Publications by authors named "Shivakumar Vasanth"

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Dysregulation of DNA repair genes in Fuchs endothelial corneal dystrophy.
Shazia Ashraf, Neha Deshpande, Shivakumar Vasanth, Geetha Melangath, Raymond J Wong

Exp Eye Res· June 2023

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Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy.
Taiga Miyajima, Geetha Melangath, Shan Zhu, Neha Deshpande, Shivakumar Vasanth

Free Radic Biol Med· February 2020

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Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected.
Cailing Liu, Taiga Miyajima, Geetha Melangath, Takashi Miyai, Shivakumar Vasanth

Proc Natl Acad Sci U S A· January 2020

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Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy.
Takashi Miyai, Shivakumar Vasanth, Geetha Melangath, Neha Deshpande, Varun Kumar

Am J Pathol· October 2019

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Identification of a Novel TCF4 Isoform in the Human Corneal Endothelium.
Allen O Eghrari, Shivakumar Vasanth, Briana C Gapsis, Henry Bison, Ula Jurkunas

Cornea· July 2018

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Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells.
Muhammad Ali, Shahid Y Khan, Shivakumar Vasanth, Mariya R Ahmed, Ruiqiang Chen

Invest Ophthalmol Vis Sci· May 2018

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NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy.
Kishore Reddy Katikireddy, Tomas L White, Taiga Miyajima, Shivakumar Vasanth, Duna Raoof

Free Radic Biol Med· February 2018

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Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy.
Anne-Sophie Benischke, Shivakumar Vasanth, Takashi Miyai, Kishore Reddy Katikireddy, Tomas White

Sci Rep· July 2017

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CTG18.1 Expansion in TCF4 Increases Likelihood of Transplantation in Fuchs Corneal Dystrophy.
Allen O Eghrari, Shivakumar Vasanth, Jiangxia Wang, Farnoosh Vahedi, S Amer Riazuddin

Cornea· January 2017

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FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1.
Shahid Y Khan, Shivakumar Vasanth, Firoz Kabir, John D Gottsch, Arif O Khan

Nat Commun· April 2016

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Expansion of CTG18.1 Trinucleotide Repeat in TCF4 Is a Potent Driver of Fuchs' Corneal Dystrophy.
Shivakumar Vasanth, Allen O Eghrari, Briana C Gapsis, Jiangxia Wang, Nicolas F Haller

Invest Ophthalmol Vis Sci· July 2015

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Metabolic regulation and energy homeostasis through the primary Cilium.
Edwin C Oh, Shivakumar Vasanth, Nicholas Katsanis

Cell Metab· January 2015

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Dosage changes of a segment at 17p13.1 lead to intellectual disability and microcephaly as a result of complex genetic interaction of multiple genes.
Claudia M B Carvalho, Shivakumar Vasanth, Marwan Shinawi, Chad Russell, Melissa B Ramocki

Am J Hum Genet· November 2014

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Mutations in AGBL1 cause dominant late-onset Fuchs corneal dystrophy and alter protein-protein interaction with TCF4.
S Amer Riazuddin, Shivakumar Vasanth, Nicholas Katsanis, John D Gottsch

Am J Hum Genet· October 2013

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Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease.
Kristin Lichti-Kaiser, Gary ZeRuth, Hong Soon Kang, Shivakumar Vasanth, Anton M Jetten

Vitam Horm· August 2012

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Polycystin-1 regulates STAT activity by a dual mechanism.
Jeffrey J Talbot, Jonathan M Shillingford, Shivakumar Vasanth, Nicholas Doerr, Sambuddho Mukherjee

Proc Natl Acad Sci U S A· May 2011

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Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2).
Shivakumar Vasanth, Gary ZeRuth, Hong Soon Kang, Anton M Jetten

J Biol Chem· February 2011

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Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.
Hong Soon Kang, Gary ZeRuth, Kristin Lichti-Kaiser, Shivakumar Vasanth, Zhengyu Yin

Histol Histopathol· November 2010

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Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease.
Seng Hui Low, Shivakumar Vasanth, Claire H Larson, Sambuddho Mukherjee, Nikunj Sharma

Dev Cell· January 2006

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