Publications by authors named "Neel Madhukar"

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CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement.
Prashant V Thakkar, Katsuhiro Kita, Urko Del Castillo, Giuseppe Galletti, Neel Madhukar

Dev Cell· December 2021

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Correction: Discovery and clinical introduction of first-in-class imipridone ONC201.
Joshua E Allen, C Leah B Kline, Varun V Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar

Oncotarget· October 2021

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Artificial Intelligence in Cancer Research and Precision Medicine.
Bhavneet Bhinder, Coryandar Gilvary, Neel S Madhukar, Olivier Elemento

Cancer Discov· April 2021

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A machine learning and network framework to discover new indications for small molecules.
Coryandar Gilvary, Jamal Elkhader, Neel Madhukar, Claire Henchcliffe, Marcus D Goncalves

PLoS Comput Biol· August 2020

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Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia.
Takenobu Nii, Varun V Prabhu, Vivian Ruvolo, Neel Madhukar, Ran Zhao

Leukemia· December 2019

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A Bayesian machine learning approach for drug target identification using diverse data types.
Neel S Madhukar, Prashant K Khade, Linda Huang, Kaitlyn Gayvert, Giuseppe Galletti

Nat Commun· November 2019

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The Missing Pieces of Artificial Intelligence in Medicine.
Coryandar Gilvary, Neel Madhukar, Jamal Elkhader, Olivier Elemento

Trends Pharmacol Sci· August 2019

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Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism.
Varun V Prabhu, Neel S Madhukar, Coryandar Gilvary, C Leah B Kline, Sophie Oster

Clin Cancer Res· April 2019

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Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing.
Neel S Madhukar, Olivier Elemento

Methods Mol Biol· October 2018

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Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
Varun V Prabhu, Amriti R Lulla, Neel S Madhukar, Marie D Ralff, Dan Zhao

PLoS One· October 2017

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A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.
Maria V Liberti, Ziwei Dai, Suzanne E Wardell, Joshua A Baccile, Xiaojing Liu, Neel S Madhukar

Cell Metab· October 2017

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Discovery and clinical introduction of first-in-class imipridone ONC201.
Joshua E Allen, C Leah B Kline, Varun V Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar

Oncotarget· November 2016

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A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.
Kaitlyn M Gayvert, Neel S Madhukar, Olivier Elemento

Cell Chem Biol· October 2016

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Organization of enzyme concentration across the metabolic network in cancer cells.
Neel S Madhukar, Marc O Warmoes, Jason W Locasale

PLoS One· January 2016

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Prediction of Genetic Interactions Using Machine Learning and Network Properties.
Neel S Madhukar, Olivier Elemento, Gaurav Pandey

Front Bioeng Biotechnol· November 2015

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Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
Himisha Beltran, Kenneth Eng, Juan Miguel Mosquera, Alexandros Sigaras, Alessandro Romanel, Neel Madhukar

JAMA Oncol· July 2015

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