Publications by authors named "Nicholas D Klemen"

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Selective expansion of T-cell receptor engineered T cells with increased stem-like phenotypes using neoantigen stimulation.
Sanghyun P Kim, Noam Levin, Youngseo Jo, Charles Marquardt, Zhiya Yu, Nicholas D Klemen

J Immunother Cancer· December 2025

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Is Low Compliance a Red Flag or a Rational Rejection of Extended Venous Thromboembolism Prophylaxis?
Lauren Weaver, Alexander Troester, Imran Hassan, Nicholas D Klemen, Paolo Goffredo

Dis Colon Rectum· October 2025

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Adoptive Cell Transfer of Tumor-Infiltrating Lymphocytes for Metastatic Acral Lentiginous Melanoma.
Paul H McClelland, Shirley K Nah, Alexandra M Gustafson, Aaron J Dinerman, Bradley S White, Nicholas D Klemen

J Clin Oncol· August 2025

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A platform for multisite immune profiling of premetastatic pancreatic cancer at single-cell resolution.
Elishama N Kanu, Ashley A Fletcher, Jiayin Bao, Ethan S Agritelley, Julia Button, Nicholas D Klemen

Cancer Immunol Immunother· August 2025

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Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial.
Frank J Lowery, Stephanie L Goff, Billel Gasmi, Maria R Parkhurst, Nivedita M Ratnam, Nicholas D Klemen

Nat Med· June 2025

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Publisher Correction: Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial.
Frank J Lowery, Stephanie L Goff, Billel Gasmi, Maria R Parkhurst, Nivedita M Ratnam, Nicholas D Klemen

Nat Med· June 2025

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Clinical factors associated with growth and neoantigen reactivity of tumor infiltrating lymphocytes from metastatic epithelial cancers.
Alexandra M Gustafson, Aaron J Dinerman, Kyle J Hitscherich, Maria R Parkhurst, Hyunmi Halas, Nicholas D Klemen

Cancer Immunol Immunother· June 2025

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Rapid enrichment of progenitor exhausted neoantigen-specific CD8 T cells from peripheral blood.
Mamduh Khateb, Raina Jung, Stav Leibou, Patrick Hadley, Zhiya Yu, Nicholas D Klemen

bioRxiv· May 2025

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Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results.
Maria Parkhurst, Stephanie L Goff, Frank J Lowery, Rachel K Beyer, Hyunmi Halas, Nicholas D Klemen

Nat Med· September 2024

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Results of the TARGET-TP Randomized Clinical Trial.
Aaron J Dinerman, Nicholas D Klemen

JAMA Oncol· July 2024

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Thrombotic and Hemorrhagic Outcomes After Elective Surgery in Preoperatively Anticoagulated Patients.
Chi Zhang, Katherine Bews, Nicholas D Klemen, David Etzioni, Elizabeth B Habermann

Mayo Clin Proc· July 2024

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ASO Author Reflections: How Immunotherapy Could Change the Management of Responsive Solid Tumors.
Nicholas D Klemen, Michael I D'Angelica

Ann Surg Oncol· December 2022

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Local Therapy for Oligoprogression or Consolidation in High Mutational Burden Stage 4 Colorectal Cancer Treated With PD-1 or PD-L1 Blockade.
Nicholas D Klemen, Colin M Court, Maria Clara Fernandes, Henry S Walch, Walid K Chatila

Ann Surg Oncol· December 2022

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Reply to R.A. Snyder et al.
Nicholas D Klemen, Paul L Feingold, Barry Hashimoto

J Clin Oncol· August 2022

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Prevention of Anal Cancer.
Paolo Goffredo, Nicholas D Klemen, Imran Hassan

N Engl J Med· August 2022

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Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma.
Nicholas D Klemen, Sinchun Hwang, Martina Bradic, Evan Rosenbaum, Mark A Dickson

Clin Cancer Res· March 2022

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How Strong Is the Evidence Supporting Thromboprophylaxis in Surgical Oncology?
Nicholas D Klemen, Paul L Feingold, Barry Hashimoto

J Clin Oncol· February 2022

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The emerging role of immunotherapy for the treatment of sarcoma.
Nicholas D Klemen, Ciara M Kelly, Edmund K Bartlett

J Surg Oncol· March 2021

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Mortality benefits of thromboprophylaxis - Authors' reply.
Nicholas D Klemen, Paul L Feingold, Barry Hashimoto, Cary P Gross, Kevin Y Pei

Lancet Haematol· November 2020

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Mortality risk associated with venous thromboembolism: a systematic review and Bayesian meta-analysis.
Nicholas D Klemen, Paul L Feingold, Barry Hashimoto, Melinda Wang, Svetlana Kleyman

Lancet Haematol· August 2020

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Survival after checkpoint inhibitors for metastatic acral, mucosal and uveal melanoma.
Nicholas D Klemen, Melinda Wang, Jill C Rubinstein, Kelly Olino, James Clune

J Immunother Cancer· March 2020

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A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants.
Raul Vizcardo, S M Rafiqul Islam, Takuya Maeda, Naritaka Tamaoki, Meghan L Good, Nicholas D Klemen

J Vis Exp· August 2019

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Role of Surgery in Combination with Immunotherapy.
Nicholas D Klemen, Mackenzie L Shindorf, Richard M Sherry

Surg Oncol Clin N Am· July 2019

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Patterns of failure after immunotherapy with checkpoint inhibitors predict durable progression-free survival after local therapy for metastatic melanoma.
Nicholas D Klemen, Melinda Wang, Paul L Feingold, Kirsten Cooper, Sabrina N Pavri

J Immunother Cancer· July 2019

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Completion lymphadenectomy for a positive sentinel node biopsy in melanoma patients is not associated with a survival benefit.
Nicholas D Klemen, Gang Han, Stanley P Leong, Mohammed Kashani-Sabet, John Vetto

J Surg Oncol· June 2019

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