Publications by authors named "Johan Gabrielsson"

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Turn On, Tune In, Turnover! Target Biology Impacts In Vivo Potency, Efficacy, and Clearance.
Johan Gabrielsson, Stephan Hjorth

Pharmacol Rev· May 2023

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Model-based assessment of combination therapies - ranking of radiosensitizing agents in oncology.
Marcus Baaz, Tim Cardilin, Floriane Lignet, Astrid Zimmermann, Samer El Bawab, Johan Gabrielsson

BMC Cancer· May 2023

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Exposure-response modeling improves selection of radiation and radiosensitizer combinations.
Tim Cardilin, Joachim Almquist, Mats Jirstrand, Astrid Zimmermann, Floriane Lignet, Johan Gabrielsson

J Pharmacokinet Pharmacodyn· April 2022

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Impact of enzyme turnover on the dynamics of the Michaelis-Menten model.
Lambertus A Peletier, Johan Gabrielsson

Math Biosci· April 2022

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Comparisons of basic target-mediated drug disposition (TMDD) and ligand facilitated target removal (LFTR).
Lambertus A Peletier, Rasmus Jansson-Löfmark, Johan Gabrielsson

Eur J Pharm Sci· July 2021

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An Integrative Approach for Improved Assessment of Cardiovascular Safety Data.
Mikael Wallman, Stefan Scheuerer, Eric Martel, Nicolas Pairet, Mats Jirstrand, Johan Gabrielsson

J Pharmacol Exp Ther· May 2021

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Does In Vitro Potency Predict Clinically Efficacious Concentrations?
Rasmus Jansson-Löfmark, Stephan Hjorth, Johan Gabrielsson

Clin Pharmacol Ther· August 2020

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Challenge model of TNF turnover at varying LPS and drug provocations.
Felix Held, Edmund Hoppe, Marija Cvijovic, Mats Jirstrand, Johan Gabrielsson

J Pharmacokinet Pharmacodyn· June 2019

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Modeling long-term tumor growth and kill after combinations of radiation and radiosensitizing agents.
Tim Cardilin, Joachim Almquist, Mats Jirstrand, Astrid Zimmermann, Floriane Lignet, Johan Gabrielsson

Cancer Chemother Pharmacol· June 2019

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Challenging the dose-response-time data approach: Analysis of a complex system.
Robert Andersson, Mats Jirstrand, Joachim Almquist, Johan Gabrielsson

Eur J Pharm Sci· February 2019

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Modelling of oscillatory cortisol response in horses using a Bayesian population approach for evaluation of dexamethasone suppression test protocols.
Felix Held, Carl Ekstrand, Marija Cvijovic, Johan Gabrielsson, Mats Jirstrand

J Pharmacokinet Pharmacodyn· February 2019

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Dose-Response-Time Data Analysis: An Underexploited Trinity.
Johan Gabrielsson, Robert Andersson, Mats Jirstrand, Stephan Hjorth

Pharmacol Rev· January 2019

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Evaluation and translation of combination therapies in oncology - A quantitative approach.
Tim Cardilin, Joachim Almquist, Mats Jirstrand, Johan Gabrielsson

Eur J Pharmacol· September 2018

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Lost in translation: What's in an EC? Innovative PK/PD reasoning in the drug development context.
Johan Gabrielsson, Lambertus A Peletier, Stephan Hjorth

Eur J Pharmacol· September 2018

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Michaelis-Menten from an In Vivo Perspective: Open Versus Closed Systems.
Johan Gabrielsson, Lambertus A Peletier

AAPS J· September 2018

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New Equilibrium Models of Drug-Receptor Interactions Derived from Target-Mediated Drug Disposition.
Lambertus A Peletier, Johan Gabrielsson

AAPS J· May 2018

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In vivo potency revisited - Keep the target in sight.
Johan Gabrielsson, Lambertus A Peletier, Stephan Hjorth

Pharmacol Ther· April 2018

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Impact of mathematical pharmacology on practice and theory: four case studies.
Lambertus A Peletier, Johan Gabrielsson

J Pharmacokinet Pharmacodyn· February 2018

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Model-Based Evaluation of Radiation and Radiosensitizing Agents in Oncology.
Tim Cardilin, Joachim Almquist, Mats Jirstrand, Astrid Zimmermann, Samer El Bawab, Johan Gabrielsson

CPT Pharmacometrics Syst Pharmacol· January 2018

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Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments.
Robert Andersson, Tobias Kroon, Joachim Almquist, Mats Jirstrand, Nicholas D Oakes, Johan Gabrielsson

J Pharmacokinet Pharmacodyn· June 2017

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Pharmacokinetic Steady-States Highlight Interesting Target-Mediated Disposition Properties.
Johan Gabrielsson, Lambertus A Peletier

AAPS J· May 2017

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Tumor Static Concentration Curves in Combination Therapy.
Tim Cardilin, Joachim Almquist, Mats Jirstrand, Alexandre Sostelly, Christiane Amendt, Johan Gabrielsson

AAPS J· March 2017

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Erratum to: Tumor Static Concentration Curves in Combination Therapy.
Tim Cardilin, Joachim Almquist, Mats Jirstand, Alexandre Soselly, Christiane Amendt, Johan Gabrielsson

AAPS J· March 2017

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Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats[S].
Tobias Kroon, Tania Baccega, Arne Olsén, Johan Gabrielsson, Nicholas D Oakes

J Lipid Res· January 2017

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Mixture dynamics: Combination therapy in oncology.
Johan Gabrielsson, Francis D Gibbons, Lambertus A Peletier

Eur J Pharm Sci· June 2016

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