Publications by authors named "Neil Mathews"

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Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
G Stuart Cockerill, Richard M Angell, Alexandre Bedernjak, Irina Chuckowree, Ian Fraser, Neil Mathews

J Med Chem· April 2021

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A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein.
John DeVincenzo, Dereck Tait, John Efthimiou, Julie Mori, Young-In Kim, Neil Mathews

Antimicrob Agents Chemother· January 2020

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State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.
G Stuart Cockerill, James A D Good, Neil Mathews

J Med Chem· April 2019

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Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Martin E Swarbrick, Paul J Beswick, Robert J Gleave, Richard H Green, Sharon Bingham, Neil Mathews

Bioorg Med Chem Lett· August 2009

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Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Paul J Beswick, Andrew P Blackaby, Chas Bountra, Terry Brown, Kerry Browning, Neil Mathews

Bioorg Med Chem Lett· August 2009

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Discovery of 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): a potent, selective, and orally active transforming growth factor-beta type I receptor inhibitor.
Françoise Gellibert, Anne-Charlotte de Gouville, James Woolven, Neil Mathews, Van-Loc Nguyen

J Med Chem· April 2006

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Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.
Paul Beswick, Sharon Bingham, Chas Bountra, Terry Brown, Kerry Browning, Neil Mathews

Bioorg Med Chem Lett· November 2004

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Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors.
Françoise Gellibert, James Woolven, Marie-Hélène Fouchet, Neil Mathews, Helen Goodland

J Med Chem· August 2004

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