Publications by authors named "Nancy Loos"

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Supporting the Well-Being of Nurses: Best Practices Used by California Nurse Leaders.
Evangeline Fangonil-Gagalang, Hannah Jang Kim, Fang-Yu Chou, Kim Failla, Veronica S Timple, Nancy Loos

Nurs Adm Q· December 2025

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Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.
Jamie Rijmers, Rolf W Sparidans, Manon Acda, Nancy H C Loos, Emmanouela Epeslidou

Mol Pharm· October 2024

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Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.
Nancy H C Loos, Viët Bui, Daniëlle H de Jong, Maria C Lebre, Hilde Rosing

Cancer Chemother Pharmacol· July 2024

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Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice.
Nancy H C Loos, Margarida L Ferreira Martins, Jamie Rijmers, Daniëlle de Jong, Maria C Lebre

Mol Pharm· April 2024

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The ABCB1 and ABCG2 efflux transporters limit brain disposition of the SYK inhibitors entospletinib and lanraplenib.
Nancy H C Loos, Rolf W Sparidans, Paniz Heydari, Viët Bui, Maria C Lebre

Toxicol Appl Pharmacol· April 2024

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Coadministration of ABCB1/P-glycoprotein inhibitor elacridar improves tissue distribution of ritonavir-boosted oral cabazitaxel in mice.
Nancy H C Loos, Margarida L F Martins, Daniëlle de Jong, Maria C Lebre, Matthijs Tibben

Int J Pharm· January 2024

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Development and validation of an HPLC-MS/MS method to quantify the KRAS inhibitor adagrasib in mouse plasma and tissue-related matrices.
Irene A Retmana, Nancy H C Loos, Alfred H Schinkel, Jos H Beijnen, Rolf W Sparidans

Biomed Chromatogr· November 2023

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Validated LC-MS/MS method for simultaneous quantification of KRAS inhibitor sotorasib and its major circulating metabolite (M24) in mouse matrices and its application in a mouse pharmacokinetic study.
Irene A Retmana, Nancy H C Loos, Alfred H Schinkel, Jos H Beijnen, Rolf W Sparidans

J Pharm Biomed Anal· October 2023

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Pharmacokinetics of the KRAS inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c.
Nancy H C Loos, Irene A Retmana, Jamie Rijmers, Yaogeng Wang, Changpei Gan

Biomed Pharmacother· October 2023

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P-glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Main Active Heroin Metabolites 6-monoacetylmorphine (6-MAM) and Morphine in Mice.
Margarida L F Martins, Nancy H C Loos, Malika El Yattouti, Lianda Offeringa, Paniz Heydari

Pharm Res· August 2023

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The inhibitory and inducing effects of ritonavir on hepatic and intestinal CYP3A and other drug-handling proteins.
Nancy H C Loos, Jos H Beijnen, Alfred H Schinkel

Biomed Pharmacother· June 2023

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Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.
Nancy H C Loos, Margarida L F Martins, Daniëlle de Jong, Maria C Lebre, Matthijs Tibben

Mol Pharm· May 2023

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Equipping Nurses to Lead Evidence-Based Practice: An Opportunity for Professional Nursing Associations.
Lee Galuska, Nancy Loos, Lina Najib Kawar, Bindu Thomas, Lynn Gallagher-Ford

J Nurs Adm· October 2022

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The Mechanism-Based Inactivation of CYP3A4 by Ritonavir: What Mechanism?
Nancy H C Loos, Jos H Beijnen, Alfred H Schinkel

Int J Mol Sci· August 2022

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ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.
Alejandra Martínez-Chávez, Nancy H C Loos, Maria C Lebre, Matthijs M Tibben, Hilde Rosing

Pharmacol Res· April 2022

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ABCB1 limits brain exposure of the KRAS inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.
Nancy H C Loos, Irene A Retmana, Wenlong Li, Margarida L F Martins, Maria C Lebre

Pharmacol Res· April 2022

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P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib.
Margarida L F Martins, Nancy H C Loos, Sümeyra Mucuk, Danielle de Jong, Maria C Lebre

Mol Pharm· December 2021

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Quantification of KRAS inhibitor sotorasib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.
Irene A Retmana, Nancy H C Loos, Alfred H Schinkel, Jos H Beijnen, Rolf W Sparidans

J Chromatogr B Analyt Technol Biomed Life Sci· June 2021

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Nurse Listening as Perceived by Patients: How to Improve the Patient Experience, Keep Patients Safe, and Raise HCAHPS Scores.
Nancy Mestler Loos

J Nurs Adm· June 2021

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