Publications by authors named "Nicholas Clayton"

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Beyond ASPECTS: A Practical Guide to CT Perfusion Interpretation.
Raphael Miller, Ryan Morasse, Nicholas Clayton, Ashley Park, Anna Tarasova

Neuroradiol J· October 2025

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Histone acetylation, BET proteins, and periodontal inflammation.
Nicholas Clayton, David Pellei, Zhao Lin

Mol Oral Microbiol· August 2024

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Selective BET inhibitor RVX-208 ameliorates periodontal inflammation and bone loss.
Mingxu Sun, Nicholas Clayton, Sheikh Alam, Niels Asmussen, Andrew Wong

J Clin Periodontol· December 2023

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Stress Ulcer Prophylaxis in Cardiac Surgery: A Retrospective Cohort Study to Analyze the Effects of SUP Cessation.
Andrew Mekhail, Paul Young, Ann-Marie Mekhail, Georges Tinawi, Cheyaanthan Haran, Nicholas Clayton

J Intensive Care Med· October 2023

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Utilizing retrograde autologous priming for blood conservation in cardiac surgery.
Andrew Mekhail, Nicholas Clayton, Kamaraj Rhadakrishnan, Amber Blakey, Sean Galvin

ANZ J Surg· October 2023

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High-resolution and high-sensitivity PET for quantitative molecular imaging of the monoaminergic nuclei: A GATE simulation study.
Zipai Wang, Xinjie Cao, Andy LaBella, Xinjie Zeng, Anat Biegon, Nicholas Clayton

Med Phys· July 2022

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and Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens.
Nicholas P Clayton, Akash Jain, Stephanie A Halasohoris, Lisa M Pysz, Sanae Lembirik

Antimicrob Agents Chemother· May 2021

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Sargramostim (rhu GM-CSF) Improves Survival of Non-Human Primates with Severe Bone Marrow Suppression after Acute, High-Dose, Whole-Body Irradiation.
Nicholas P Clayton, Richard C Khan-Malek, Charles A Dangler, Donghui Zhang, Alexis Ascah

Radiat Res· February 2021

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A chip-based potentiometric sensor for a Zika virus diagnostic using 3D surface molecular imprinting.
Vincent Ricotta, Yingjie Yu, Nicholas Clayton, Ya-Chen Chuang, Yantian Wang

Analyst· July 2019

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An integrative systems approach identifies novel candidates in Marfan syndrome-related pathophysiology.
Raghu Bhushan, Lukas Altinbas, Marten Jäger, Marcin Zaradzki, Daniel Lehmann, Nicholas P Clayton

J Cell Mol Med· April 2019

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Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP receptor partial agonist for the treatment of pain.
Mark P Healy, Amanda C Allan, Kristin Bailey, Andy Billinton, Iain P Chessell, Nicholas M Clayton

Bioorg Med Chem Lett· June 2018

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Clinical Case Of the Month: A 35 Year Old Woman with Abdominal Pain.
Melissa Spera, Camille Thelin, Abby Gandolfi, Nicholas Clayton, Karl M Nettles

J La State Med Soc· September 2017

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Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics.
Jennifer Cj Chen, Oliver D King, Yuanfan Zhang, Nicholas P Clayton, Carrie Spencer

Mol Ther· August 2016

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Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche.
Silvia Smaldone, Nicholas P Clayton, Maria del Solar, Gemma Pascual, Seng H Cheng

J Bone Miner Res· January 2016

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Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.
Jason R Cook, Nicholas P Clayton, Luca Carta, Josephine Galatioto, Emily Chiu

Arterioscler Thromb Vasc Biol· April 2015

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Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease.
Nicholas P Clayton, Carol A Nelson, Timothy Weeden, Kristin M Taylor, Rodney J Moreland

Mol Ther Nucleic Acids· October 2014

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Fabrication, characterization, and energetic properties of metallized fibers.
Nicholas A Clayton, Keerti S Kappagantula, Michelle L Pantoya, Sharon C Kettwich, Scott T Iacono

ACS Appl Mater Interfaces· May 2014

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Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy.
Andrew J Leger, Leocadia M Mosquea, Nicholas P Clayton, I-Huan Wu, Timothy Weeden

Nucleic Acid Ther· April 2013

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Inhibiting TGF-β activity improves respiratory function in mdx mice.
Carol A Nelson, R Bridge Hunter, Lindsay A Quigley, Stefan Girgenrath, William D Weber, Nicholas P Clayton

Am J Pathol· June 2011

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Discovery of sodium 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (GSK269984A) an EP(1) receptor antagonist for the treatment of inflammatory pain.
Adrian Hall, Andy Billinton, Susan H Brown, Anita Chowdhury, Nicholas M Clayton

Bioorg Med Chem Lett· May 2009

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Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.
Adrian Hall, Susan H Brown, Christopher Budd, Nicholas M Clayton, Gerard M P Giblin

Bioorg Med Chem Lett· January 2009

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Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy.
Adrian Hall, Andy Billinton, Susan H Brown, Nicholas M Clayton, Anita Chowdhury

Bioorg Med Chem Lett· June 2008

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1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists: Structure-activity relationships of 4- and 5-substituted benzoic acid derivatives.
Adrian Hall, Susan H Brown, Iain P Chessell, Anita Chowdhury, Nicholas M Clayton

Bioorg Med Chem Lett· February 2007

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1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. Structure-activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives.
Adrian Hall, Susan H Brown, Iain P Chessell, Anita Chowdhury, Nicholas M Clayton

Bioorg Med Chem Lett· February 2007

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The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.
Gerard M P Giblin, Rino A Bit, Susan H Brown, Hélène M Chaignot, Anita Chowdhury, Nicholas M Clayton

Bioorg Med Chem Lett· January 2007

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