Publications by authors named "Neal Simon"

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The utility of the irritability scale in Huntington's disease patients with evidence of irritability or aggression.
Joyce En-Hua Wang, Neal G Simon, Michael J Brownstein, Hilda T Maibach, Jacob Maibach

Parkinsonism Relat Disord· June 2024

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A proof-of-concept randomized crossover clinical trial of a first-in-class vasopressin 1a receptor antagonist for PTSD: Design, methods, and recruitment.
JoAnn Difede, Andrew A McAleavey, Mariel Emrich, Adina Jick, Annell Ovalles, Neal G Simon

Contemp Clin Trials Commun· June 2023

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The Vasopressin 1a Receptor Antagonist SRX246 Reduces Aggressive Behavior in Huntington's Disease.
Hilda T Maibach, Michael J Brownstein, Steven M Hersch, Karen E Anderson, Debra E Itzkowitz, Neal G Simon

J Pers Med· September 2022

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The novel vasopressin receptor (V1aR) antagonist SRX246 reduces anxiety in an experimental model in humans: a randomized proof-of-concept study.
Tiffany R Lago, Michael J Brownstein, Emily Page, Emily Beydler, Adrienne Manbeck, Neal Simon

Psychopharmacology (Berl)· September 2021

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Evidence of early vasogenic edema following minor head impact that can be reduced with a vasopressin V1a receptor antagonist.
Praveen Kulkarni, Mansi R Bhosle, Shi-Fang Lu, Neal S Simon, Sade Iriah

Brain Res Bull· December 2020

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Safety and Tolerability of SRX246, a Vasopressin 1a Antagonist, in Irritable Huntington's Disease Patients-A Randomized Phase 2 Clinical Trial.
Michael J Brownstein, Neal G Simon, Jeffrey D Long, Jon Yankey, Hilda T Maibach

J Clin Med· November 2020

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Treating head injury using a novel vasopressin 1a receptor antagonist.
Thomas R Morrison, Praveen Kulkarni, Xuezhu Cai, Sade Iriah, Dipak Aggarwal, Neal G Simon

Neurosci Lett· January 2020

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Neuroradiological Changes Following Single or Repetitive Mild TBI.
Praveen Kulkarni, Thomas R Morrison, Xuezhu Cai, Sade Iriah, Neal Simon

Front Syst Neurosci· August 2019

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Challenges in developing drugs for neurological and psychiatric disorders.
Neal G Simon, Michael J Brownstein

Prog Neurobiol· May 2017

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A novel V1a receptor antagonist blocks vasopressin-induced changes in the CNS response to emotional stimuli: an fMRI study.
Royce J Lee, Emil F Coccaro, Henk Cremers, Rosemary McCarron, Shi-Fang Lu, Neal G Simon

Front Syst Neurosci· December 2013

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Pharmacokinetics and metabolism of SRX246: a potent and selective vasopressin 1a antagonist.
Karine M Fabio, Christophe D Guillon, Shi-Fang Lu, Ned D Heindel, Michael J Brownstein, Neal G Simon

J Pharm Sci· June 2013

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Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging.
Karine Fabio, Christophe Guillon, Carl J Lacey, Shi-fang Lu, Ned D Heindel, Neal G Simon

Bioorg Med Chem· February 2012

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Peromyscus maniculatus, a possible reservoir host of Borrelia garinii from the Gannet Islands off Newfoundland and Labrador.
Eric M Baggs, Stephanie H Stack, Jean R Finney-Crawley, Neal P P Simon

J Parasitol· October 2011

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Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus.
Qianxing Mo, Shifang Lu, Carrie Garippa, Michael J Brownstein, Neal G Simon

J Steroid Biochem Mol Biol· April 2009

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Imaging the neural circuitry and chemical control of aggressive motivation.
Craig F Ferris, Tara Stolberg, Praveen Kulkarni, Murali Murugavel, Robert Blanchard, Neal G Simon

BMC Neurosci· November 2008

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Vasopressin antagonists as anxiolytics and antidepressants: recent developments.
Neal G Simon, Christophe Guillon, Karine Fabio, Ned D Heindel, Shi-fang Lu

Recent Pat CNS Drug Discov· June 2008

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Azetidinones as vasopressin V1a antagonists.
Christophe D Guillon, Gary A Koppel, Michael J Brownstein, Michael O Chaney, Craig F Ferris, Neal G Simon

Bioorg Med Chem· March 2007

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Hormonal pathways regulating intermale and interfemale aggression.
Neal G Simon, Qianxing Mo, Shan Hu, Carrie Garippa, Shi-Fang Lu

Int Rev Neurobiol· August 2006

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Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity.
Qianxing Mo, Shi-fang Lu, Neal G Simon

J Steroid Biochem Mol Biol· April 2006

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Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior.
Craig F Ferris, Shi-Fang Lu, Tara Messenger, Christophe D Guillon, Ned Heindel, Neal G Simon

Pharmacol Biochem Behav· February 2006

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ERbeta protein expression in female cynomolgus monkey and CF-1 mouse brain: Western analysis.
Shan Hu, Shi-Fang Lu, Jay R Kaplan, Michael R Adams, Neal G Simon

J Neurobiol· September 2005

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Neurodevelopmental outcome and growth at 18 to 22 months' corrected age in extremely low birth weight infants treated with early erythropoietin and iron.
Robin K Ohls, Richard A Ehrenkranz, Abhik Das, Anna M Dusick, Kimberly Yolton, Neal P Simon

Pediatrics· November 2004

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Changes in newborn bathing practices may increase the risk for omphalitis.
Neal P Simon, Michael W Simon

Clin Pediatr (Phila)· October 2004

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DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity.
Qianxing Mo, Shi-Fang Lu, Shan Hu, Neal G Simon

Brain Res Mol Brain Res· July 2004

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Increased aggressive behavior and decreased affiliative behavior in adult male monkeys after long-term consumption of diets rich in soy protein and isoflavones.
Neal G Simon, Jay R Kaplan, Shan Hu, Thomas C Register, Michael R Adams

Horm Behav· April 2004

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