Publications by authors named "Nathan Zammit"

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Regulatory T cells in brown adipose tissue safeguard thermogenesis by restraining interferon-γ-producing lymphocytes.
Nathan W Zammit, Ariana Vargas-Castillo, P Kent Langston, Gang Wang, Yangzhong Zhou

Sci Immunol· July 2025

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Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle.
Ariana Vargas-Castillo, Yizhi Sun, Amanda L Smythers, Louisa Grauvogel, Phillip A Dumesic, Nathan W Zammit

Cell Metab· September 2024

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RELA governs a network of islet-specific metabolic genes necessary for beta cell function.
Nathan W Zammit, Ying Ying Wong, Stacey N Walters, Joanna Warren, Simon C Barry

Diabetologia· August 2023

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The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury.
Natasha M Rogers, Nathan Zammit, Danny Nguyen-Ngo, Yassine Souilmi, Nikita Minhas

Kidney Int· June 2023

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The retroelement Lx9 puts a brake on the immune response to virus infection.
Nenad Bartonicek, Romain Rouet, Joanna Warren, Claudia Loetsch, Gabriela Santos Rodriguez, Nathan Zammit

Nature· August 2022

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TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation.
Nathan W Zammit, Joseph McDowell, Joanna Warren, Walter Muskovic, Joanne Gamble

Front Immunol· April 2022

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Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation.
Nathan W Zammit, Karen L Seeberger, Jad Zamerli, Stacey N Walters, Leszek Lisowski

Xenotransplantation· May 2021

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A zebrafish functional genomics model to investigate the role of human A20 variants in vivo.
Daniele Cultrone, Nathan W Zammit, Eleanor Self, Benno Postert, Jeremy Z R Han

Sci Rep· November 2020

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Spatial and Temporal Control of CRISPR-Cas9-Mediated Gene Editing Delivered via a Light-Triggered Liposome System.
Yagiz Alp Aksoy, Biyao Yang, Wenjie Chen, Tzongtyng Hung, Rhiannon P Kuchel, Nathan W Zammit

ACS Appl Mater Interfaces· November 2020

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A20 as an immune tolerance factor can determine islet transplant outcomes.
Nathan W Zammit, Stacey N Walters, Karen L Seeberger, Philip J O'Connell, Gregory S Korbutt

JCI Insight· November 2019

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Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Nathan W Zammit, Owen M Siggs, Paul E Gray, Keisuke Horikawa, David B Langley

Nat Immunol· October 2019

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β Cell Replacement Therapy: The Next 10 Years.
Christian Schuetz, Takayuki Anazawa, Sarah E Cross, Leticia Labriola, Raphael P H Meier, Nathan W Zammit

Transplantation· February 2018

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Equipping the islet graft for self defence: targeting nuclear factor κB and implications for tolerance.
Nathan W Zammit, Shane T Grey

Curr Opin Organ Transplant· February 2018

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Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice.
Jeanette E Villanueva, Stacey N Walters, Mitsuru Saito, Elisabeth K Malle, Nathan W Zammit

Diabetologia· April 2017

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MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD.
Alan C-Y Hsu, Kamal Dua, Malcolm R Starkey, Tatt-Jhong Haw, Prema M Nair, Nathan Zammit

JCI Insight· April 2017

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Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.
Elisabeth K Malle, Nathan W Zammit, Stacey N Walters, Yen Chin Koay, Jianmin Wu

J Exp Med· July 2015

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TRAF2 regulates peripheral CD8(+) T-cell and NKT-cell homeostasis by modulating sensitivity to IL-15.
Jeanette E Villanueva, Elisabeth K Malle, Sandra Gardam, Pablo A Silveira, Nathan W Zammit

Eur J Immunol· June 2015

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Emerging roles for A20 in islet biology and pathology.
Nathan W Zammit, Shane T Grey

Adv Exp Med Biol· October 2014

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Low-dose rapamycin unmasks the protective potential of targeting intragraft NF-κB for islet transplants.
Nathan W Zammit, Bernice M Tan, Stacey N Walters, David Liuwantara, Jeanette E Villanueva

Cell Transplant· August 2014

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Human islets express a marked proinflammatory molecular signature prior to transplantation.
Mark J Cowley, Anita Weinberg, Nathan W Zammit, Stacey N Walters, Wayne J Hawthorne

Cell Transplant· December 2013

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Acute phase proteins are major clients for the chaperone action of α₂-macroglobulin in human plasma.
Amy R Wyatt, Nathan W Zammit, Mark R Wilson

Cell Stress Chaperones· March 2013

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