Publications by authors named "Shancy Jacob"

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Functional classification of platelet gene variants using CRISPR HDR in CD34 cell-derived megakaryocytes.
Yasuhiro Kosaka, Brandon Lopez, Nina Kishimoto, Shancy Jacob, Emilie Montenont

Am J Hum Genet· December 2025

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Actin-bundling protein L-plastin promotes megakaryocyte rigidity and dampens proplatelet formation.
Li Guo, Shancy Jacob, Bhanu Kanth Manne, E Motunrayo Kolawole, Siqi Guo

Haematologica· January 2024

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Mitofusin-2 Regulates Platelet Mitochondria and Function.
Shancy Jacob, Yasuhiro Kosaka, Seema Bhatlekar, Frederik Denorme, Haley Benzon

Circ Res· January 2024

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The fate of mitochondria during platelet activation.
Alexei Grichine, Shancy Jacob, Anita Eckly, Joran Villaret, Clotilde Joubert

Blood Adv· October 2023

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MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis.
Bhanu Kanth Manne, Robert A Campbell, Seema Bhatlekar, Abigail Ajanel, Frederik Denorme, Shancy Jacob

Blood· December 2022

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Interferon α-induced SAMHD1 regulates human cultured megakaryocyte apoptosis and proplatelet formation.
Seema Bhatlekar, Shancy Jacob, Emilia Tugolukova, Bhanu K Manne, Yasuhiro Kosaka

Haematologica· February 2022

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Megakaryocyte-specific knockout of the Mir-99b/let7e/125a cluster lowers platelet count without altering platelet function.
Seema Bhatlekar, Shancy Jacob, Bhanu K Manne, Li Guo, Frederik Denorme

Blood Cells Mol Dis· December 2021

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Platelet MHC class I mediates CD8+ T-cell suppression during sepsis.
Li Guo, Sikui Shen, Jesse W Rowley, Neal D Tolley, Wenwen Jia, Shancy P Jacob

Blood· August 2021

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Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils.
Mosale Seetharam Sumanth, Shancy P Jacob, Kandahalli Venkataranganayaka Abhilasha, Bhanu Kanth Manne, Venkatesha Basrur

J Leukoc Biol· May 2021

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CRISPR-edited megakaryocytes for rapid screening of platelet gene functions.
Emilie Montenont, Seema Bhatlekar, Shancy Jacob, Yasuhiro Kosaka, Bhanu K Manne

Blood Adv· May 2021

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p38 MAP-kinase inhibitor protects against platelet-activating factor-induced death in mice.
Kandahalli Venkataranganayaka Abhilasha, Mosale Seetharam Sumanth, Vyala Hanumanthareddy Chaithra, Shancy Petsel Jacob, Anita Thyagarajan

Free Radic Biol Med· November 2019

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Acute phase protein, α - 1- acid glycoprotein (AGP-1), has differential effects on TLR-2 and TLR-4 mediated responses.
Mosale Seetharam Sumanth, Kandahalli Venkataranganayaka Abhilasha, Shancy Petsel Jacob, Vyala Hanumanthareddy Chaithra, Venkatesha Basrur

Immunobiology· September 2019

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Modulation of inflammatory platelet-activating factor (PAF) receptor by the acyl analogue of PAF.
Vyala Hanumanthareddy Chaithra, Shancy Petsel Jacob, Chikkamenahalli Lakshminarayana Lakshmikanth, Mosale Seetharam Sumanth, Kandahalli Venkataranganayaka Abhilasha

J Lipid Res· November 2018

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Escherichia coli Braun Lipoprotein (BLP) exhibits endotoxemia - like pathology in Swiss albino mice.
Chikkamenahalli Lakshminarayana Lakshmikanth, Shancy Petsel Jacob, Avinash Kundadka Kudva, Calivarathan Latchoumycandane, Puttaraju Srikanta Murthy Yashaswini

Sci Rep· October 2016

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Sepsis: in search of cure.
Chikkamenahalli Lakshminarayana Lakshmikanth, Shancy Petsel Jacob, Vyala Hanumanthareddy Chaithra, Hugo Caire de Castro-Faria-Neto, Gopal Kedihithlu Marathe

Inflamm Res· August 2016

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Lipopolysaccharide Cross-Tolerance Delays Platelet-Activating Factor-Induced Sudden Death in Swiss Albino Mice: Involvement of Cyclooxygenase in Cross-Tolerance.
Shancy Petsel Jacob, Chikkamenahalli Lakshminarayana Lakshmikanth, Vyala Hanumanthareddy Chaithra, Titus Ruth Shantha Kumari, Chu-Huang Chen

PLoS One· August 2016

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To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase.
Gopal Kedihitlu Marathe, Chaitanya Pandit, Chikkamenahalli Lakshminarayana Lakshmikanth, Vyala Hanumanthareddy Chaithra, Shancy Petsel Jacob

J Lipid Res· September 2014

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