Publications by authors named "Nicholas Doerr"

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Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction.
Hannah Pellegrini, Elizabeth H Sharpe, Guangyi Liu, Eiko Nishiuchi, Nicholas Doerr

J Biol Chem· September 2023

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Restoration of atypical protein kinase C ζ function in autosomal dominant polycystic kidney disease ameliorates disease progression.
Masaw Akbari, Jonathan D West, Nicholas Doerr, Kevin R Kipp, Neda Marhamati

Proc Natl Acad Sci U S A· July 2022

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Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease.
Erin E Olsan, Jonathan D West, Jacob A Torres, Nicholas Doerr, Thomas Weimbs

Am J Physiol Renal Physiol· July 2018

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Regulation of Polycystin-1 Function by Calmodulin Binding.
Nicholas Doerr, Yidi Wang, Kevin R Kipp, Guangyi Liu, Jesse J Benza

PLoS One· August 2017

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Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA.
Benjamin Rothé, Lucia Leal-Esteban, Florian Bernet, Séverine Urfer, Nicholas Doerr

Mol Cell Biol· October 2015

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The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.
Jeffrey J Talbot, Xuewen Song, Xiaofang Wang, Markus M Rinschen, Nicholas Doerr

J Am Soc Nephrol· August 2014

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Polycystin-1 regulates STAT activity by a dual mechanism.
Jeffrey J Talbot, Jonathan M Shillingford, Shivakumar Vasanth, Nicholas Doerr, Sambuddho Mukherjee

Proc Natl Acad Sci U S A· May 2011

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Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.
Daniel S La, Julie Belzile, James V Bready, Angela Coxon, Thomas DeMelfi, Nicholas Doerr

J Med Chem· March 2008

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Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors.
Matthew M Weiss, Jean-Christophe Harmange, Anthony J Polverino, David Bauer, Loren Berry, Nicholas Doerr

J Med Chem· March 2008

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Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.
Jean-Christophe Harmange, Matthew M Weiss, Julie Germain, Anthony J Polverino, George Borg, Nicholas Doerr

J Med Chem· March 2008

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Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors.
Michele H Potashman, James Bready, Angela Coxon, Thomas M DeMelfi, Lucian DiPietro, Nicholas Doerr

J Med Chem· September 2007

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Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.
Kurt Redlich, Birgit Görtz, Silvia Hayer, Jochen Zwerina, Nicholas Doerr

Am J Pathol· February 2004

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