Publications by authors named "Neil Osheroff"

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Activities of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284 against the Biothreat Pathogen and Its Type II Topoisomerases.
Chelsea A Mann, Stephanie A Halasohoris, Annette M Gray, Jennifer Chua, Jade L Spencer, Neil Osheroff

ACS Infect Dis· December 2025

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Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against Gyrase and Topoisomerase IV in Cells and In Vitro.
Alexandria A Oviatt, Jessica A Collins, Chelsea A Mann, Jianzhong Huang, Karen Mattern, Neil Osheroff

ACS Infect Dis· November 2025

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Bacterial type II topoisomerases cleave DNA in a species-specific manner.
Ian L Morgan, Jeffrey Y Jian, Neil Osheroff, Keir C Neuman

bioRxiv· July 2025

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DNA Supercoiling Catalyzed by Bacterial Gyrase.
Samika Joshi, Neil Osheroff

Methods Mol Biol· May 2025

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DNA Decatenation Catalyzed by Bacterial Topoisomerase IV.
Jillian F Armenia, Neil Osheroff

Methods Mol Biol· May 2025

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DNA Cleavage Mediated by Bacterial Type II Topoisomerases.
Chelsea A Mann, Neil Osheroff

Methods Mol Biol· May 2025

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Tips and Best Practices in Medical Education: Integrating Foundational and Clinical Sciences across the Medical Curriculum.
Neil Osheroff

Asia Pac Sch· April 2025

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Anti-Mycobacterial Activity of Bacterial Topoisomerase Inhibitors with Dioxygenated Linkers.
Mark J Mitton-Fry, Jason E Cummings, Yanran Lu, Jillian F Armenia, Jo Ann W Byl, Neil Osheroff

ACS Infect Dis· February 2025

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Interactions between Zoliflodacin and Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting.
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff

ACS Infect Dis· August 2024

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Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening.
Joshua W Powell, Chelsea A Mann, Paul D Toth, Sheri Nolan, Anja Steinert, Neil Osheroff

ACS Med Chem Lett· August 2024

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Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance.
Jessica A Collins, Neil Osheroff

ACS Infect Dis· April 2024

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Target-Mediated Fluoroquinolone Resistance in : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV.
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff

ACS Infect Dis· April 2024

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Interactions between Gepotidacin and Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting.
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Neil Osheroff

ACS Infect Dis· April 2024

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Professional Identity Formation of Medical Science Educators: An Imperative for Academic Medicine.
Aviad Haramati, Giulia Bonaminio, Neil Osheroff

Med Sci Educ· February 2024

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Professional Identity Formation of Basic Science Medical Educators: A Qualitative Study of Identity Supports and Threats.
Joanna Veazey Brooks, Bonny L Dickinson, Kelly M Quesnelle, Giulia A Bonaminio, Janine Chalk-Wilayto, Neil Osheroff

Acad Med· November 2023

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No Time to Relax and Unwind: Exploration of Topoisomerases and a Growing Field of Study.
Joseph E Deweese, Neil Osheroff

Int J Mol Sci· August 2023

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Telling Your Right Hand from Your Left: The Effects of DNA Supercoil Handedness on the Actions of Type II Topoisomerases.
Jeffrey Y Jian, Neil Osheroff

Int J Mol Sci· July 2023

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Actions of a Novel Bacterial Topoisomerase Inhibitor against Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks.
Soziema E Dauda, Jessica A Collins, Jo Ann W Byl, Yanran Lu, Jack C Yalowich, Neil Osheroff

Int J Mol Sci· July 2023

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Basis for the discrimination of supercoil handedness during DNA cleavage by human and bacterial type II topoisomerases.
Jeffrey Y Jian, Kevin D McCarty, Jo Ann W Byl, F Peter Guengerich, Keir C Neuman, Neil Osheroff

Nucleic Acids Res· May 2023

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A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Gyrase.
Jo Ann W Byl, Rudolf Mueller, Ben Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff

ACS Infect Dis· March 2023

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Recognition of DNA Supercoil Handedness during Catenation Catalyzed by Type II Topoisomerases.
Esha D Dalvie, Jordan C Stacy, Keir C Neuman, Neil Osheroff

Biochemistry· October 2022

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Zooming into the COVID Era Together.
Emily C Bird, Cathleen C Pettepher, Madeleine A Z Ball, Pulak Goswami, Eden Lyons, Neil Osheroff

Med Sci Educ· October 2022

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Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms.
Sabrina X Van Ravenstein, Kavi P Mehta, Tamar Kavlashvili, Jo Ann W Byl, Runxiang Zhao, Neil Osheroff

EMBO J· June 2022

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1,3-Dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Expanding Structural Diversity and the Antibacterial Spectrum.
Yanran Lu, Chelsea A Mann, Sheri Nolan, Jessica A Collins, Elizabeth Parker, Neil Osheroff

ACS Med Chem Lett· June 2022

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Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.
Preshendren Govender, Rudolf Müller, Kawaljit Singh, Virsinha Reddy, Charles J Eyermann, Neil Osheroff

J Med Chem· May 2022

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