Publications by authors named "Neil R Mathias"

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Utilization of In Vitro, In Vivo and In Silico Tools to Evaluate the pH-Dependent Absorption of a BCS Class II Compound and Identify a pH-Effect Mitigating Strategy.
Christoph Gesenberg, Neil R Mathias, Yan Xu, John Crison, Ishani Savant

Pharm Res· October 2019

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Assessing the risk of pH-dependent absorption for new molecular entities: a novel in vitro dissolution test, physicochemical analysis, and risk assessment strategy.
Neil R Mathias, Yan Xu, Dhaval Patel, Michael Grass, Brett Caldwell

Mol Pharm· November 2013

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The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2.
Xiaojun Han, Rita L Civiello, Charles M Conway, Deborah A Cook, Carl D Davis, Neil R Mathias

Bioorg Med Chem Lett· March 2013

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The use of modeling tools to drive efficient oral product design.
Neil R Mathias, John Crison

AAPS J· September 2012

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Non-invasive systemic drug delivery: developability considerations for alternate routes of administration.
Neil R Mathias, Munir A Hussain

J Pharm Sci· January 2010

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Rat nasal lavage biomarkers to assess preclinical irritation potential of nasal drug formulations and excipients.
Neil R Mathias, Paul Moench, Christopher Heran, Munir A Hussain, Ronald L Smith

J Pharm Sci· February 2009

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Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure.
Andrew P Degnan, Prasad V Chaturvedula, Charles M Conway, Deborah A Cook, Carl D Davis, Neil R Mathias

J Med Chem· August 2008

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Modulation of tight junctions does not predict oral absorption of hydrophilic compounds: use of Caco-2 and Calu-3 cells.
Amrita V Kamath, Richard A Morrison, Neil R Mathias, Sandra A Dando, Anthony M Marino

Arch Pharm Res· August 2007

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Nucleoside transport in primary cultured rabbit tracheal epithelial cells.
Neil R Mathias, Sharon K Wu, Kwang-Jin Kim, Vincent H L Lee

J Drug Target· March 2006

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Carbopol-mediated paracellular transport enhancement in Calu-3 cell layers.
Lianli Li, Neil R Mathias, Christopher L Heran, Paul Moench, Doris A Wall

J Pharm Sci· February 2006

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A rabbit model for sublingual drug delivery: comparison with human pharmacokinetic studies of propranolol, verapamil and captopril.
Manisha M Dali, Paul A Moench, Neil R Mathias, Paul I Stetsko, Christopher L Heran

J Pharm Sci· January 2006

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Functional and pharmacological mechanisms of nucleoside transport across the basolateral membrane of rabbit tracheal epithelial cells.
Sharon K Wu, Neil R Mathias, Kwang-Jin Kim, Vincent H L Lee

Life Sci· December 2005

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The effect of anesthesia on the pharmacokinetics of sublingually administered verapamil in rabbits.
Paul A Moench, Christopher L Heran, Paul I Stetsko, Neil R Mathias, Doris A Wall

J Pharm Sci· September 2003

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