Publications by authors named "Neal D Tolley"

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Heme and hemozoin induce platelet cell death through UPR-induced apoptosis and ferroptosis in vivax malaria.
Milena Tavares Gomes, Isabel Matos Medeiros-de-Moraes, Adriana Vieira-de-Abreu, Isaclaudia G Azevedo-Quintanilha, Thayane Modesto Fontes, Neal D Tolley

Blood Adv· October 2025

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Plasma Preparation Strategies for Extracellular Vesicle-Based Biomarkers in Metastatic Castration-Resistant Prostate Cancer.
Prima Dewi Sinawang, Priyanka Multani, Mehmet O Ozen, Jodie Wong, Demir Akin, Neal D Tolley

J Extracell Biol· August 2025

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Heterozygous Eif4nif1 Stop-Gain Mice Replicate the Primary Ovarian Insufficiency Phenotype in Women.
Mika Moriwaki, Lihua Liu, Emma R James, Neal D Tolley, Ashley M O'Connor

Endocrinology· February 2025

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Prospective, international, multisite comparison of platelet isolation techniques for genome-wide transcriptomics: communication from the SSC of the ISTH.
Meenakshi Banerjee, Jesse W Rowley, Chris J Stubben, Neal D Tolley, Kathleen Freson

J Thromb Haemost· October 2024

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Aging-related alterations in mechanistic target of rapamycin signaling promote platelet hyperreactivity and thrombosis.
Irina Portier, Bhanu Kanth Manne, Yasuhiro Kosaka, Neal D Tolley, Frederik Denorme

J Thromb Haemost· September 2024

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Mitofusin-2 Regulates Platelet Mitochondria and Function.
Shancy Jacob, Yasuhiro Kosaka, Seema Bhatlekar, Frederik Denorme, Haley Benzon, Neal D Tolley

Circ Res· January 2024

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The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes.
Frederik Denorme, Nicole D Armstrong, Michelle L Stoller, Irina Portier, Emilia A Tugolukova, Neal D Tolley

J Clin Invest· September 2023

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Prospective, randomized, controlled, trial to assess ASA DOSing by body mass index in HEalthy volunteers (DOSE study).
Isaac Nay, Doug Hutchinson, Matthew Rondina, Kibum Kim, Rachel Kroencke, Neal D Tolley

Pharmacotherapy· March 2023

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MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis.
Bhanu Kanth Manne, Robert A Campbell, Seema Bhatlekar, Abigail Ajanel, Frederik Denorme, Neal D Tolley

Blood· December 2022

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IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis.
Robert A Campbell, Bhanu Kanth Manne, Meenakshi Banerjee, Elizabeth A Middleton, Abigail Ajanel, Neal D Tolley

J Clin Invest· December 2022

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Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5.
Hansjörg Schwertz, Jesse W Rowley, Irina Portier, Elizabeth A Middleton, Neal D Tolley

Autophagy· July 2022

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Platelet MHC class I mediates CD8+ T-cell suppression during sepsis.
Li Guo, Sikui Shen, Jesse W Rowley, Neal D Tolley, Wenwen Jia

Blood· August 2021

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Heparanase expression and activity are increased in platelets during clinical sepsis.
Alicia S Eustes, Robert A Campbell, Elizabeth A Middleton, Neal D Tolley, Bhanu K Manne

J Thromb Haemost· May 2021

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CRISPR-edited megakaryocytes for rapid screening of platelet gene functions.
Emilie Montenont, Seema Bhatlekar, Shancy Jacob, Yasuhiro Kosaka, Bhanu K Manne, Neal D Tolley

Blood Adv· May 2021

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Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading.
Callie Frey, Antigoni G Koliopoulou, Emilie Montenont, Neal D Tolley, Hadi Javan

Platelets· October 2020

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Platelet gene expression and function in patients with COVID-19.
Bhanu Kanth Manne, Frederik Denorme, Elizabeth A Middleton, Irina Portier, Jesse W Rowley, Neal D Tolley

Blood· September 2020

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Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet Splice QTL.
Matthew T Rondina, Deepak Voora, Lukas M Simon, Hansjörg Schwertz, Julie F Harper, Neal D Tolley

Circ Res· February 2020

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Sepsis alters the transcriptional and translational landscape of human and murine platelets.
Elizabeth A Middleton, Jesse W Rowley, Robert A Campbell, Colin K Grissom, Samuel M Brown, Neal D Tolley

Blood· September 2019

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Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3.
Robert A Campbell, Hansjorg Schwertz, Eugenio D Hottz, Jesse W Rowley, Bhanu Kanth Manne, Neal D Tolley

Blood· May 2019

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Vms1p is a release factor for the ribosome-associated quality control complex.
Olga Zurita Rendón, Eric K Fredrickson, Conor J Howard, Jonathan Van Vranken, Sarah Fogarty, Neal D Tolley

Nat Commun· June 2018

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Assessing protein synthesis by platelets.
Hansjörg Schwertz, Jesse W Rowley, Neal D Tolley, Robert A Campbell, Andrew S Weyrich

Methods Mol Biol· April 2012

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Novel anti-bacterial activities of β-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation.
Bjoern F Kraemer, Robert A Campbell, Hansjörg Schwertz, Mark J Cody, Zechariah Franks, Neal D Tolley

PLoS Pathog· November 2011

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Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes.
Jesse W Rowley, Andrew J Oler, Neal D Tolley, Benjamin N Hunter, Elizabeth N Low

Blood· October 2011

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Megakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events.
Luca Cecchetti, Neal D Tolley, Noemi Michetti, Loredana Bury, Andrew S Weyrich

Blood· August 2011

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Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.
Roland Schmidt, Andreas Bültmann, Sina Fischel, Angelika Gillitzer, Paul Cullen, Neal D Tolley

Circ Res· February 2008

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