Publications by authors named "Natsuki Shikida"

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Biological Evaluation of Cleavable Linkers in Exatecan-Based Antibody-Drug Conjugates: A Comparative Study of DXd and Exo-Linker Platforms.
Tomohiro Watanabe, Yusuke Iwai, Natsuki Shikida, Jason T Stofleth, Tomohiro Fujii

ACS Omega· September 2025

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Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates.
Tomohiro Watanabe, Naoko Arashida, Tomohiro Fujii, Natsuki Shikida, Kenichiro Ito

J Med Chem· October 2024

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AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Selective Antibody-Drug Conjugate Synthesis.
Yutaka Matsuda, Natsuki Shikida, Noriko Hatada, Kei Yamada, Takuya Seki

Org Lett· July 2024

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Analytical studies on the conjugation site specificity of trastuzumab modified by Escherichia coli lipoate ligase A: multiple-enzyme digestion approach for peptide mapping.
Natsuki Shikida, Shunsuke Yamazaki, Kazutoshi Takahashi, Yutaka Matsuda, Kazutaka Shimbo

Anal Bioanal Chem· November 2023

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AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production.
Tomohiro Fujii, Yutaka Matsuda, Takuya Seki, Natsuki Shikida, Yusuke Iwai

Bioconjug Chem· March 2023

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Single-chain tandem macrocyclic peptides as a scaffold for growth factor and cytokine mimetics.
Kenichiro Ito, Yoshihiko Matsuda, Ayako Mine, Natsuki Shikida, Kazutoshi Takahashi

Commun Biol· January 2022

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Lipoate-acid ligase a modification of native antibody: Synthesis and conjugation site analysis.
Shunsuke Yamazaki, Natsuki Shikida, Kazutoshi Takahashi, Yutaka Matsuda, Kota Inoue

Bioorg Med Chem Lett· November 2021

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AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies.
Kei Yamada, Natsuki Shikida, Kazutaka Shimbo, Yuji Ito, Zahra Khedri

Angew Chem Int Ed Engl· April 2019

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