Publications by authors named "Takuya Seki"

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Biological Evaluation of Cleavable Linkers in Exatecan-Based Antibody-Drug Conjugates: A Comparative Study of DXd and Exo-Linker Platforms.
Tomohiro Watanabe, Yusuke Iwai, Natsuki Shikida, Jason T Stofleth, Tomohiro Fujii, Takuya Seki

ACS Omega· September 2025

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Homogeneous Dual-Payload Antibody-Drug Conjugates Produced by Combined Distinct Conjugation Strategies.
Tomohiro Watanabe, Yusuke Iwai, Jason T Stofleth, Tomohiro Fujii, Takuya Seki

ACS Med Chem Lett· July 2025

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Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates.
Tomohiro Watanabe, Naoko Arashida, Tomohiro Fujii, Natsuki Shikida, Kenichiro Ito, Takuya Seki

J Med Chem· October 2024

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AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Selective Antibody-Drug Conjugate Synthesis.
Yutaka Matsuda, Natsuki Shikida, Noriko Hatada, Kei Yamada, Takuya Seki

Org Lett· July 2024

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Spectral Tuning and Excitation-Energy Transfer by Unique Carotenoids in Diatom Light-Harvesting Antenna.
Kazuhiro J Fujimoto, Takuya Seki, Takumi Minoda, Takeshi Yanai

J Am Chem Soc· February 2024

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Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second-Generation.
Tomohiro Fujii, Kenichiro Ito, Kazutoshi Takahashi, Tsubasa Aoki, Rika Takasugi, Takuya Seki

ACS Med Chem Lett· December 2023

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Report on 2021 International workshop for non-animal approaches in the food sector (Japan): Current status and avenues for further research.
Satoshi Ohta, Shigeki Kimura, Daisuke Maejima, Kazutoshi Saito, Yasuhiro Tanaka, Takuya Seki

ALTEX· April 2023

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AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production.
Tomohiro Fujii, Yutaka Matsuda, Takuya Seki, Natsuki Shikida, Yusuke Iwai

Bioconjug Chem· March 2023

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Biological Evaluation of Maytansinoid-Based Site-Specific Antibody-Drug Conjugate Produced by Fully Chemical Conjugation Approach: AJICAP®.
Takuya Seki, Kei Yamada, Yuri Ooba, Tomohiro Fujii, Takahiro Narita

Front Biosci (Landmark Ed)· August 2022

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Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates.
Yutaka Matsuda, Takuya Seki, Kei Yamada, Yuri Ooba, Kazutoshi Takahashi

Mol Pharm· November 2021

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Genotoxicity and repeated-dose toxicity evaluation of dried Mankai.
Yasuko Kawamata, Yusuke Shibui, Asuka Takumi, Takuya Seki, Tomoko Shimada

Toxicol Rep· September 2020

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Evaluation of a Novel Boron-Containing α-D-Mannopyranoside for BNCT.
Takao Tsurubuchi, Makoto Shirakawa, Wataru Kurosawa, Kayo Matsumoto, Risa Ubagai, Takuya Seki

Cells· May 2020

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