Publications by authors named "Nicholas Ho"

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Heimdall: A Modular Framework for Tokenization in Single-Cell Foundation Models.
Ellie Haber, Shahul Alam, Nicholas Ho, Renming Liu, Evan Trop

bioRxiv· November 2025

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Participatory systems modelling for youth mental health: agility and adaptiveness to enhance stakeholder engagement and knowledge sharing.
Sarah Piper, Victoria Loblay, Yun Ju Christine Song, Grace Yeeun Lee, Samantha Huntley, Nicholas Ho, Seyed Hossein Hosseini

Int J Ment Health Syst· October 2025

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Multimodal AI predicts clinical outcomes of drug combinations from preclinical data.
Yepeng Huang, Xiaorui Su, Varun Ullanat, Intae Moon, Ivy Liang, Nicholas Ho

ArXiv· September 2025

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Examining the Impact of Youth Mental Health Services Capacity Growth Trajectories and Digital Interventions on Youth Mental Health Outcomes: System Dynamics Modeling Analysis.
Seyed Hossein Hosseini, Nicholas Ho, Samantha Huntley, Sarah Piper, Paul Crosland, Zoe Waterhouse-Bushnell

J Med Internet Res· August 2025

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Interplay between Matrix Viscoelasticity and Integrin Engagement Modulates Cancer-Associated Fibroblast States.
Yunyun Wang, Zixuan Zhao, Nicholas Ching Wei Ho, Narayanan Gopalakrishna Iyer, Eliza Li Shan Fong

Adv Healthc Mater· July 2025

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Beyond capacity limits: can social cohesion offset the impact of service constraints on youth mental health?
Jo-An Occhipinti, Nicholas Ho, Paul Crosland, Sam Huntley, Wendy Hawkins, Seyed Hossein Hosseini

Eur Psychiatry· June 2025

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The calcium channel agonist (±)-BAY-K-8644 attenuates the ability of gabapentinoids to increase the potency of fentanyl and heroin and decrease the potency of cocaine and d-methamphetamine to elicit discriminative stimulus effects in rats.
Takato Hiranita, Amanda K Grisham, Abram E Mijares, Nicholas P Ho, Charles P France

J Pharmacol Exp Ther· May 2025

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Diving Deep: Profiling Exhausted T Cells in the Tumor Microenvironment Using Spectral Flow Cytometry.
Karen Wei Weng Teng, Weng Hua Khoo, Nicholas Ching Wei Ho, S Jasemine Yang, Douglas C Wilson, Shu Wen Samantha Ho

Cytometry A· April 2025

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Incorporating Complexity and System Dynamics into Economic Modelling for Mental Health Policy and Planning.
Paul Crosland, Deborah A Marshall, Seyed Hossein Hosseini, Nicholas Ho, Catherine Vacher

Pharmacoeconomics· December 2024

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The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic α receptor activity in vitro and in vivo.
Samuel Obeng, Morgan L Crowley, Marco Mottinelli, Francisco León, Julio D Zuarth Gonzalez, Nicholas P Ho, Lance R McMahon

Eur J Pharmacol· October 2024

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Comparison of the -Opioid Receptor Antagonists Methocinnamox and Naloxone to Reverse and Prevent the Ventilatory Depressant Effects of Fentanyl, Carfentanil, 3-Methylfentanyl, and Heroin in Male Rats.
Takato Hiranita, Nicholas P Ho, Charles P France

J Pharmacol Exp Ther· September 2024

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Reducing mental health emergency visits: population-level strategies from participatory modelling.
Catherine Vacher, Nicholas Ho, Adam Skinner, Paul Crosland, Seyed Hossein Hosseini

BMC Psychiatry· September 2024

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Bidirectional linkage of DNA barcodes for the multiplexed mapping of higher-order protein interactions in cells.
Yu Liu, Noah R Sundah, Nicholas R Y Ho, Wan Xiang Shen, Yun Xu, Zhonglang Yu

Nat Biomed Eng· July 2024

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Bioengineered Hydrogels Recapitulate Fibroblast Heterogeneity in Cancer.
Nicholas Ching Wei Ho, Josephine Yu Yan Yap, Zixuan Zhao, Yunyun Wang, Kanishka Fernando, Hong Sheng Quah

Adv Sci (Weinh)· May 2024

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Bioengineered hydrogels enhance ex vivo preservation of patient-derived tumor explants for drug evaluation.
Christabella Adine, Kanishka Fernando, Nicholas Ching Wei Ho, Hong Sheng Quah, Samantha Shu Wen Ho

Biomaterials· March 2024

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Cost-effectiveness of system-level mental health strategies for young people in the Australian Capital Territory: a dynamic simulation modelling study.
Paul Crosland, Nicholas Ho, Seyed Hossein Hosseini, Catherine Vacher, Adam Skinner

Lancet Psychiatry· February 2024

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Ventilatory Effects of Fentanyl, Heroin, and -Methamphetamine, Alone and in Mixtures in Male Rats Breathing Normal Air .
Takato Hiranita, Nicholas P Ho, Charles P France

J Pharmacol Exp Ther· January 2024

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Pharmacokinetic and Pharmacodynamic Consequences of Cytochrome P450 3A Inhibition on Mitragynine Metabolism in Rats.
Shyam H Kamble, Samuel Obeng, Francisco León, Luis F Restrepo, Tamara I King, Erin C Berthold, Nicholas P Ho, Lance R McMahon

J Pharmacol Exp Ther· June 2023

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Improving access to mental health care: a system dynamics model of direct access to specialist care and accelerated specialist service capacity growth.
Catherine Vacher, Adam Skinner, Jo-An Occhipinti, Sebastian Rosenberg, Nicholas Ho

Med J Aust· April 2023

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Interactive Effects of -Opioid and Adrenergic- Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine.
Samuel Obeng, Francisco Leon, Avi Patel, Julio D Zuarth Gonzalez, Lucas Chaves Da Silva, Nicholas P Ho, Lance R McMahon

J Pharmacol Exp Ther· December 2022

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Dynamic networks of psychological symptoms, impairment, substance use, and social support: The evolution of psychopathology among emerging adults.
Jacob J Crouse, Nicholas Ho, Jan Scott, Richard Parker, Shin Ho Park, Nicholas G Martin

Eur Psychiatry· June 2022

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Hepatocellular carcinoma organoid co-cultures mimic angiocrine crosstalk to generate inflammatory tumor microenvironment.
Joanne Tze Chin Lim, Leng Gek Kwang, Nicholas Ching Wei Ho, Clarissa Chin Min Toh, Nathaniel Sheng Hua Too, Lissa Hooi, Pierce Kah-Hoe Chow, Edward Kai-Hua Chow

Biomaterials· May 2022

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Optimizing Strategies for Improving Mental Health in Victoria, Australia during the COVID-19 Era: A System Dynamics Modelling Study.
Catherine Vacher, Nicholas Ho, Adam Skinner, Jo Robinson, Louise Freebairn

Int J Environ Res Public Health· May 2022

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