Publications by authors named "Neil S Ryder"

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High-Throughput Screen for Inhibitors of Virulence Using a Co-Culture Surrogate Host Model.
Angela L Woods, David Parker, Meir M Glick, Yunshan Peng, Francois Lenoir, Neil S Ryder

ACS Omega· February 2022

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Involvement of heat shock proteins in Candida albicans biofilm formation.
Marco Becherelli, Jianshi Tao, Neil S Ryder

J Mol Microbiol Biotechnol· June 2014

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Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents.
Daryl L Richie, Katherine V Thompson, Christian Studer, Vivian C Prindle, Thomas Aust, Neil S Ryder

Antimicrob Agents Chemother· May 2013

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An integrated approach for identification and target validation of antifungal compounds active against Erg11p.
Dominic Hoepfner, Shantanu Karkare, Stephen B Helliwell, Martin Pfeifer, Markus Trunzer, Neil S Ryder

Antimicrob Agents Chemother· August 2012

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Biophysical investigation of the mode of inhibition of tetramic acids, the allosteric inhibitors of undecaprenyl pyrophosphate synthase.
Lac V Lee, Brian Granda, Karl Dean, Jianshi Tao, Eugene Liu, Neil S Ryder

Biochemistry· June 2010

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Discontinued drugs in 2008: anti-infectives.
Neil S Ryder

Expert Opin Investig Drugs· January 2010

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In vivo characterization of the peptide deformylase inhibitor LBM415 in murine infection models.
Colin S Osborne, Georg Neckermann, Evelin Fischer, Robert Pecanka, Donghui Yu, Neil S Ryder

Antimicrob Agents Chemother· September 2009

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Discontinued drugs in 2007: anti-infectives.
Neil S Ryder

Expert Opin Investig Drugs· January 2009

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Discontinued drugs in 2006: anti-infectives.
Neil S Ryder

Expert Opin Investig Drugs· December 2007

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Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number.
Charles R Dean, Shubha Narayan, Joel Richards, Denis M Daigle, Stacy Esterow, Neil S Ryder

Antimicrob Agents Chemother· March 2007

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Peptide deformylase inhibitors as potent antimycobacterial agents.
Jeanette W P Teo, Pamela Thayalan, David Beer, Amelia S L Yap, Mahesh Nanjundappa, Neil S Ryder

Antimicrob Agents Chemother· November 2006

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NIM811, a cyclophilin inhibitor, exhibits potent in vitro activity against hepatitis C virus alone or in combination with alpha interferon.
Sue Ma, Joanna E Boerner, ChoiLai TiongYip, Beat Weidmann, Neil S Ryder

Antimicrob Agents Chemother· September 2006

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Biological, biochemical, and molecular characterization of a new clinical Trichophyton rubrum isolate resistant to terbinafine.
Colin S Osborne, Ingrid Leitner, Bettina Hofbauer, Ceri A Fielding, Bertrand Favre, Neil S Ryder

Antimicrob Agents Chemother· June 2006

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Combination therapy with terbinafine and amphotericin B in a rabbit model of experimental invasive aspergillosis.
William R Kirkpatrick, Ana C Vallor, Robert K McAtee, Neil S Ryder, Annette W Fothergill

Antimicrob Agents Chemother· November 2005

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Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415.
Charles R Dean, Shubha Narayan, Denis M Daigle, JoAnn L Dzink-Fox, Xiaoling Puyang, Neil S Ryder

Antimicrob Agents Chemother· August 2005

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Amino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine.
Colin S Osborne, Ingrid Leitner, Bertrand Favre, Neil S Ryder

Antimicrob Agents Chemother· July 2005

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Exploring the antibacterial and hemolytic activity of shorter- and longer-chain beta-, alpha,beta-, and gamma-peptides, and of beta-peptides from beta2-3-aza- and beta3-2-methylidene-amino acids bearing proteinogenic side chains--a survey.
Per I Arvidsson, Neil S Ryder, H Markus Weiss, David F Hook, Jaime Escalante

Chem Biodivers· March 2005

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Biochemical characterization of terbinafine-resistant Trichophyton rubrum isolates.
Bertrand Favre, Mahmoud A Ghannoum, Neil S Ryder

Med Mycol· December 2004

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Identification of novel potent bicyclic peptide deformylase inhibitors.
Valentina Molteni, Xiaohui He, Juliet Nabakka, Kunyong Yang, Andreas Kreusch, Neil S Ryder

Bioorg Med Chem Lett· March 2004

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Chemical and biological investigations of beta-oligoarginines.
Dieter Seebach, Kenji Namoto, Yogesh R Mahajan, Pascal Bindschädler, Reiner Sustmann, Neil S Ryder

Chem Biodivers· January 2004

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Antibiotic and hemolytic activity of a beta2/beta3 peptide capable of folding into a 12/10-helical secondary structure.
Per I Arvidsson, Neil S Ryder, H Markus Weiss, Gerhard Gross, Olivier Kretz

Chembiochem· December 2003

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In vitro analysis of the ability of Trichophyton rubrum to become resistant to terbinafine.
Colin S Osborne, Bettina Hofbauer, Bertrand Favre, Neil S Ryder

Antimicrob Agents Chemother· November 2003

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Comparison of in vitro activities of 17 antifungal drugs against a panel of 20 dermatophytes by using a microdilution assay.
Bertrand Favre, Bettina Hofbauer, Kwang-Soo Hildering, Neil S Ryder

J Clin Microbiol· October 2003

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Novel high energy intermediate analogues with a triazasterol structure as potential ergosterol biosynthesis inhibitors IV: antimicrobial activity of mono-, bi-, and tricyclic 8, 13, 15-triazasteroid analogues including the synthesis of novel 4-alkylamino- and 4-alkenylamino-9-hydroxypyrimidoisoquinolines.
Edith Gössnitzer, Asbjörn Punkenhofer, Neil S Ryder

Arch Pharm (Weinheim)· August 2003

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Novel high energy intermediate analogues with triazasterol-related structures as inhibitors of ergosterol biosynthesis. Part I: synthesis and antifungal activity of N-alkyl-N'-(phenethyl- and cyclohexenylethyl)guanidines and N2-substituted 2-imidazolinamines.
Edith Gössnitzer, Roland Malli, Silvia Schuster, Bertrand Favre, Neil S Ryder

Arch Pharm (Weinheim)· April 2003

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