Publications by authors named "Nicholas D Oakes"

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Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats.
Tobias Kroon, Therese Hagstedt, Ida Alexandersson, Annett Ferm, Marie Petersson, Nicholas D Oakes

Sci Transl Med· October 2022

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The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis.
Kristina Wallenius, Tobias Kroon, Therese Hagstedt, Lars Löfgren, Maria Sörhede-Winzell, Nicholas D Oakes

J Lipid Res· March 2022

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Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid (DHA) in the rat.
Anna Lindblom, Cecilia Ericsson, Therese Hagstedt, Ann Kjellstedt, Jan Oscarsson, Nicholas D Oakes

PLoS One· January 2019

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Involvement of the metabolic sensor GPR81 in cardiovascular control.
Kristina Wallenius, Pia Thalén, Jan-Arne Björkman, Petra Johannesson, John Wiseman, Nicholas D Oakes

JCI Insight· October 2017

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Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments.
Robert Andersson, Tobias Kroon, Joachim Almquist, Mats Jirstrand, Nicholas D Oakes

J Pharmacokinet Pharmacodyn· June 2017

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Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats[S].
Tobias Kroon, Tania Baccega, Arne Olsén, Johan Gabrielsson, Nicholas D Oakes

J Lipid Res· January 2017

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Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats.
Tobias Kroon, Ann Kjellstedt, Pia Thalén, Johan Gabrielsson, Nicholas D Oakes

J Lipid Res· September 2015

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Pharmacological PPARα activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat.
Anette Ericsson, Nigel Turner, Göran I Hansson, Kristina Wallenius, Nicholas D Oakes

PLoS One· August 2015

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The PPAR α / γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat.
Kristina Wallenius, Ann Kjellstedt, Pia Thalén, Lars Löfgren, Nicholas D Oakes

PPAR Res· November 2013

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Roles of Fatty Acid oversupply and impaired oxidation in lipid accumulation in tissues of obese rats.
Nicholas D Oakes, Ann Kjellstedt, Pia Thalén, Bengt Ljung, Nigel Turner

J Lipids· June 2013

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Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat.
Kashif Sheikh, Germán Camejo, Boel Lanne, Torbjörn Halvarsson, Marie Rydén Landergren, Nicholas D Oakes

Am J Physiol Endocrinol Metab· April 2007

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Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes.
Nicholas D Oakes, Pia Thalén, Ellen Aasum, Amanda Edgley, Terje Larsen

Am J Physiol Endocrinol Metab· May 2006

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PPARgamma agonist induced cardiac enlargement is associated with reduced fatty acid and increased glucose utilization in myocardium of Wistar rats.
Amanda J Edgley, Pia G Thalén, Björn Dahllöf, Boel Lanne, Bengt Ljung, Nicholas D Oakes

Eur J Pharmacol· May 2006

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Tesaglitazar, a dual PPAR{alpha}/{gamma} agonist, ameliorates glucose and lipid intolerance in obese Zucker rats.
Nicholas D Oakes, Pia Thalén, Therese Hultstrand, Severina Jacinto, Germán Camejo

Am J Physiol Regul Integr Comp Physiol· October 2005

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Peroxisome proliferator-activated receptor (PPAR) activation induces tissue-specific effects on fatty acid uptake and metabolism in vivo--a study using the novel PPARalpha/gamma agonist tesaglitazar.
Bronwyn D Hegarty, Stuart M Furler, Nicholas D Oakes, Edward W Kraegen, Gregory J Cooney

Endocrinology· July 2004

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AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats.
Bengt Ljung, Krister Bamberg, Björn Dahllöf, Ann Kjellstedt, Nicholas D Oakes

J Lipid Res· November 2002

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Correction of dysfunctional fatty acid metabolism using peroxisome proliferator activated receptor gamma agonists.
Nicholas D Oakes, Bengt Ljung, Germán Camejo

J R Soc Med· September 2002

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Evaluation of free fatty acid metabolism in vivo.
Nicholas D Oakes, Stuart M Furler

Ann N Y Acad Sci· June 2002

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