Publications by authors named "Nathan Treff"

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Accuracy of Direct Mutation Testing by TaqMan qPCR for Preimplantation Genetic Diagnosis of Recurrent de Novo Mutations.
Diana Garro, Jia Xu, Deirdre Leahy, Jennifer Eccles, Nathan R Treff

Fertil Steril· December 2025

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Blastocyst segmental aneuploidy breakpoints are highly correlated with human genome fragile sites.
Elaine de Quadros, Jia Xu, Nathan Treff, Diego Marin, Arielle Freedman

Hum Reprod· October 2025

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Routine detection of consanguinity through preimplantation genetic testing in human embryos.
Catherine Kratka, Jia Xu, Jennifer Eccles, Diego Marin, Nathan Treff

Reprod Biomed Online· May 2025

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Correspondence on "Clinical utility of polygenic risk scores for embryo selection: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)" by Grebe et al.
Erik Widen, Louis Lello, Jennifer Eccles, Diego Marin, Nathan R Treff

Genet Med· August 2024

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The severity of meiotic aneuploidy is associated with altered morphokinetic variables of mouse oocyte maturation.
Yiru Zhu, Catherine R Kratka, Jeffrey Pea, Hoi Chang Lee, Caroline E Kratka, Nathan R Treff

Hum Reprod Open· April 2024

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High-resolution PGT-A results in incidental identification of patients with small pathogenic copy number variants.
Deirdre Leahy, Diego Marin, Jia Xu, Jennifer Eccles, Nathan R Treff

J Assist Reprod Genet· January 2024

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Accurate detection and frequency of abnormal ploidy in the human blastocyst.
Catherine Kratka, Padma Samhita Vadapalli, Robert Mendola, John Garrisi, Jia Xu, Nathan R Treff

F S Sci· May 2023

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Genetics of the preimplantation embryo.
Nathan R Treff

F S Sci· May 2023

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Identifying parental and cell-division origins of aneuploidy in the human blastocyst.
Bhavini Rana, Kevin Lambrese, Robert Mendola, Jia Xu, John Garrisi, Nathan R Treff

Am J Hum Genet· April 2023

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Scientific refutation of ESHG statement on embryo selection.
Laurent Christian Asker Melchior Tellier, Nathan Robert Treff, Stephen Dao Hui Hsu, Louis Lello, Erik Widen

Eur J Hum Genet· March 2023

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On the reproductive capabilities of aneuploid human preimplantation embryos.
Antonio Capalbo, Maurizio Poli, Chaim Jalas, Eric J Forman, Nathan R Treff

Am J Hum Genet· September 2022

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Should preimplantation genetic testing for polygenic disease be offered to all - or none?
Nathan R Treff, Julian Savulescu, Inmaculada de Melo-Martín, Lee P Shulman, Eve C Feinberg

Fertil Steril· June 2022

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Editorial: Causes of Oocyte Aneuploidy and Infertility in Advanced Maternal Age and Emerging Therapeutic Approaches.
Lori R Bernstein, Nathan R Treff

Front Endocrinol (Lausanne)· December 2021

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The "mosaic" embryo: misconceptions and misinterpretations in preimplantation genetic testing for aneuploidy.
Nathan R Treff, Diego Marin

Fertil Steril· November 2021

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Use of Polygenic Scores to Select Embryos.
Nathan R Treff, Laurent C A M Tellier, Stephen D H Hsu

N Engl J Med· October 2021

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A novel test for annexin A5 M2 haplotyping in in vitro fertilization patients and preimplantation embryos.
Bhavini Rana, Raymond Zimmerman, Diego Marin, Jia Xu, Edward Messick, Nathan Treff

F S Sci· August 2021

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Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations.
Laurent C A M Tellier, Jennifer Eccles, Nathan R Treff, Louis Lello, Simon Fishel

Genes (Basel)· July 2021

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Preimplantation genetic testing for aneuploidy: A review of published blastocyst reanalysis concordance data.
Diego Marin, Jia Xu, Nathan R Treff

Prenat Diagn· April 2021

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Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos.
Michael V Zuccaro, Jia Xu, Carl Mitchell, Diego Marin, Raymond Zimmerman, Nathan Treff

Cell· December 2020

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Isn't it time to stop calling preimplantation embryos "mosaic"?
Richard J Paulson, Nathan R Treff

F S Rep· December 2020

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PREIMPLANTATION GENETIC TESTING: Preimplantation genetic testing for polygenic disease risk.
Nathan R Treff, Diego Marin, Louis Lello, Stephen Hsu, Laurent C A M Tellier

Reproduction· November 2020

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Exome sequencing links CEP120 mutation to maternally derived aneuploid conception risk.
Katarzyna M Tyc, Warif El Yakoubi, Aishee Bag, Jessica Landis, Yiping Zhan, Nathan R Treff

Hum Reprod· September 2020

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Polygenic risk scoring in the human embryo: reproductive genetics, final frontier?
Nathan R Treff

F S Sci· August 2020

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Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs.
Nathan R Treff, Jennifer Eccles, Diego Marin, Edward Messick, Louis Lello

Genes (Basel)· June 2020

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Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction.
Nathan R Treff, Jennifer Eccles, Lou Lello, Elan Bechor, Jeffrey Hsu

Front Endocrinol (Lausanne)· December 2019

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