Publications by authors named "James A D Good"

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Design, Synthesis, and Evaluation of Novel Δ-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mutant.
Souvik Sarkar, Anne E Mayer Bridwell, James A D Good, Erin R Wang, Samuel R McKee

J Med Chem· August 2023

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Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
G Stuart Cockerill, Richard M Angell, Alexandre Bedernjak, Irina Chuckowree, Ian Fraser, James A D Good

J Med Chem· April 2021

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Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based inhibitors.
Martina Kulén, Carlos Núñez-Otero, Andrew G Cairns, Jim Silver, Anders E G Lindgren, James A D Good

Medchemcomm· November 2019

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Chemical disarming of isoniazid resistance in .
Kelly Flentie, Gregory A Harrison, Hasan Tükenmez, Jonathan Livny, James A D Good

Proc Natl Acad Sci U S A· May 2019

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State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.
G Stuart Cockerill, James A D Good, Neil Mathews

J Med Chem· April 2019

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Thiazolino 2-Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity.
James A D Good, Martina Kulén, Jim Silver, K Syam Krishnan, Wael Bahnan

J Med Chem· November 2017

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Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens.
Carrie L Shaffer, James A D Good, Santosh Kumar, K Syam Krishnan, Jennifer A Gaddy

mBio· April 2016

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Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity.
James A D Good, Jim Silver, Carlos Núñez-Otero, Wael Bahnan, K Syam Krishnan

J Med Chem· March 2016

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Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.
James A D Good, Christopher Andersson, Sabine Hansen, Jessica Wall, K Syam Krishnan

Cell Chem Biol· March 2016

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Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili.
Kyle A Floyd, Jessica L Moore, Allison R Eberly, James A D Good, Carrie L Shaffer

PLoS Pathog· March 2015

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Synthesis of fluorescent ring-fused 2-pyridone peptidomimetics.
K Syam Krishnan, Christoffer Bengtsson, James A D Good, Shamil Mirkhanov, Erik Chorell

J Org Chem· December 2013

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Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models.
James A D Good, Fang Wang, Oliver Rath, Hung Yi Kristal Kaan, Sandeep K Talapatra

J Med Chem· March 2013

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Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.
Murad N Abualhasan, James A D Good, Kitiyaporn Wittayanarakul, Nahoum G Anthony, Giacomo Berretta

Eur J Med Chem· August 2012

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Triphenylbutanamines: kinesin spindle protein inhibitors with in vivo antitumor activity.
Fang Wang, James A D Good, Oliver Rath, Hung Yi Kristal Kaan, Oliver B Sutcliffe

J Med Chem· February 2012

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Elucidating the functionality of kinesins: an overview of small molecule inhibitors.
James A D Good, Dimitrios A Skoufias, Frank Kozielski

Semin Cell Dev Biol· December 2011

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