu-Fa Zou, Jianjing Cao, Theresa Kopajtic, Rajeev I Desai, Jonathan L Katz

J Med Chem· October 2006

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Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
L Keith Henry, Julie R Field, Erika M Adkins, M Laura Parnas, Roxanne A Vaughan, Mu-Fa Zou

J Biol Chem· January 2006

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Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter.
Joo Hwan Cha, Mu-Fa Zou, Erika M Adkins, Søren G F Rasmussen, Claus Juul Loland

J Med Chem· December 2005

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Radioiodinated azide and isothiocyanate derivatives of cocaine for irreversible labeling of dopamine transporters: synthesis and covalent binding studies.
John R Lever, Mu-Fa Zou, M Laura Parnas, Romain A Duval, Sara E Wirtz

Bioconjug Chem· September 2005

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Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.
Mu-Fa Zou, Theresa Kopajtic, Jonathan L Katz, Amy Hauck Newman

J Med Chem· July 2003

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Enantioselective synthesis of S-(+)-2beta-carboalkoxy-3alpha-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter.
Mu-Fa Zou, Gregory E Agoston, Yuri Belov, Theresa Kopajtic, Jonathan L Katz

Bioorg Med Chem Lett· May 2002

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Synthesis of (E)-Alkenyl Iodides via (E)-[2'-(Tributyltin)alkenyl]dialkylboranes with Iodine.
Mu-Fa Zou, Min-Zhi Deng

J Org Chem· March 1996

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